Central noradrenergic lesioning using anti-DBH-saporin: anatomical findings

Brain Research

Volumn 740, Issue 1-2, 1996, Pages 175-184

  Wrenn, Craige C ^a   Picklo, Matthew J ^b   Lappi, Douglas A ^c   Robertson, David ^d   Wiley, Ronald G ^d,e  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c Advanced Targeting Systems   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

immunotoxin; lesion; locus coeruleus; noradrenaline; rat; saporin

Indexed keywords

DOPAMINE BETA MONOOXYGENASE; IMMUNOTOXIN; SAPORIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; LOCUS CERULEUS; NONHUMAN; NORADRENERGIC NERVE; PRIORITY JOURNAL; RAT;

NON-PROGRAMMATIC;

ADRENERGIC FIBERS; ANIMALS; BRAIN; DOPAMINE BETA-HYDROXYLASE; IMMUNOHISTOCHEMISTRY; IMMUNOTOXINS; N-GLYCOSYL HYDROLASES; NEURAL PATHWAYS; PLANT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030592807     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)00855-4     Document Type: Article

References (31)

1. [1] Armstrong, D.M., Ross, C.A., Pickel, V.M., Joh, T.H. and Reis, D.J., Distribution of dopamine-, noradrenaline-, and adrenaline-containing cell bodies in that rat medulla oblongata: demonstrated by the immunocytochemical localization of catecholamine biosynthetic enzymes, J. Comp. Neurol., 212 (1982) 173-187.
2. [2] Barthelemy, I., Martineau, D., Ong, M., Matsunami, R., Ling, N., Benatti, L., Cavallaro, U., Soria, M. and Lappi, D.A., Expression of saporin, a ribosome-inactivating protein from the plant Saponaria officinalis, in Escherichia coli, J. Biol. Chem., 268 (1993), 6541-6548.
3. [3] Book, A.A., Wiley, R.G. and Schweitzer, J.B., Specificity of 192 IgG-saporin for NGF receptor-positive cholinergic basal forebrain neurons in the rat, Brain Res., 590 (1992) 350-355.
4. [4] Book, A.A., Wiley, R.G. and Schweitzer, J.B., 192 IgG-saporin: I. Specific lethality for cholinergic neurons in the basal forebrain of the rat, J. Neuropathol. Exp. Neurol., 53 (1994) 95-102.
5. [5] Chandler, C.E., Parsons, L.M., Hosang, M. and Shooter, E.M., A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells, J. Biol. Chem., 259 (1984) 6882-6889.
6. [6] Davis, T.L. and Wiley, R.G., Anti-Thy 1 immunotoxin, OX7-saporin, destroys cerebellar Purkinje cells after intraventricular injection in rats, Brain Res., 504 (1989) 216-222.
7. [7] Forno, L.S., The locus coeruleus in Alzheimer's disease, J. Neuropathol. Exp. Neurol., 37 (1978) 614.
8. [8] Forno, L.S., Langston, J.W., DeLanney, L.E., Irwin, I. and Ricaurte, G.A., Locus coeruleus lesions and eosinophilic inclusions in MPTP treated monkeys, Ann. Neurol, 20 (1986) 449-455.
9. [9] Fritschy, J.M. and Grzanna, R., Selective effects of DSP4 on locus coeruleus axons: Are there pharmacologically different types of noradrenergic axons in the central nervous system? Prog. Brain Res., 88 (1991) 257-268.
10. [10] Fritschy, J.M. and Grzanna, R., Experimentally-induced neuron loss in the locus coeruleus of adult rats, Exp. Neurol., 111 (1991) 123-127.
11. [11] Greenfield, J.G. and Bosanquat, F.D., The brain stem lesions in parkinsonism, J. Neurol. Neurosurg. Psychiatry, 16 (1953) 213-226.
12. [12] Hallman, H., Lange, J., Olson, L., Stromberg, I. and Jonsson, G., Neurochemical and histochemical characterization of neurotoxic effects of MPTP on brain catecholamine neurons in the mouse, J. Neurochem., 44 (1985) 117-127.
