Methylenedioxymethamphetamine-induced inhibition of neuronal firing in the nucleus accumbens is mediated by both serotonin and dopamine

Neuroscience

Volumn 74, Issue 2, 1996, Pages 469-481

  Obradovic, T ^a   Imel, K M ^a   White, S R ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

dopamine; drug abuse; MDMA; nucleus accumbens; serotonin; ventral striatum

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3,4 METHYLENEDIOXYAMPHETAMINE; DOPAMINE; FLUOXETINE; GLUTAMIC ACID; KETANSERIN; METHYSERGIDE; METIROSINE; METITEPINE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; OXIDOPAMINE; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DRUG ABUSE; MALE; MICROIONTOPHORESIS; MOOD; NERVE CELL EXCITABILITY; NERVE CELL INHIBITION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SEROTONIN UPTAKE;

EID: 0030593436     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00135-2     Document Type: Article

References (77)

1. 3H]-(S)-zacopride in the forebrain of the rat. Neuropharmacology. 29:1990;1037-1045.
2. Benloucif S., Galloway M. P. Facilitation of dopamine release in vivo by serotonin agonists: studies with microdialysis. Eur. J. Pharmac. 200:1991;1-8.
3. Berger U. V., Gu X. F., Azmitia E. C. The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine. Eur. J. Pharmac. 215:1992;153-160.
4. 3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference. Pharmac. Biochem. Behav. 39:1991;509-512.
5. 3 receptors in rat striatum. J. Pharmac. exp. Ther. 251:1989;803-809.
6. Boeijinga P. H., Pennartz C. M. A., Lopes da Silva F. H. Paired-pulse facilitation in the nucleus accumbens following stimulation of subicular inputs in the rat. Neuroscience. 35:1990;301-311.
7. 1F receptor messenger RNA in rodent and primate brain. Neuropharmacology. 33:1994;367-386.
8. 1-like receptors mediate hyperactivity in rats induced by 3,4-methylenedioxymethamphetamine. Neuropsychopharmacology. 7:1992;113-127.
9. 3 receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens. Brain Res. 543:1991;354-357.
10. Cregg M. T., Tracey J. A. Ecstasy abuse in Ireland. Ir. med. J. 86:1993;118-120.
11. Creighton F. J., Black D. L., Hyde C. E. Ecstasy psychosis and flashbacks. Br. J. Psychiat. 159:1991;713-715.
12. Cuomo M. J., Dyment P. G., Gammino V. M. Increasing use of "ecstasy" (MDMA) and other hallucinogens on a college campus. J. Am. Coll. Health. 42:1994;271-274.
13. DiChiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. natn. Acad. Sci. U.S.A. 85:1988;5274-5278.
14. Fitzgerald J. L., Reid J. J. Effects of methylenedioxymethamphetamine on the release of monoamines from rat brain slices. Eur. J. Pharmac. 191:1990;217-220.
15. 1A receptor. Eur. J. Pharmac. 237:1993;283-291.
16. Fuller T. A., Russchen F. T., Price J. L. Sources of presumptive glutamergic/aspartergic afferents to the rat ventral striatopallidal region. J. comp. Neurol. 258:1987;317-338.
17. Galloway M. P., Suchowski C. S., Keegan M. J., Hjorth S. Local infusion of the selective 5HT-1b agonist CP-93,129 facilitates striatal dopamine release in vivo. Synapse. 15:1993;90-92.
18. 2 serotonin receptors. J. med. Chem. 31:1988;5-7.
19. Gough B., Ali S. F., Slikker W., Holson R. R. Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate. Pharmac. Biochem. Behav. 39:1991;619-623.
20. Hekmatpanah C. R., Peroutka S. J. 5-Hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine releasing effects of 3,4-methylenedioxymethamphetamine and related agent. Eur. J. Pharmac. 177:1990;95-98.
21. Horne A. L., Woodruff G. N., Kemp J. A. Synaptic potentials mediated by excitatory amino acid receptors in the nucleus accumbens of the rat, in vitro. Neuropharmacology. 29:1990;917-921.
22. 1 receptor stimulation. J. Neurosci. 10:1990;2318-2329.
23. 2 binding profiles of the serotonergic agents α-methylserotonin and 2-methylserotonin. J. med. Chem. 33:1990;755-758.
