Synthesis of phosphinic acid transition state analogues for the reaction catalysed by kynureninase

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 22, 1996, Pages 2643-2646

  Ross, Fiona C ^a   Botting, Nigel P ^a   Leeson, Paul D ^b,c  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^c Wyeth Ayerst   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KYNURENINASE; KYNURENINE; KYNURENINE DERIVATIVE; PHOSPHINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; PSEUDOMONAS FLUORESCENS; STRUCTURE ACTIVITY RELATION;

PSEUDOMONAS; PSEUDOMONAS FLUORESCENS;

EID: 0030593882     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00483-0     Document Type: Article

References (12)

1. 1. Soda, K.; Tanizawa K.; Adv. Enzymol., 1979, 49, 1-40.
2. 2. Stone, T. W.; Connick, J. H.; Neuroscience, 1985, 15, 597-615.
3. 3. Lipton, S. A.; Trends in Neurosciences, 1992, 15, 75-79.
4. 4. Botting, N. P.; Chem. Soc. Rev., 1995, 24, 401-412.
5. 5. Tanizawa, K.; Soda, K.; J. Biochem., 1979, 86, 1199-1209.
6. 6. Arnold, L. D.; Kalantar, T.; Vederas, J. D.; J. Am. Chem. Soc., 1985, 107, 7105-7109.
7. +, 12%).
8. 8. Hayaishi, O.; Stanier, R. Y.; J. Biol. Chem., 1952, 195, 735-740.
9. +, 100%).
10. 10. McLeod, D. A.; Brinkworth, R. I.; Ashley, J. A.; Janda, K. D.; Wirsching, P.; Bioorg. Med. Chem. Lett., 1991, 1, 653-658.
11. 11. Phillips, R. S.; Dua, R. K.; J. Am. Chem. Soc., 1991, 113, 7385-7397.
12. 12. Dua, R. K.; Taylor, E. W.; Phillips, R. S.; J. Am. Chem. Soc., 1993, 115, 1264-1270.