메뉴 건너뛰기




Volumn 728, Issue 1, 1996, Pages 47-56

Nerve growth factor (NGF) content in adult rat brain tissues is several-fold higher than generally reported and is largely associated with sedimentable fractions

Author keywords

Association; Enzyme linked immunosorbent assay; Nerve growth factor; Nippocampus; Pellet; Rat brain

Indexed keywords

NERVE GROWTH FACTOR;

EID: 0030597991     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00386-1     Document Type: Article
Times cited : (32)

References (40)
  • 2
    • 0024382362 scopus 로고
    • Sustained elevation in hippocampal NGF-like biological activity following medial septal lesions in the rat
    • [2] Collins, F. and Crutcher, K.A., Sustained elevation in hippocampal NGF-like biological activity following medial septal lesions in the rat, Brain Res., 490 (1989) 355-360.
    • (1989) Brain Res. , vol.490 , pp. 355-360
    • Collins, F.1    Crutcher, K.A.2
  • 3
    • 0022406874 scopus 로고
    • Neurotrophic activity in the adult rat hippocampal formation: Regional distribution and increase after septal lesion
    • [3] Collins, F. and Crutcher, K.A., Neurotrophic activity in the adult rat hippocampal formation: regional distribution and increase after septal lesion, J. Neurosci., 5 (1985) 2809-2814.
    • (1985) J. Neurosci. , vol.5 , pp. 2809-2814
    • Collins, F.1    Crutcher, K.A.2
  • 4
    • 0028860452 scopus 로고
    • Effects of exogenous nerve growth factor upon sympathetic sprouting in the hippocampal formation
    • [4] Conner, J.M. and Varon, S., Effects of exogenous nerve growth factor upon sympathetic sprouting in the hippocampal formation, Exp. Neurol., 136 (1995) 123-135.
    • (1995) Exp. Neurol. , vol.136 , pp. 123-135
    • Conner, J.M.1    Varon, S.2
  • 5
    • 0026459967 scopus 로고
    • Distribution of nerve growth factor-like immunoreactive neurons in the adult rat brain following colchicine treatment
    • [5] Conner, J.M. and Varon, S., Distribution of nerve growth factor-like immunoreactive neurons in the adult rat brain following colchicine treatment, J. Comp. Neurol., 326 (1992) 347-362.
    • (1992) J. Comp. Neurol. , vol.326 , pp. 347-362
    • Conner, J.M.1    Varon, S.2
  • 6
    • 0026708320 scopus 로고
    • The localization of nerve growth factor-like immunoreactivity in the adult rat basal forebrain and hippocampal formation
    • [6] Conner, J.M., Muir, D., Varon, S., Hagg, T. and Manthorpe, M., The localization of nerve growth factor-like immunoreactivity in the adult rat basal forebrain and hippocampal formation, J. Comp. Neurol., 319 (1992) 454-462.
    • (1992) J. Comp. Neurol. , vol.319 , pp. 454-462
    • Conner, J.M.1    Muir, D.2    Varon, S.3    Hagg, T.4    Manthorpe, M.5
  • 7
    • 0012078217 scopus 로고
    • The adult rat hippocampus contains NGF in soluble and bound forms
    • [7] Costello, J.W., Conner, J.M., Burnham, P. and Varon, S., The adult rat hippocampus contains NGF in soluble and bound forms, Soc. Neurosci. Abstr., 20 (1994) 1093.
    • (1994) Soc. Neurosci. Abstr. , vol.20 , pp. 1093
    • Costello, J.W.1    Conner, J.M.2    Burnham, P.3    Varon, S.4
  • 8
    • 0025950097 scopus 로고
    • Hippocampal NGF levels are not reduced in the aged Fischer 344 rat
    • [8] Crutcher, K.A. and Weingartner, J., Hippocampal NGF levels are not reduced in the aged Fischer 344 rat, Neurobiol. Aging, 12 (1991) 449-454.
