Synthesis and activity of staurosporine analogs with a lactone functionality

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 16, 1996, Pages 1893-1896

  Yamada, Rintaro ^a   Fukuda, Koichiro ^a   Kawanishi, Masashi ^a   Ohmori, Yutaka ^a   Nasu, Makoto ^a   Seto, Minoru ^a   Sasaki, Yasuharu ^a   Sunazuka, Toshiaki ^b   Zhuorong, Li ^b   Funato, Nobuyuki ^b   Iguchi, Mieko ^b   Harigaya, Yoshihiro ^b   Iwai, Yuzuru ^b   Omura, Satoshi ^b  

^a ASAHI CHEMICAL INDUSTRY CO   (Japan)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE C; STAUROSPORINE; STAUROSPORINE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; GUINEA PIG; NONHUMAN; REACTION ANALYSIS; SMOOTH MUSCLE CONTRACTION; THROMBOCYTE AGGREGATION;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0030594971     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00343-5     Document Type: Article

References (11)

1. 1. Omura, S.; Iwai, Y.; Hirano, A.; Nakagawa, A.; Awaya, J.; Tsuchiya, H.; Takahashi, Y.; Masuma, R. J. Antibiotics 1977, 30, 275.
2. 2. Tamaoki, T.; Nomoto, H.; Takahashi, I.; Kato, Y.; Morimoto, M.; Tomita, F. Biochem. Biophys. Res. Commun. 1986, 135, 397.
3. 3. Omura, S.; Iwai, Y. Hakko to Kougyo 1979, 37, 223.
4. 4. Sasaki, Y.; Seto, M.; Komatsu, K.; Omura, S. Eur. J. Pharmacol. 1991, 202, 367.
5. 5. Okazaki, T.; Kato, Y.; Mochizuki, T.; Tashima, M.; Sawada, H.; Uchino, H. Exp. Hematol. 1988, 16, 42.
6. 6. Matsumoto, H.; Sasaki, Y. Biochem. Biophys. Res. Commun. 1989, 158, 105.
7. 7. Omura, S.; Sasaki, Y.; Iwai, Y.; Takeshima, H. J. Antibiotics 1995, 48, 535.
8. 8. Windholz, T. B.; Johnston, D. B. R. Tetrahedron Lett. 1967, 27, 2555.
9. 9. Magnus, P. D.; Sear, N. L. J. Org. Chem. 1973, 38, 4243.
10. 10. Tangen, O.; Berman, H. J.; Marfey, P. Tromb. Diath. Haemorrth. 1971, 25, 269.
11. 11. Asano, M.; Matsunaga, K.; Miura, M.; Ito, K. M.; Seto, M.; Sakurada, K.; Nagumo, H.; Sasaki, S.; Ito. K. Eur. J. Pharmacol. 1995, 294, 693.