13. [13] Hallman, H., Sundstrom, E. and Jonsson, G., Effects of the noradrenaline neurotoxin DSP4 on monoamine neurons and their transmitter turnover in rat CNS, J. Neural Transm., 60 (1984) 89-102.
14. [14] Heckers, S., Ohtake, T., Wiley, R.G., Lappi, D.A., Geula, C. and Mesulam, M.-M., Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor, J. Neurosci., 14 (1994) 1271-1289.
15. [15] Heikkila, R.E., Hess, A. and Duvoison, R.C., Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice, Science, 224 (1984) 1451-1453.
16. [16] Hu, S.C., Chang, F.W., Sung, Y.J., Hsu, W.M. and Lee, E.H.Y., The neurotoxic effects of MPTP in the substantia nigra and the locus coeruleus in BALB/c mice, J. Pharmacol. Exp. Ther., 259 (1992) 1379-1387.
17. [17] Javitch, J.A., Uhl, G.R. and Snyder, S.H., Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Characterization and localization of receptor binding sites in rat and human brain, Proc. Natl. Acad. Sci. USA, 81 (1984) 4591-4595.
18. [18] Javitch, J.A., D'Amato, R.J., Stritmatter, S.M, and Snyder, S.H., Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity, Proc. Natl. Acad. Sci. USA, 82 (1985) 2173-2177.
19. [19] Jonsson, G., Fuxe, K., Hokfelt, T. and Goldstein, M., Resistance of phenylethanolamine-n-methyl transferase containing neurons to 6-hydroxydopamine, Med. Biol., 54 (1976) 421-426.
20. [20] Jonsson, G., Hallman, H., Ponzio, F. and Ross, S., DSP4 (N-(chloroetbyl)-N-ethyl-2-bromobenzylamine) - a useful tool for central and peripheral noradrenaline neurons, Eur. J. Pharmacol., 72 (1981) 173-188.
21. [21] Kalia, M., Fuxe, K. and Goldstein, M., Rat medulla oblongata. II. Dopaminergic, noradrenergic (A1 and A2) and adrenergic neurons, nerve fibers, and presumptive terminal processes, J. Comp. Neurol., 233 (1985) 308-332.
22. [22] Kostrzewa, R.M. and Jacobowitz, D.M., Pharmacological actions of 6-OHDA, Pharmacol. Rev., 26 (1974) 199-288.
23. [23] Lappi, D.A., Maher, P., Martineau, D. and Baird, A., The basic fibroblast growth factor-saporin mitotoxin acts through the basic fibroblast growth factor receptor, J. Cell. Physiol, 147 (1991) 17-26.
24. [24] McBride, R.L., Ozment, R.V. and Sutin, J., Neonatal 6-OHDA destroys spinal cord noradrenergic axons from the locus coeruleus, but not those from lateral tegmental groups, J. Comp. Neurol., 235 (1985) 375-383.
25. [25] Picklo, M.J., Wiley, R.G., Lappi, D.A. and Robertson, D., Noradrenergic lesioning with an anti-dopamine β-hydroxylase immunotoxin, Brain Res., 666 (1994) 195-200.
26. [26] Picklo, M.J., Wiley, R.G., Lonce, S., Lappi, D.A. and Robertson, D., Anti-dopamine β-hydroxylase immunotoxin-induced sympathectomy in adult in adults rats, J. Pharmacol. Exp. Ther., 275 (1995) 1003-1010.
27. [27] Strudelska, D.R. and Brimijoin, S., Partial isolation of two classes of dopamine β-hydroxylase-containing particles undergoing rapid axonal transport in rat sciatic nerve, J. Neurochem., 53 (1989) 622-631.
28. [28] Weinshilboum, R.M., Serum dopamine β-hydroxylase, Pharmacol. Rev., 30 (1979) 133-166.
29. 3H)MPTP binding sites in rat brain, Eur. J. Pharmacol., 98 (1984) 453-454.
30. [30] Wiley, R.G., Stirpe, F., Thorpe, P. and Oeltmann, T.N., Neuronotoxic effects of monoclonal anti-Thy 1 antibody (OX7) coupled to the ribosome inactivating protein, saporin, as studied by suicide transport experiments in the rat, Brain Res., 505 (1989) 44-54.
31. [31] Wiley, R.G., Oeltmann, T.N. and Lappi, D.A., