Preparation and evaluation of pectin beads

International Journal of Pharmaceutics

Volumn 137, Issue 1, 1996, Pages 133-136

  Aydìn, Zuhal ^a   Akbuǧa, Julide ^a  

^a MARMARA UNIVERSITY   (Turkey)

Author keywords

Atenolol; Beads; Ionotropic gelation; Pectin; Piroxicam; Sustained release

Indexed keywords

ATENOLOL; CALCIUM CHLORIDE; PECTIN; PIROXICAM;

DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; PRIORITY JOURNAL; SHORT SURVEY; SUSTAINED RELEASE PREPARATION;

EID: 0030596511     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04458-2     Document Type: Article

References (11)

1. Ashford, M., Fell, J., Attwood, D., Sharma, H. and Woodhead, P., An evaluation of pectin as a carrier for drug targeting to the colon. J. Controlled Release, 26 (1993) 213-220.
2. Aydìn, Z., Preparation and Evaluation of Pectin and Chitosan Beads. Master Thesis, University of Marmara, Turkey, 1995.
3. Bechard, S. and McMullen, J.N., Pectin-gelatin microglobules: effect of a cross-linking agent (formaldehyde) on in vitro dissolution rate. J. Pharm. Sci., 31 (1986) 91-98.
4. Bodmeier, R., Oh, K.H. and Pramar, Y., Preparation and evaluation drug-containing chitosan beads. Drug Dev. Ind. Pharm., 15 (1989) 1475-1494.
5. Cummings, J.H., Southgate, D.A.T., Branch, W.J., Wiggins, H.S., Houston, H., Jenkins, D.J.A., Jirraj, T. and Hill, M.T., The digestion of pectin in the human gut and its effect on calcium absorption and large bowel function. Br. J. Nutr., 41 (1979) 477-485.
6. McMullen, J.N., Newton, D.W. and Becker, C.H., Pectingelatin complex coacervates. II. Effect of microcapsulated sulfamerazine on size, morphology, recovery and extraction of water-dispersible microglobules. J. Pharm. Sci., 73 (1984) 1799-1803.
7. Meshali, M.M., El-Dein, E.Z., Omar, S.A. and Luzzi, L.A., Effect of pectin and rutin on the physicochemical properties of certain nonsteroidal anti-inflammatory drugs. Acta Pharm. Fennica, 100 (1991) 219-228.
8. Naggar, V.F., El-Khawas, M., Ismail, F.A. and Boraie, N.A., Pectin, a possible matrix for oral sustained-release preparations of water soluble drugs. S.T.P. Pharma Sci., 3 (1992) 227-234.
9. Radai, R. and Rubinstein, A., In vitro and in vivo analysis of colon specificity of calcium pectinate formulations. Proc. Int. Symp. Control Release Bioact. Mater, 20 (1993) 330-331.
10. Ritger, P.L. and Peppas, N.A., A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J. Controlled Release, 5 (1987) 37-42.
11. Takahashi, Y., Nambu, N. and Nagai, T., Interaction of several nonsteroidal anti-inflammatory drugs with pectin in aqueous solution and in solid state. Chem. Pharm. Bull., 26 (1978) 3836-3842.