Synthesis and biological evaluation of pyrido[2,3-b]pyrazine and pyrido[2,3-b]pyrazine-N-oxide as selective glycine antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 22, 1996, Pages 2749-2754

  Cugola, Alfredo ^a   Donati, Daniele ^a   Guarneri, M ^c   Micheli, Fabrizio ^a   Missio, Andrea ^a   Pecunioso, Angelo ^a   Reggiani, Angelo ^a   Tarzia, G ^b   Zanirato, V ^c  

^a GSK   (Italy)

^b UNIVERSITY OF URBINO   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PYRAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDO[2,3 B]PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BRAIN; BRAIN ISCHEMIA; CONTROLLED STUDY; CONVULSION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; RAT;

ANIMALIA;

EID: 0030593876     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00492-1     Document Type: Article

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