    • (1991) Neurobiol. Aging , vol.12 , pp. 449-454
    • Crutcher, K.A.1    Weingartner, J.2
  • 9
    • 0027197191 scopus 로고
    • Detection of NGF-like activity in human brain tissue: Increased levels in Alzheimer's disease
    • [9] Crutcher, K.A., Scott, S.A., Liang, S., Everson, W.V. and Weingartner, J., Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease, J. Neurosci., 13 (1993) 2540-2550.
    • (1993) J. Neurosci. , vol.13 , pp. 2540-2550
    • Crutcher, K.A.1    Scott, S.A.2    Liang, S.3    Everson, W.V.4    Weingartner, J.5
  • 10
    • 0025766899 scopus 로고
    • Increased level of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis
    • [10] Ernfors, P., Bengzon, J., Kokaia, Z., Persson, H. and Lindvall, O., Increased level of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis, Neuron, 7 (1991) 165-176.
    • (1991) Neuron , vol.7 , pp. 165-176
    • Ernfors, P.1    Bengzon, J.2    Kokaia, Z.3    Persson, H.4    Lindvall, O.5
  • 11
    • 0022480016 scopus 로고
    • Time course of the elevation of nerve growth factor (NGF) content in the hippocampus and septum following lesions of the septohippocampal pathway in rats
    • [11] Gasser, U.E., Weskamp, G., Otten, U. and Dravid, A.R., Time course of the elevation of nerve growth factor (NGF) content in the hippocampus and septum following lesions of the septohippocampal pathway in rats, Brain. Res., 376 (1986) 351-356.
    • (1986) Brain. Res. , vol.376 , pp. 351-356
    • Gasser, U.E.1    Weskamp, G.2    Otten, U.3    Dravid, A.R.4
  • 12
    • 0025486143 scopus 로고
    • Nerve growth factor infusion into the denervated adult rat hippocampal formation promotes its cholinergic reinnervation
    • [12] Hagg, T., Vahlsing, H.L., Manthorpe, M. and Varon, S., Nerve growth factor infusion into the denervated adult rat hippocampal formation promotes its cholinergic reinnervation, Neuroscience, 10 (1990) 3087-3092.
    • (1990) Neuroscience , vol.10 , pp. 3087-3092
    • Hagg, T.1    Vahlsing, H.L.2    Manthorpe, M.3    Varon, S.4
  • 13
    • 0025025869 scopus 로고
    • Nerve growth factor in the primate central nervous system: Regional distribution and ontogeny
    • [13] Hayashi, M., Yamashita, A. and Shimizu, K., Nerve growth factor in the primate central nervous system: regional distribution and ontogeny, Neuroscience, 36 (1990) 683-689.
    • (1990) Neuroscience , vol.36 , pp. 683-689
    • Hayashi, M.1    Yamashita, A.2    Shimizu, K.3
  • 14
    • 0002517542 scopus 로고
    • An improved rapid and highly sensitive enzyme immunoassay for nerve growth factor
    • [14] Hellweg, R., Hock, C. and Hartung, H.-D., An improved rapid and highly sensitive enzyme immunoassay for nerve growth factor, Technique, 1 (1989) 43-48.
    • (1989) Technique , vol.1 , pp. 43-48
    • Hellweg, R.1    Hock, C.2    Hartung, H.-D.3
  • 16
    • 0026725018 scopus 로고
    • Phosphatidylinositol-glycan-specific phospholipase D is an amphiphilic glycoprotein that in serum is associated with high density lipoproteins
    • [16] Hoener, M.C. and Brodbeck, U., Phosphatidylinositol-glycan-specific phospholipase D is an amphiphilic glycoprotein that in serum is associated with high density lipoproteins, Eur. J. Biochem., 206 (1992) 747-757.
    • (1992) Eur. J. Biochem. , vol.206 , pp. 747-757
    • Hoener, M.C.1    Brodbeck, U.2
  • 17
    • 0023846412 scopus 로고
    • Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs
    • [17] Korsching, S. and Thoenen, H., Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs, Dev. Biol., 126 (1988) 40-46.
