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Volumn 49, Issue 1-3, 1996, Pages 45-58

Formation of recombinant proteins in Escherichia coli under control of a nitrogen regulated promoter at low and high cell densities

Author keywords

Escherichia coli; High cell density cultivation; Inducible promoter; Nitrogen limitation; Recombinant protein production

Indexed keywords

ANTIBODIES; COLIFORM BACTERIA; GROWTH KINETICS; PH EFFECTS; PROTEINS;

EID: 0030595051     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-1656(96)01521-0     Document Type: Article
Times cited : (7)

References (38)
  • 1
    • 0027181944 scopus 로고
    • Regulation of kdp operon expression in Escherichia coli: Evidence against turgor as signal for transcriptional control
    • Asha, H. and Gowrishankar, J. (1993) Regulation of kdp operon expression in Escherichia coli: evidence against turgor as signal for transcriptional control. J. Bacteriol. 175, 4528-4537.
    • (1993) J. Bacteriol. , vol.175 , pp. 4528-4537
    • Asha, H.1    Gowrishankar, J.2
  • 2
    • 0021271212 scopus 로고
    • Plasmid vectors for the selection of promoters
    • Brosius, J. (1984) Plasmid vectors for the selection of promoters. Gene 27, 154-160.
    • (1984) Gene , vol.27 , pp. 154-160
    • Brosius, J.1
  • 3
    • 0026006846 scopus 로고
    • A new family of sugar-inducible expression vectors for Escherichia coli
    • Cagnon, C., Valverde, V. and Masson, J.-M. (1991) A new family of sugar-inducible expression vectors for Escherichia coli. Protein Eng. 4, 843-847.
    • (1991) Protein Eng. , vol.4 , pp. 843-847
    • Cagnon, C.1    Valverde, V.2    Masson, J.-M.3
  • 4
    • 0022432255 scopus 로고
    • Improved oligonucleotide site-directed mutagenesis using M13 vectors
    • Carter, P., Bedouelle, H. and Winter, G. (1985) Improved oligonucleotide site-directed mutagenesis using M13 vectors. Nucleic Acids Res. 13, 4431-4443.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 4431-4443
    • Carter, P.1    Bedouelle, H.2    Winter, G.3
  • 5
    • 0026006215 scopus 로고
    • Procaryotic osmoregulation: Genetics and physiology
    • Csonka, L.N. and Hanson, A.D. (1991) Procaryotic osmoregulation: genetics and physiology. Annu. Rev. Microbiol. 45, 569-606.
    • (1991) Annu. Rev. Microbiol. , vol.45 , pp. 569-606
    • Csonka, L.N.1    Hanson, A.D.2
  • 9
    • 0028608807 scopus 로고
    • pOSEX: Vectors for osmotically controlled and finely tuned gene expression in Escherichia coli
    • Herbst, B., Kneip, S. and Bremer, E. (1994) pOSEX: vectors for osmotically controlled and finely tuned gene expression in Escherichia coli. Gene 151, 137-142.
    • (1994) Gene , vol.151 , pp. 137-142
    • Herbst, B.1    Kneip, S.2    Bremer, E.3
  • 10
    • 0024470362 scopus 로고
    • A new oxygen-regulated promoter for the expression of proteins in Escherichia coli
    • Hughes, D.E., Curtis, J.E., Koshla, C. and Bailey, J.E. (1989) A new oxygen-regulated promoter for the expression of proteins in Escherichia coli. BioTechniques 7, 1026-1028.
    • (1989) BioTechniques , vol.7 , pp. 1026-1028
    • Hughes, D.E.1    Curtis, J.E.2    Koshla, C.3    Bailey, J.E.4
  • 11
    • 0027976409 scopus 로고
    • Intracellular expression of Vitreoscilla hemoglobin alters Escherichia coli energy metabolism under oxygen-limited conditions
    • Kallio, P.T., Kim, D.J., Tsai, P.S. and Bailey, J.E. (1994) Intracellular expression of Vitreoscilla hemoglobin alters Escherichia coli energy metabolism under oxygen-limited conditions. Eur. J. Biochem. 219, 201-208.
    • (1994) Eur. J. Biochem. , vol.219 , pp. 201-208
    • Kallio, P.T.1    Kim, D.J.2    Tsai, P.S.3    Bailey, J.E.4
  • 12
    • 0024565852 scopus 로고
    • A chromogenic assay for the detection of plasmin generated by plasminogen activator immobilized on nitrocellulose using a para-nitroanilide synthetic peptide substrate
    • Kulisek, E.S., Holm, S.T. and Johnston, K.H. (1989) A chromogenic assay for the detection of plasmin generated by plasminogen activator immobilized on nitrocellulose using a para-nitroanilide synthetic peptide substrate. Anal. Biochem. 177, 78-84.
    • (1989) Anal. Biochem. , vol.177 , pp. 78-84
    • Kulisek, E.S.1    Holm, S.T.2    Johnston, K.H.3
  • 13
    • 0025938894 scopus 로고
    • Prokaryotic transcriptional enhancers and enhancer-binding proteins
    • Kustu, S., North, A.K. and Weiss, D.S. (1991) Prokaryotic transcriptional enhancers and enhancer-binding proteins. Trends Biochem. Sci. 16, 397-402.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 397-402
    • Kustu, S.1    North, A.K.2    Weiss, D.S.3
  • 14
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 227, 680-685.
    • (1970) Nature (Lond.) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 15
    • 0028339430 scopus 로고
    • Family of the major cold-shock protein, CspA (CS7.4), of Escherichia coli, whose members show a high sequence similarity with the eukaryotic Y-box binding proteins
    • Lee, S.J., Xie, A., Jiang, W., Etchegaray, J.P., Jones, P.G. and Inouye, M. (1994) Family of the major cold-shock protein, CspA (CS7.4), of Escherichia coli, whose members show a high sequence similarity with the eukaryotic Y-box binding proteins. Mol. Microbiol. 11, 833-839.
    • (1994) Mol. Microbiol. , vol.11 , pp. 833-839
    • Lee, S.J.1    Xie, A.2    Jiang, W.3    Etchegaray, J.P.4    Jones, P.G.5    Inouye, M.6
  • 16
    • 0028289538 scopus 로고
    • Adaptation of Escherichia coli to high osmolarity environments: Osmoregulation of the high-affinity glycine betaine transport system ProU
    • Lucht, J.M. and Bremer, E. (1994) Adaptation of Escherichia coli to high osmolarity environments: Osmoregulation of the high-affinity glycine betaine transport system ProU. FEMS Microbiol. Rev. 14, 3-20.
    • (1994) FEMS Microbiol. Rev. , vol.14 , pp. 3-20
    • Lucht, J.M.1    Bremer, E.2
  • 17
    • 0011807231 scopus 로고
    • Expression and properties of hybrid streptokinases extended by N-terminal plasminogen kringle domains
    • Dunny, G.M., Cleary, P.P. and McKay, L.L. (Eds). ASM, Washington, DC
    • Malke, H. and Ferretti, J.J. (1991) Expression and properties of hybrid streptokinases extended by N-terminal plasminogen kringle domains. In: Dunny, G.M., Cleary, P.P. and McKay, L.L. (Eds), Genetics and Molecular Biology of Streptococci, Lactococci and Enterococci. ASM, Washington, DC, pp. 184-189.
    • (1991) Genetics and Molecular Biology of Streptococci, Lactococci and Enterococci , pp. 184-189
    • Malke, H.1    Ferretti, J.J.2
  • 19
    • 0025811523 scopus 로고
    • High level heterologous expression in E. Coli using the anaerobically-activated nirB promoter
    • Oxer, M.D., Bentley, C.M., Doyle, J.G., Peakmam, T.C., Charles, I.G. and Makoff, A.J. (1991) High level heterologous expression in E. coli using the anaerobically-activated nirB promoter. Nucleic Acids Res. 19, 2889-2892.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 2889-2892
    • Oxer, M.D.1    Bentley, C.M.2    Doyle, J.G.3    Peakmam, T.C.4    Charles, I.G.5    Makoff, A.J.6
  • 20
    • 0026528230 scopus 로고
    • v fragments with high avidity in Escherichia coli
    • v fragments with high avidity in Escherichia coli. Biochemistry 31, 1579-1584.
    • (1992) Biochemistry , vol.31 , pp. 1579-1584
    • Pack, P.1    Plückthun, A.2
  • 21
    • 0027442660 scopus 로고
    • Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli
    • Pack, P., Kujau, M., Schroeckh, V., Knüpfer, U., Wenderoth, R., Riesenberg, D. and Pluckthun, A. (1993) Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli. Bio/Technology 11, 1271-1277.
    • (1993) Bio/Technology , vol.11 , pp. 1271-1277
    • Pack, P.1    Kujau, M.2    Schroeckh, V.3    Knüpfer, U.4    Wenderoth, R.5    Riesenberg, D.6    Pluckthun, A.7
  • 22
    • 0002014410 scopus 로고
    • Model aided on-line glucose monitoring for computer-controlled high cell density fermentations
    • Munack, A. and Schügerl, K. (Eds). IFAC Publications, Elsevier, Amsterdam
    • Pfaff, M., Wagner, E., Wenderoth, R., Knüpfer, U., Guthke, R. and Riesenberg, D. (1995) Model aided on-line glucose monitoring for computer-controlled high cell density fermentations. In: Munack, A. and Schügerl, K. (Eds), Abstracts book of the 6th International Conference on Computer Applications in Biotechnology. IFAC Publications, Elsevier, Amsterdam, pp. 6-11.
    • (1995) 6th International Conference on Computer Applications in Biotechnology , pp. 6-11
    • Pfaff, M.1    Wagner, E.2    Wenderoth, R.3    Knüpfer, U.4    Guthke, R.5    Riesenberg, D.6
  • 23
    • 0026099154 scopus 로고
    • Induction of recombinant gene expression in Escherichia coli using alkaline pH shift
    • Poindexter, K. and Gayle III, R.B. (1991) Induction of recombinant gene expression in Escherichia coli using alkaline pH shift. Gene 97, 125-130.
    • (1991) Gene , vol.97 , pp. 125-130
    • Poindexter, K.1    Gayle R.B. III2
  • 24
    • 0026677709 scopus 로고
    • Identification and characterization of novel low-temperature-inducible promoters of Escherichia coli
    • Qoronfleh, M.W., Debouck, C. and Keller, J. (1992) Identification and characterization of novel low-temperature-inducible promoters of Escherichia coli. J. Bacteriol. 174, 7902-7909.
    • (1992) J. Bacteriol. , vol.174 , pp. 7902-7909
    • Qoronfleh, M.W.1    Debouck, C.2    Keller, J.3
  • 25
    • 0022446209 scopus 로고
    • Transcription of glnA in E. Coli is stimulated by activator bound to sites far from the promoter
    • Reitzer, L.J. and Magasanik, B. (1986) Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter. Cell 45, 785-792.
    • (1986) Cell , vol.45 , pp. 785-792
    • Reitzer, L.J.1    Magasanik, B.2
  • 26
    • 0001669793 scopus 로고
    • Ammonia assimilation and the biosynthesis of glutamine, glutamate, aspartate, asparagine, L-alanine and D-alanine
    • Neidhardt, F.C., Ingraham, J.L., Low, K.B., Magasanik, B., Schaechter, M. and Umbarger, H.E. (Eds). ASM, Washington, DC
    • Reitzer, L.J. and Magasanik, B. (1987) Ammonia assimilation and the biosynthesis of glutamine, glutamate, aspartate, asparagine, L-alanine and D-alanine. In: Neidhardt, F.C., Ingraham, J.L., Low, K.B., Magasanik, B., Schaechter, M. and Umbarger, H.E. (Eds), Escherichia coli and Salmonella typhimurium Cellular and Molecular Biology. ASM, Washington, DC, pp. 302-320.
    • (1987) Escherichia Coli and Salmonella Typhimurium Cellular and Molecular Biology , pp. 302-320
    • Reitzer, L.J.1    Magasanik, B.2
  • 28
    • 0023254924 scopus 로고
    • Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region
    • Schauder, B., Blöcker, H., Frank, R. and McCarthy, J.E.G. (1987) Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region. Gene 52, 279-283.
    • (1987) Gene , vol.52 , pp. 279-283
    • Schauder, B.1    Blöcker, H.2    Frank, R.3    McCarthy, J.E.G.4
  • 29
    • 0016415604 scopus 로고
    • Chloramphenicol acetyltransferase from chloramphenicol-resistant bacteria
    • Hash, J.H. (Ed.). Academic Press, New York
    • Shaw, W.V. (1975) Chloramphenicol acetyltransferase from chloramphenicol-resistant bacteria. In: Hash, J.H. (Ed.), Methods in Enzymology, Vol. XLIII. Academic Press, New York, pp. 737-755.
    • (1975) Methods in Enzymology , vol.43 , pp. 737-755
    • Shaw, W.V.1
  • 30
    • 0028831325 scopus 로고
    • Betaine modulates intracellular thiol and potassium levels in Escherichia coli in medium with high osmolarity and alkaline pH