24. 3H]dopamine via reversal of the dopamine transporter in rat striatum and nucleus accumbens: a comparison with release elicited by potassium, N-methyl-D-aspartic acid, glutamic acid and D-amphetamine. J. Pharmac. exp. Ther. 262:1992;356-364.
25. 3H-BIMU-1. Neuropharmacology. 33:1994;1027-1038.
26. 2 receptor blockade to study serotonin-induced pathology. Trends pharmac. Sci. 4:1983;198-206.
27. 3H-dopamine release from superfused rat brain slices. Eur. J. Pharmac. 132:1986;269-276.
28. Kelland M. D., Freeman A. S., Chiodo L. A. (±)-3,4-Methylenedioxymethamphetamine-induced changes in the basal activity and pharmacological responsiveness of nigrostriatal dopamine neurons. Eur. J. Pharmac. 169:1989;11-21.
29. 1A receptor antagonist. Brain Res. 673:1995;217-225.
30. 3 receptors in the rat brain using radioligand binding. Nature. 330:1987;746-748.
31. Koch S., Galloway M. P. Fluoxetine and (+)-MDMA-induced dopamine release in vivo: the role of endogenous serotonin. Soc. Neurosci. Abstr. 20:1994;1558.
32. Koob G. F. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends pharmac. Sci. 13:1992;177-184.
33. Martin G. R., Humphrey P. P. A. Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature. Neuropharmacology. 33:1994;261-273.
34. 2 binding sites with those of serotonin autoreceptors which modulate serotonin release. Naunyn-Schmiedeberg's Arch. Pharmac. 321:1982;165-170.
35. Matthews R. T., Champney T. H., Frye G. D. Effects of (±)3,4-methylenedioxymethamphetamine (MDMA) on brain dopaminergic activity in rats. Pharmac. Biochem. Behav. 33:1989;741-747.
36. McGuire P. K., Cope H., Fahy T. A. Diversity of psychopathology associated with use of 3,4-methylenedioxymethamphetamine ("Ecstasy"). Br. J. Psychiat. 165:1994;391-395.
37. Mengod G., Nguyen H., Le H., Waeber C., Lubbert H., Palacios J. M. The distribution and cellular localization of the serotonin 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry: comparison with receptor binding distribution. Neuroscience. 35:1990;577-591.
38. 2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites. Brain Res. 524:1990;139-143.
39. Meredith G. E., Blank B., Groenewegen H. J. The distribution and compartmental organization of the cholinergic neurons in the nucleus accumbens of the rat. Neuroscience. 31:1989;327-345.
40. Middlemiss D. N., Fozard J. R. 8-Hydroxy-2-(dipropylamino)-tetralin discriminates between subtypes of the 5HT recognition site. Eur. J. Pharmac. 90:1983;151-153.
41. Nash J. F., Brodkin J. Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors. J. Pharmac. exp. Ther. 259:1991;820-825.
42. Neale R. F., Fallon S. L., Boyar W. C., Wasley J. W. F., Martin L. L., Stone G. A., Glaeser B. S., Sinton C. M., Williams M. Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist. Eur. J. Pharmac. 136:1987;1-9.
43. 3H]-serotonin from rat brain synaptosomes. J. med. Chem. 25:1982;530-535.
44. 2 receptors to decrease potassium conductance in rat nucleus accumbens neurons. J. Physiol., Lond. 417:1989;1-12.
45. Pallanti S., Mazzi D. MDMA (ecstasy) precipitation of panic disorder. Biol. Psychiat. 32:1992;91-95.
46. Pan H. S., Wang R. Y. MDMA: further evidence that its action in the medial prefrontal cortex is mediated by the serotonergic system. Brain Res. 539:1991;332-336.
47. Pan H. S., Wang R. Y. The action of (±)-MDMA on medial prefrontal cortical neurons is mediated through the serotonergic system. Brain Res. 543:1991;56-60.
48. Parsons L. G., Justice J. B. Jr. Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis. Brain Res. 606:1993;195-199.
49. 3 receptors in rat cerebral cortex and nucleus accumbens. Br. J. Pharmac. 103:1991;1790-1794.
50. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, New York.
51. Pazos A., Palacios J. M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res. 346:1985;205-230.
52. Pazos A., Cortes R., Palacios J. M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-1 receptors. Brain Res. 346:1985;231-249.
