Biotransformation of allylically activated (E,E)-cyclodeca-1,6-dienols by Cichorium intybus

Tetrahedron

Volumn 52, Issue 34, 1996, Pages 11273-11280

  Piet, Dennis P ^a   Franssen, Maurice C R ^a   De Groot, Aede ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SESQUITERPENE LACTONE;

ARTICLE; BIOSYNTHESIS; CHIRALITY; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; PRIORITY JOURNAL; REACTION ANALYSIS;

CICHORIUM INTYBUS; STAPHYLOCOCCUS PHAGE 3A;

EID: 0030593706     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(96)00653-9     Document Type: Article

References (22)

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12. 12. Acid-induced cyclisation reactions in an aqueous environment also gave mixtures of 1,5-and 1,7-cyclisation products. Through these cyclisations, samples were obtained for NMR studies (see the experimental part).
13. 13. This form of anchimeric assistance is very common in norbornene systems. For examples see: Winstein S. and Shatvatsy M. (1956) J. Am. Chem. Soc. 78, 592 and Goering H.L. and Closson W.D. (1961) J. Am. Chem. Soc. 83, 3511.
14. This form of anchimeric assistance is very common in norbornene systems. For examples see: Winstein S. and Shatvatsy M. (1956) J. Am. Chem. Soc. 78, 592 and Goering H.L. and Closson W.D. (1961) J. Am. Chem. Soc. 83, 3511.
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19. 18. Piet D.P, Orru R.V.A., Jenniskens L.H.D., van der Haar C., van Beek T.A., Franssen M.C.R., Wijnberg J.B.P.A. and de Groot Ae. (1996) Chem. Pharm. Bull., accepted.
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21. 20. Preliminary studies on the purification of the FPP-cyclising enzyme from chicory revealed that FPP was transformed into germacrene A. This work was performed in collaboration with AB-DLO, Wageningen; Piet D.P. (1996) Transannular Cyclisation Reactions of the Germacrane System Mediated by Enzymes from Cichorium intybus, PhD.-thesis, Wageningen Agricultural University.
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