Enhancement of tamoxifen-induced E-cadherin function by Ca2+ channel antagonists in human breast cancer MCF7/6 cells

European Journal of Pharmacology

Volumn 317, Issue 2-3, 1996, Pages 413-416

  Charlier, Corinne ^a   Bruyneel, Eric ^b   Lechanteur, Chantal ^a   Bracke, Marc ^b   Mareel, Marc ^b   Castronovo, Vincent ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Adhesion; Ca2+ channel antagonist; E cadherin; MCF7 6; Tamoxifen

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; TAMOXIFEN; UVOMORULIN; VERAPAMIL;

ADHESION; ARTICLE; BREAST CANCER; CELL AGGREGATION; CONCENTRATION RESPONSE; DRUG MECHANISM; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; CADHERINS; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CELL AGGREGATION; HUMANS; NIFEDIPINE; TAMOXIFEN; TUMOR CELLS, CULTURED; VERAPAMIL;

EID: 0030593908     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00816-3     Document Type: Article

References (16)

1. Antoniotti, S., P. Maggiora, C. Dati and M. De Bortoli, 1992, Tamoxifen up-regulates cerb-B2 expression in oestrogen-responsive breast cancer cells in vitro, Eur. J. Cancer 28, 318.
2. Baker, V.A., J.R. Puddefoot, S. Marsigliante, S. Baker, A.W. Goode and G.P. Vinson, 1992, Oestrogen receptors isoforms, their distribution and relation to progesterone receptor level in breast cancer samples, Br. J. Cancer 66, 1083.
3. Bracke, M.E., C. Charlier, E.A. Bruyneel, C. Labit, M.M. Mareel and V. Castronovo, 1994, Tamoxifen restores the E-cadherin function in human breast cancer MCF7/6 cells and suppresses their invasive phenotype, Cancer Res. 54, 4607.
4. Castoria, G., A. Migliaccio, E. Nola and F. Auricchio, 1988, In vitro interaction of oestradiol receptor with Ca-calmodulin, Mol. Endocrinol. 2, 167.
5. Charlier, C., C. Colin, M.P. Merville, J. Gielen, R. Lambotte, G. Plomteux and V. Castronovo, 1994, Le tamoxifène dans le traitement du cancer du sein, J. Gynécol. Obstét. Biol. Reprod. 23, 751.
6. Charlier, C., A. Chariot, N. Antoine, M.P. Merville, J. Gielen and V. Castronovo, 1995, Tamoxifen and its active metabolite inhibit growth of estrogen receptor-negative MDA-MB435 cells, Biochem. Pharmacol. 49, 351.
7. Coezy, E., J.L. Borgna and H. Rochefort, 1982, Tamoxifen and metabolites in MCF7 cells: correlation between binding to estrogen receptor and inhibition of cell growth, Cancer Res. 42, 317.
8. Fisher, B., J. Costantino, C. Redmond, R. Poisson, D. Bowman, J. Couture, V.D. Nikolay, N. Wolmark, D.L. Wickerman, E.R. Fisher, R. Margolese, A. Robidoux, H. Shibata, J. Terz, A.H.G. Paterson, M.I. Feldman, W. Farrar, J. Evans, H.L. Lickley and M. Ketner, 1989, A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor positive tumors, New Engl. J. Med. 320, 479.
9. Fuqua, S.A.W., G.C. Chamness and W.L. McGuire, 1993, Estrogen receptor mutations in breast cancer, J. Cell. Biochem. 51, 135.
10. Gupta, V., N. Kamath, G.T. Tkalcevic and S.V. Singh, 1994, Potentiation of tamoxifen activity by verapamil in a human breast cancer cell line, Biochem. Pharmacol. 47, 1701.
11. Jeng, M.H., P. Ten Dijke, K.K. Iwata and V.C. Jordan, 1993, Regulation of the levels of three transforming growth factor β mRNAs by estrogen and their effects on the proliferation of human breast cancer cells, Mol. Cell. Endocrinol. 97, 115.
12. Osborne, C.K., D.H. Boldt, G.M. Clark and J.M. Trent, 1983, Effects of tamoxifen on human breast cancer cell cycle kinetics: accumulation of cells in early G1 phase, Cancer Res. 43, 3583.
13. Shapiro, L., A.M. Fannon, P.D. Kwong, M.S. Lehmann, G. Grübel, J.-F. Legrand, J. Als-Nielsen, D.R. Colman and W.A. Hendrickson, 1995, Structural basis of cell-cell adhesion by cadherins, Nature 374, 327.
14. Soule, H.D., J. Vazquez, A. Long, S. Albert and M. Brennan, 1973, A human cell line of a pleural effusion derived from a breast carcinoma, J. Natl. Cancer Inst. 51, 1409.
15. Strobl, J.S., V.A. Peterson and K.A. Woodfork, 1994, A survey of human breast cancer sensitivity to growth inhibition by calmodulin antagonists in tissue culture, Mol. Endocrinol. 2, 167.
16. Wiseman, H., M. Cannon, H.R. Arnstein and B. Halliwell, 1993, Tamoxifen inhibits lipid peroxidation in cardiac microsomes, Biochem. Pharmacol. 45, 1851.