    • Smirnova, G. and Oktyabrsky, O. (1995) Betaine modulates intracellular thiol and potassium levels in Escherichia coli in medium with high osmolarity and alkaline pH. Arch. Microbiol. 163, 76-78.
    • (1995) Arch. Microbiol. , vol.163 , pp. 76-78
    • Smirnova, G.1    Oktyabrsky, O.2
  • 31
    • 0015239538 scopus 로고
    • Genetic and metabolic control of enzymes responsible for histidine degradation in Salmonella typhimurium
    • Smith, G.R., Halpern, Y.S. and Magasanik, B. (1971) Genetic and metabolic control of enzymes responsible for histidine degradation in Salmonella typhimurium. J. Biol. Chem. 246, 3320-3329.
    • (1971) J. Biol. Chem. , vol.246 , pp. 3320-3329
    • Smith, G.R.1    Halpern, Y.S.2    Magasanik, B.3
  • 32
    • 0025353465 scopus 로고
    • A novel phosphate-regulated expression vector in Escherichia coli
    • Su, T.-Z., Schweizer, H. and Oxender, D.L. (1990) A novel phosphate-regulated expression vector in Escherichia coli. Gene 90, 129-133.
    • (1990) Gene , vol.90 , pp. 129-133
    • Su, T.-Z.1    Schweizer, H.2    Oxender, D.L.3
  • 33
    • 0026582495 scopus 로고
    • A pH-regulated promoter for the expression of recombinant proteins in Escherichia coli
    • Tolentino, G.J., Meng, S.-Y., Bennett, G.N. and San, K.-Y. (1992) A pH-regulated promoter for the expression of recombinant proteins in Escherichia coli. Biotechnol. Lett. 14, 157-162.
    • (1992) Biotechnol. Lett. , vol.14 , pp. 157-162
    • Tolentino, G.J.1    Meng, S.-Y.2    Bennett, G.N.3    San, K.-Y.4
  • 34
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 35
    • 0021037506 scopus 로고
    • The use of alkaline-phosphatase-conjugated second antibody for the visualization of electrophoretically separated proteins recognized by monoclonal antibodies
    • Turner, B.M. (1983) The use of alkaline-phosphatase-conjugated second antibody for the visualization of electrophoretically separated proteins recognized by monoclonal antibodies. J. Immunol. Methods 63, 1-6.
    • (1983) J. Immunol. Methods , vol.63 , pp. 1-6
    • Turner, B.M.1
  • 36
    • 11944271431 scopus 로고
    • Automatic aseptic sampling of fermentation broth
    • Webb, C., Dean, J.F. and Marshall, R.D. (1990) Automatic aseptic sampling of fermentation broth. Bio/Technology 8, 926-928.
    • (1990) Bio/Technology , vol.8 , pp. 926-928
    • Webb, C.1    Dean, J.F.2    Marshall, R.D.3
  • 37
    • 85030277128 scopus 로고
    • Induction of alkane oxidation genes in recombinant Escherichia coli. The alk promoter is induced by a wide variety of apolar effectors
    • Wubbolts, M.G. (Ed.), Xylene and Alkane Mono-oxygenases from Pseudomonas putida. Proefschrift Rijksuniversiteit Groningen
    • Wubbolts, M.G., Kok, M., Staijen, I.E., Marijnisse, M.J.G.M. and Witholt, B. (1994) Induction of alkane oxidation genes in recombinant Escherichia coli. The alk promoter is induced by a wide variety of apolar effectors. In: Wubbolts, M.G. (Ed.), Xylene and Alkane Mono-oxygenases from Pseudomonas putida. Genetics, Regulated Expression and Utilization in the Synthesis of Optically Active Synthons. Proefschrift Rijksuniversiteit Groningen, pp. 115-128.
    • (1994) Genetics, Regulated Expression and Utilization in the Synthesis of Optically Active Synthons , pp. 115-128
    • Wubbolts, M.G.1    Kok, M.2    Staijen, I.E.3    Marijnisse, M.J.G.M.4    Witholt, B.5
  • 38
    • 0027761471 scopus 로고
    • A versatile and high repressible Escherichia coli expression system based on invertible promoters: Expression of a gene encoding a toxic product
    • Wülfing, C. and Plückthun, A. (1993) A versatile and high repressible Escherichia coli expression system based on invertible promoters: expression of a gene encoding a toxic product. Gene 136, 199-203.
    • (1993) Gene , vol.136 , pp. 199-203
    • Wülfing, C.1    Plückthun, A.2


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