Genomic organization of mouse Dishevelled genes

Gene

Volumn 180, Issue 1-2, 1996, Pages 121-123

  Yang, Yasheng ^a   Lijam, Nardos ^b   Sussman, Daniel J ^a   Tsang, Michael ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Development; Exon intron comparison; Wnt signal transduction

Indexed keywords

ANIMAL CELL; ARTICLE; DNA LIBRARY; EXON; GENE ISOLATION; GENE LOCUS; GENE STRUCTURE; INTRON; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESTRICTION MAPPING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CLONING, MOLECULAR; EXONS; INTRONS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEINS; RESTRICTION MAPPING;

ANIMALIA;

EID: 0030597369     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00430-1     Document Type: Article

References (18)

1. Beier, D.R., Dushkin, H. and Sussman, D.J. (1992) Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses. Proc. Natl. Acad. Sci. USA 89, 9102-9106.
2. Kilingensmith, J., Nusse, R. and Perrimon N. (1994) Dishevelled encodes a novel protein required for response of target cells to the wingless signal in Drosophila embryos. Genes Dev. 8, 113-130.
3. Lijam, N. and Sussman, D.J. (1995) Organization and promoter analysis of the mouse Dishevelled-1 gene. Genome Res. 5, 116-124.
4. McMahon, A.P. (1992) The Wnt family of developmental regulators. Trends Genet. 8, 236-242.
5. McMahon, A.P. and Bradley, A. (1990) The Wnt-1 (Int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62, 1073-1085.
6. Mount, S.M. (1982) A catalogue of splice junction sequences. Nucleic Acids Res. 10, 459-472.
7. Noordermeer, J., Klingensmith, J., Perrimon, N. and Nusse, R. (1994) Dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature 367, 80-82.
8. Nusse, R. and Varmus, H.E. (1992) Wnt genes. Cell 69, 1073-1087.
9. Parr, B.A. and McMahon, A.P. (1995) Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limbs. Nature 374, 350-353.
10. Siegfried, E., Wilder, E.L. and Perrimon, N. (1994) Components of wingless signalling in Drosophila. Nature 367, 76-79.
11. Sokol, S.Y., Klingensmith, J., Perrimon, N., and Itoh, K. (1995) Dorsalizing and neuralizing properties of Xdsh, a maternally expressed homolog of dishevelled. Development 121, 1637-1647.
12. Stark, K., Vainio, S., Vassilvere, G. and McMahon, A.P. (1994) Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372, 679-683.
13. Steitz, S.A., Tsang, M. and Sussman, D.J. (1996) Wnt mediated relocalization of dishevelled proteins. In Vitro Cell. Dev. Biol., in press.
14. Sussman, D.J., Klingensmith, J., Salinas, P., Adams, P.S., Nusse, R. and Perrimon, N. (1994) Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev. Biol. 166, 73-86.
15. Takada, S., Stark, K.L., Shea, M.J., Vassileva, G., McMahon, J.A. and McMahon, A.P. (1994) Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev. 8, 174-189.
16. Theisen, H., Purcell, J., Bennett, M., Kansagara, D., Syed, A. and Marsh, L.J. (1994) Dishevelled is required during wingless signalling to establish both cell polarity and cell identity. Development 120, 347-360.
17. Thomas, K.R. and Capecchi, M.R. (1990) Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346, 847-850.
18. Yanagawa, S., van Leeuwen, F., Wodarz, A., Klingensmith, J. and Nusse, R. (1995) The dishevelled protein is modified by wingless signalling in Drosophila. Genes Dev. 9, 1087-1097.