Synthesis and biological evaluation of 4-alkoxy substituted trinems. Part 1

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 16, 1996, Pages 2019-2024

  Andreotti, Daniele ^a   Biondi, Stefano ^a   Di Fabio, Romano ^a   Donati, Daniele ^a   Piga, Elisabetta ^a   Rossi, Tino ^a  

^a GSK   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; IMIPENEM; SANFETRINEM; TRINEM DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 0030594970     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00359-9     Document Type: Article

References (18)

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18. 5 CFU/ml. The MIC was defined as the lowest drug concentration that resulted in no visible growth after 20 hours for aerobes and 48 hours for anaerobes of incubation at 37°C . National Committee for Clinical Laboratory Standards. 1990. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; Approved Standard. NCCLS M7-A2, 10, N 8, Villanova, PA, USA. National Committee for Clinical Laboratory Standards. 1990. Methods for antimicrobial susceptibility of anaerobic bacteria. Approved Standard. NCCLS M11-A2, 10, N 15, Villanova, PA, USA.