    • (1988) Dev. Biol. , vol.126 , pp. 40-46
    • Korsching, S.1    Thoenen, H.2
  • 18
    • 0344106663 scopus 로고
    • Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation
    • [18] Korsching, S., Auburger, G., Heumann, R., Scott, J. and Thoenen, H., Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation, EMBO J., 4 (1985) 1389-1393.
    • (1985) EMBO J. , vol.4 , pp. 1389-1393
    • Korsching, S.1    Auburger, G.2    Heumann, R.3    Scott, J.4    Thoenen, H.5
  • 19
    • 0022526809 scopus 로고
    • Cholinergic denervation of the rat hippocampus by fimbrial transection leads to transient accumulation of nerve growth factor (NGF) without a change in mRNA NGF content
    • [19] Korsching, S., Heumann, R., Thoenen, H. and Hefti, F., Cholinergic denervation of the rat hippocampus by fimbrial transection leads to transient accumulation of nerve growth factor (NGF) without a change in mRNA NGF content, Neurosci. Lett., 66 (1986) 175-180.
    • (1986) Neurosci. Lett. , vol.66 , pp. 175-180
    • Korsching, S.1    Heumann, R.2    Thoenen, H.3    Hefti, F.4
  • 21
    • 0023131144 scopus 로고
    • Highly sensitive enzyme immunoassays for β-nerve growth factor
    • [21] Larkfors, L. and Ebendal, T., Highly sensitive enzyme immunoassays for β-nerve growth factor, J. Immunol. Meth., 97 (1987) 41-47.
    • (1987) J. Immunol. Meth. , vol.97 , pp. 41-47
    • Larkfors, L.1    Ebendal, T.2
  • 22
    • 0023574881 scopus 로고
    • Decreased levels of nerve growth factor (NGF) and its messenger RNA in the aged rat brain
    • [22] Larkfors, L., Ebendal, T., Whittemore, S.R., Persson, H., Hoffer, B. and Olson, L., Decreased levels of nerve growth factor (NGF) and its messenger RNA in the aged rat brain, Mol. Brain Res., 3 (1987) 55-60.
    • (1987) Mol. Brain Res. , vol.3 , pp. 55-60
    • Larkfors, L.1    Ebendal, T.2    Whittemore, S.R.3    Persson, H.4    Hoffer, B.5    Olson, L.6
  • 23
    • 0023514272 scopus 로고
    • Nerve growth factor protein level increases in the adult rat hippocampus after specific cholinergic lesion
    • [23] Larkfors, L., Stromberg, I., Ebendal, T. and Olson, L., Nerve growth factor protein level increases in the adult rat hippocampus after specific cholinergic lesion, J. Neurosci. Res., 18 (1987) 552-531.
    • (1987) J. Neurosci. Res. , vol.18 , pp. 552-1531
    • Larkfors, L.1    Stromberg, I.2    Ebendal, T.3    Olson, L.4
  • 24
    • 0028299995 scopus 로고
    • Relationship of APP mRNA transcripts and levels of NGF and low-affinity NGF receptors to behavioral measures of age-related cognitive dysfunction
    • [24] Lindner, M., Dworetzky, S.I., Sampson, C. and Loy, R., Relationship of APP mRNA transcripts and levels of NGF and low-affinity NGF receptors to behavioral measures of age-related cognitive dysfunction, J. Neurosci., 14 (1994) 2282-2289.
    • (1994) J. Neurosci. , vol.14 , pp. 2282-2289
    • Lindner, M.1    Dworetzky, S.I.2    Sampson, C.3    Loy, R.4
  • 25
    • 0022686460 scopus 로고
    • An automated colorimetric microassay for neuronotrophic factors
    • [25] Manthorpe, M., Fagnani, R., Skaper, S.D. and Varon, S., An automated colorimetric microassay for neuronotrophic factors, Dev. Brain Res., 25 (1986) 191-198.
