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Volumn 107, Issue 2, 1996, Pages 285-291

Phytohemagglutinin-L (PHA-L) lectin surface binding of N-linked β1-6 carbohydrate and its relationship to activated mutant ras in human pancreatic cancer cell-lines

Author keywords

K ras oncogen; Lectin; Pancreatic cancer; Phytohemagglutinin; 1 6 N linked carbohydrate

Indexed keywords

CARBOHYDRATE; CELL SURFACE PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; LECTIN; PHOSPHORUS 32; PHYTOHEMAGGLUTININ; RAS PROTEIN;

EID: 0030598158     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04386-8     Document Type: Article
Times cited : (17)

References (18)
  • 1
    • 0027955218 scopus 로고
    • The ras signal transduction pathway
    • [1] Khosravi-Far, R. and Der, C.J. (1994) The ras signal transduction pathway, Cancer Metast. Rev., 13, 67-89.
    • (1994) Cancer Metast. Rev. , vol.13 , pp. 67-89
    • Khosravi-Far, R.1    Der, C.J.2
  • 2
    • 0025195107 scopus 로고
    • Accumulation of p21ras-GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity
    • [2] Satoh, T., Endo, M., Nakafuku, M., Akiyama, T., Yamamoto, T. and Kaziro, Y. (1990) Accumulation of p21ras-GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity, Proc. Natl. Acad. Sci. USA, 87, 7926-7929.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7926-7929
    • Satoh, T.1    Endo, M.2    Nakafuku, M.3    Akiyama, T.4    Yamamoto, T.5    Kaziro, Y.6
  • 4
    • 0027254425 scopus 로고
    • Genotypic classification of colonic adenocarcinoma
    • [4] Finkelstein, S.D., Sayegh, R., Christensen, S. and Swalsky, P.A. (1993) Genotypic classification of colonic adenocarcinoma, Cancer, 71, 3828-3838.
    • (1993) Cancer , vol.71 , pp. 3828-3838
    • Finkelstein, S.D.1    Sayegh, R.2    Christensen, S.3    Swalsky, P.A.4
  • 5
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • [5] Bos, J.L. (1989) Ras oncogenes in human cancer: a review, Cancer Res., 49, 4682-4689.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 6
    • 0025196234 scopus 로고
    • Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing
    • [6] Tada, M., Yokosuka, O., Omata, M., Ohto, M. and Isono, K. (1990) Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing, Cancer, 66, 930-935.
    • (1990) Cancer , vol.66 , pp. 930-935
    • Tada, M.1    Yokosuka, O.2    Omata, M.3    Ohto, M.4    Isono, K.5
  • 7
    • 0028958222 scopus 로고
    • Increased prevalence of K-ras oncogene mutations in lung adenocarcinoma
    • [7] Mills, N.E., Fishman, C.L., Rom, W.N., Dubin, N. and Jacobson, D.R. (1995) Increased prevalence of K-ras oncogene mutations in lung adenocarcinoma, Cancer Res., 55, 1444-1447.
    • (1995) Cancer Res. , vol.55 , pp. 1444-1447
    • Mills, N.E.1    Fishman, C.L.2    Rom, W.N.3    Dubin, N.4    Jacobson, D.R.5
  • 8
    • 0023255440 scopus 로고
    • β1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis
    • [8] Dennis, J.W., Laferte, S., Waghorne, C., Breitman, M.L. and Kerbel, R.S. (1987) β1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis, Science, 236, 582-585.
    • (1987) Science , vol.236 , pp. 582-585
    • Dennis, J.W.1    Laferte, S.2    Waghorne, C.3    Breitman, M.L.4    Kerbel, R.S.5
  • 9
    • 0024321039 scopus 로고
    • Oncogenes conferring metastatic potential induce increased branching of Asn-linked oligosaccharides in rat2 fibroblasts
    • [9] Dennis, J.W., Kosh, K., Bryce, D.M. and Breitman, M.L. (1989) Oncogenes conferring metastatic potential induce increased branching of Asn-linked oligosaccharides in rat2 fibroblasts, Oncogene, 4, 853-860.
    • (1989) Oncogene , vol.4 , pp. 853-860
    • Dennis, J.W.1    Kosh, K.2    Bryce, D.M.3    Breitman, M.L.4
  • 10
    • 0024116793 scopus 로고
    • Ras (proto)oncogene induces N-linked carbohydrate modification: Temporal relationship with induction of invasive potential
