New antithrombotic RGD-mimetics with high bioavailability

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 20, 1996, Pages 2425-2430

  Gante, Joachim ^a   Juraszyk, Horst ^a   Raddatz, Peter ^a   Wurziger, Hanns ^a   Bernotat Danielowski, Sabine ^a   Melzer, Guido ^a   Rippmann, Friedrich ^a  

^a MERCK KGAA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; OXAZOLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG SYNTHESIS; GUINEA PIG; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0030598191     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00445-3     Document Type: Article

References (12)

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2. 2. a) Ojima, J.; Chakravarty, S.; Dong, Q. Bioorg. Med Chem. 1995, 3, 337.
3. b) Zablocky, J. A.; Nicholson, N. S.; Feigen, L. P. Exp. Opin. Invest. Drugs 1994, 3, 437.
4. 3. Gante, J. Angew. Chem., Int. Ed. Engl. 1994, 33, 1699.
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6. b) Müller, T. H.; Schurer, H.; Waldmann, L.; Bauer, E.; Himmelsbach, E.; Binder, K. Thromb. Haemostas. 1993, 69, 975.
7. 5. Zablocky, J. A. J. Med. Chem. 1995, 38, 2378.
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9. b) Hayashi, S.; Furukawa, M.; Fujino, Y.; Matsuishi, N.; Ohkawara, T. Chem. Pharm. Bull. 1969, 17, 145.
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12. 8. Falchi, M.; Biella, G.; Mazza, D. Drugs Exptl. Clin. Res. 1983, IX(6), 419-922.