    • (1986) Dev. Brain Res. , vol.25 , pp. 191-198
    • Manthorpe, M.1    Fagnani, R.2    Skaper, S.D.3    Varon, S.4
  • 26
    • 0029031207 scopus 로고
    • BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: Partial disagreement with mRNA levels
    • [26] Nawa, H., Carnahan, J. and Gall, C., BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels, Eur. J. Neurosci., 7 (1995) 1527-1535.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1527-1535
    • Nawa, H.1    Carnahan, J.2    Gall, C.3
  • 27
    • 0012017237 scopus 로고
    • Improved extraction allows detection of decreased NGF levels in peripheral tissues following denervation
    • [27] Rush, R.A., Bridges, D.C.McL., Liu, D.T., Reid, M.T. and Zettler, C., Improved extraction allows detection of decreased NGF levels in peripheral tissues following denervation, Soc. Neurosci. Abstr., 21 (1995) 37.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 37
    • Rush, R.A.1    Bridges, D.C.Mc.L.2    Liu, D.T.3    Reid, M.T.4    Zettler, C.5
  • 28
    • 0024380994 scopus 로고
    • Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth
    • [28] Saffran, B.N., Woo, J.E., Mobley, W.C. and Crutcher, K.A., Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth, Brain Res., 492 (1989) 245-254.
    • (1989) Brain Res. , vol.492 , pp. 245-254
    • Saffran, B.N.1    Woo, J.E.2    Mobley, W.C.3    Crutcher, K.A.4
  • 29
    • 0028284131 scopus 로고
    • Increased NGF-like activity in young but not aged rat hippocampus after septal lesions
    • [29] Scott, S.A., Liang, S., Weingartner, J.A. and Crutcher, K.A., Increased NGF-like activity in young but not aged rat hippocampus after septal lesions, Neurobiol. Aging, 15 (1994) 337-346.
    • (1994) Neurobiol. Aging , vol.15 , pp. 337-346
    • Scott, S.A.1    Liang, S.2    Weingartner, J.A.3    Crutcher, K.A.4
  • 30
    • 0029022112 scopus 로고
    • Nerve growth factor in Alzheimer's disease: Increased levels throughout the brain coupled with declines in nucleus basalis
    • [30] Scott, S.A., Mufson, E.J., Weingartner, J.A., Skau, K.A. and Crutcher, K.A., Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis, J. Neurosi., 15 (1995) 6213-6221.
    • (1995) J. Neurosi. , vol.15 , pp. 6213-6221
    • Scott, S.A.1    Mufson, E.J.2    Weingartner, J.A.3    Skau, K.A.4    Crutcher, K.A.5
  • 31
    • 0026703788 scopus 로고
    • Temporal profiles of nerve growth factor β-subunit level in rat brain regions after transient ischemia
    • [31] Shozuhara, H., Onodera, H., Katoh-Semba, R., Kato, K., Yamasaki, Y. and Kogure, K., Temporal profiles of nerve growth factor β-subunit level in rat brain regions after transient ischemia, J. Neurochem., 59 (1992) 175-180.
    • (1992) J. Neurochem. , vol.59 , pp. 175-180
    • Shozuhara, H.1    Onodera, H.2    Katoh-Semba, R.3    Kato, K.4    Yamasaki, Y.5    Kogure, K.6
  • 32
    • 0025614328 scopus 로고
    • Recombinant human β-nerve growth factor (NGF): Biological activity and properties in an enzyme immunoassay
    • [32] Soderstrom, S., Hallbook, F., Ibanez, C.F., Persson, H. and Ebendal, T., Recombinant human β-nerve growth factor (NGF): biological activity and properties in an enzyme immunoassay, J. Neurosci. Res., 27 (1990) 665-667.
    • (1990) J. Neurosci. Res. , vol.27 , pp. 665-667
    • Soderstrom, S.1    Hallbook, F.2    Ibanez, C.F.3    Persson, H.4    Ebendal, T.5
  • 33
    • 0029050698 scopus 로고
    • Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats
    • [33] Van der Zee, C.E.E.M., Rashid, K., Le, K., Moore, K.-A., Stanisz, J., Diamond, J., Racine, R.J. and Fahnestock, M., Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats, J. Neurosci., 15 (1995) 5316-5323.