    • [10] Bolscher, J.G.M., van der Bijl, M.M.W., Neefjes, J.J., Hall, A., Smets, L.A. and Ploegh, H.L. (1988) Ras (proto)oncogene induces N-linked carbohydrate modification: temporal relationship with induction of invasive potential, EMBO J., 7, 3361-3368.
    • (1988) EMBO J. , vol.7 , pp. 3361-3368
    • Bolscher, J.G.M.1    Van Der Bijl, M.M.W.2    Neefjes, J.J.3    Hall, A.4    Smets, L.A.5    Ploegh, H.L.6
  • 11
    • 0020479688 scopus 로고
    • Characterization of the structural determinants required for the high affinity interaction of asparagine-linked oligosaccharides with immobilized Phaseolus vulgaris leukoagglutinating and erythroagglutinating lectins
    • [11] Cummings, R.D. and Kornfeld, S. (1982) Characterization of the structural determinants required for the high affinity interaction of asparagine-linked oligosaccharides with immobilized Phaseolus vulgaris leukoagglutinating and erythroagglutinating lectins, J. Biol. Chem., 257, 11230-11234.
    • (1982) J. Biol. Chem. , vol.257 , pp. 11230-11234
    • Cummings, R.D.1    Kornfeld, S.2
  • 12
    • 0026014062 scopus 로고
    • β1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia
    • [12] Fernandez, B., Sagman, U., Auger, M., Demetrio, M. and Dennis, J.W. (1991) β1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia, Cancer Res., 51, 718-723.
    • (1991) Cancer Res. , vol.51 , pp. 718-723
    • Fernandez, B.1    Sagman, U.2    Auger, M.3    Demetrio, M.4    Dennis, J.W.5
  • 13
    • 0028982795 scopus 로고
    • B1-6 branching of N-linked carbohydrate is associated with K-ras mutation in human colon carcinoma cell lines
    • [13] Wojciechowicz, D.C., Park, P.Y. and Paty, P.B. (1995) B1-6 branching of N-linked carbohydrate is associated with K-ras mutation in human colon carcinoma cell lines, Biochem. Biophys. Res. Commun., 212, 758-766.
    • (1995) Biochem. Biophys. Res. Commun. , vol.212 , pp. 758-766
    • Wojciechowicz, D.C.1    Park, P.Y.2    Paty, P.B.3
  • 14
    • 0025337018 scopus 로고
    • Platelet-derived growth factor stimulates formation of active p21ras-GTP complex in Swiss mouse 3T3 cells
    • [14] Satoh, T., Endo, M., Nakafuku, M., Nakamura, S. and Kaziro, Y. (1990) Platelet-derived growth factor stimulates formation of active p21ras-GTP complex in Swiss mouse 3T3 cells, Proc. Natl. Acad. Sci. USA, 87, 5993-5997.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5993-5997
    • Satoh, T.1    Endo, M.2    Nakafuku, M.3    Nakamura, S.4    Kaziro, Y.5
  • 15
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage 4
    • [15] Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage 4, Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 16
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • [16] Towbin, H., Stachelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications, Proc. Natl. Acad. Sci. USA, 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Stachelin, T.2    Gordon, J.3
  • 17
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • [17] Fearon, E.R. and Vogelstein, B.A. (1990) A genetic model for colorectal tumorigenesis, Cell, 61, 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.A.2
  • 18
    • 0011907914 scopus 로고    scopus 로고
    • CEA is the major PHA-L reactive glycoprotein in colon carcinoma cell lines and tumors: Relationship to K-ras activation
    • [18] Wojciechowicz, D.C., Park, P.Y., Cohen, A. and Paty, P.B. (1996) CEA is the major PHA-L reactive glycoprotein in colon carcinoma cell lines and tumors: relationship to K-ras activation, Proc. Am. Assoc, Cancer Res., 37, 573.
    • (1996) Proc. Am. Assoc, Cancer Res. , vol.37 , pp. 573
    • Wojciechowicz, D.C.1    Park, P.Y.2    Cohen, A.3    Paty, P.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.