53. Peroutka S. J. Incidence of recreational use of 3,4-methylenedioxymethamphetamine (Ecstasy) on an undergraduate campus. New Engl. J. Med. 317:1987;1542-1543.
54. Peroutka S. J. 5-Hydroxytryptamine receptor subtypes. A. Rev. Neurosci. 11:1988;45-60.
55. 1A receptor in the rat brain: correlation with receptor binding. J. Neurosci. 12:1992;440-453.
56. 2C receptors. Molec. Brain Res. 23:1994;163-178.
57. Rada P. V., Mark G. P., Hoebel B. G. In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: I. Inhibition by serotonin. Brain Res. 619:1993;98-104.
58. 1B receptor activation mimics behavioral effects of presynaptic serotonin release. Neuropsychopharmacology. 8:1993;201-211.
59. 1A receptor antagonist WAY100135: an in vivo microdialysis study. Eur. J. Pharmac. 239:1993;195-202.
60. 6) receptor: molecular cloning, localization and stimulation of cAMP accumulation. Biochem. biophys. Res. Commun. 193:1993;268-276.
61. Schmidt C. J., Levin J. A., Lovenberg W. In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain. Biochem. Pharmac. 36:1987;747-755.
62. 2 receptors reduces the increase in extracellular concentrations of dopamine produced by amphetamine analogue 3,4-methylenedioxymethamphetamine. J. Neurochem. 62:1994;1382-1389.
63. Sprouse J. S., Bradberry C. W., Roth R. H., Aghajanian G. K. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. Eur. J. Pharmac. 167:1989;375-383.
64. Steele T. D., McCann U. D., Ricaurte G. A. 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): pharmacology and toxicology in animals and humans. Addiction. 89:1994;539-551.
65. Ungerstedt U. 6-Hydroxydopamine induced degeneration of central monoamine neurons. Eur. J. Pharmac. 5:1968;107-110.
66. Van Bockstaele E. J., Pickel V. M. Ultrastructure of serotonin-immunoreactive terminals in the core and shell of the rat nucleus accumbens: cellular substrates for interactions with catecholamine afferents. J. comp. Neurol. 334:1993;603-617.
67. Van Wijngaarden I., Tulp M. Th. M., Soudijn W. The concept of selectivity in 5-HT receptor research. Eur. J. Pharmac. 188:1990;301-312.
68. Voigt M. M., Laurie D. J., Seeburg P. H., Bach A. Molecular cloning and characterization of a rat brain cDNA encoding a 5-hydroxytryptamine 1B receptor. Eur. molec. Biol. Org. J. 10:1991;4017-4023.
69. Walaas I. Biochemical evidence for overlapping neocortical and allocortical glutamate projections to the nucleus accumbens and rostral caudatoputamen in the rat brain. Neuroscience. 3:1981;399-405.
70. White F. J. Comparative effects of LSD and lisuride: clues to specific hallucinogenic drug action. Pharmac. Biochem. Behav. 24:1986;365-379.
71. White F. J., Wang R. Y. Electrophysiological evidence for the existence of both D1 and D2 dopamine receptors in the rat nucleus accumbens. J. Neurosci. 6:1986;274-280.
72. White F. J., Hu X.-T., Henry D. J. Electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies. J. Pharmac. exp. Ther. 266:1993;1075-1084.
73. White S. R., Duffy P., Kalivas P. W. Methylenedioxymethamphetamine depresses glutamate-evoked neuronal firing and increases extracellular levels of dopamine and serotonin in the nucleus accumbens in vivo. Neuroscience. 62:1994;41-50.
74. White S. R., Harris G. C., Imel K. M., Wheaton M. J. Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbnes and caudate/putamen cells are enhanced following cocaine self-administration. Brain Res. 681:1995;167-176.
75. Wong D. T., Bymaster F. P., Horng J. S., Molloy B. B. A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-tri-fluoromethylphenoxy)-N-methyl-3-phenylpropylamine. J. Pharmac. exp. Ther. 193:1975;804-811.
76. Woodruff G. N., McCarthy P. S., Walker R. J. Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain Res. 115:1976;133-242.
77. Yamamoto B. K., Spanos L. J. The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat. Eur. J. Pharmac. 148:1988;195-203.