    • (1995) J. Neurosci. , vol.15 , pp. 5316-5323
    • Van Der Zee, C.E.E.M.1    Rashid, K.2    Le, K.3    Moore, K.-A.4    Stanisz, J.5    Diamond, J.6    Racine, R.J.7    Fahnestock, M.8
  • 34
    • 0002883735 scopus 로고
    • The isolation and assay of the nerve growth factor proteins
    • R. Fried (Ed.), M. Dekker, New York
    • [34] Varon, S., Nomura, J., Perez-Polo, J.R. and Shooter, E.M., The isolation and assay of the nerve growth factor proteins. In R. Fried (Ed.), Methods in Neurochemistry, M. Dekker, New York, 1992, pp. 203-229.
    • (1992) Methods in Neurochemistry , pp. 203-229
    • Varon, S.1    Nomura, J.2    Perez-Polo, J.R.3    Shooter, E.M.4
  • 35
    • 0019438912 scopus 로고
    • Trophic activities for dorsal root and sympathetic ganglionic neurons in medium conditioned by Schwann and other peripheral cells
    • [35] Varon, S., Skaper, S.D., Manthorpe, M., Trophic activities for dorsal root and sympathetic ganglionic neurons in medium conditioned by Schwann and other peripheral cells, Dev. Brain. Res., 1 (1981) 73-87.
    • (1981) Dev. Brain. Res. , vol.1 , pp. 73-87
    • Varon, S.1    Skaper, S.D.2    Manthorpe, M.3
  • 36
    • 0023219442 scopus 로고
    • An enzyme-linked immunoassay for nerve growth factor (NGF): A tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues
    • [36] Weskamp, G. and Otten, U., An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues, J. Neurochem., 48 (1987) 1779-1786.
    • (1987) J. Neurochem. , vol.48 , pp. 1779-1786
    • Weskamp, G.1    Otten, U.2
  • 37
    • 0022522962 scopus 로고
    • Fimbriafornix lesion increases nerve growth factor content in adult rat septum and hippocampus
    • [37] Weskamp, G., Gasser, U.E., Dravid, A.R. and Otten, U., Fimbriafornix lesion increases nerve growth factor content in adult rat septum and hippocampus, Neurosci. Lett., 70 (1986) 121-126.
    • (1986) Neurosci. Lett. , vol.70 , pp. 121-126
    • Weskamp, G.1    Gasser, U.E.2    Dravid, A.R.3    Otten, U.4
  • 38
    • 0023626621 scopus 로고
    • The expression, localization and functional significance of β-nerve growth factor in the central nervous system
    • [38] Whittemore, S.R. and Seiger, A., The expression, localization and functional significance of β-nerve growth factor in the central nervous system, Brain Res. Rev., 12 (1987) 439-464.
    • (1987) Brain Res. Rev. , vol.12 , pp. 439-464
    • Whittemore, S.R.1    Seiger, A.2
  • 39
    • 0022503734 scopus 로고
    • Developmental and regional expression of β nerve growth factor messenger RNA and protein in the rat central nervous system
    • [39] Whittemore, S.R., Ebendal, T., Larkfors, L., Olson, L., Seiger, A., Stromberg, I. and Persson, H., Developmental and regional expression of β nerve growth factor messenger RNA and protein in the rat central nervous system. Proc. Natl. Acad. Sci. USA, 83 (1986) 817-821.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 817-821
    • Whittemore, S.R.1    Ebendal, T.2    Larkfors, L.3    Olson, L.4    Seiger, A.5    Stromberg, I.6    Persson, H.7
  • 40
    • 0023121847 scopus 로고
    • Increased β-nerve growth factor messenger RNA and protein levels in neonatal rat hippocampus following specific cholinergic lesions
    • [40] Whittemore, S.R., Larkfors, L., Ebendal, T., Holets, V.R., Ericsson, A. and Persson, H., Increased β-nerve growth factor messenger RNA and protein levels in neonatal rat hippocampus following specific cholinergic lesions, J. Neurosci., 7 (1987) 244-251.
    • (1987) J. Neurosci. , vol.7 , pp. 244-251
    • Whittemore, S.R.1    Larkfors, L.2    Ebendal, T.3    Holets, V.R.4    Ericsson, A.5    Persson, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.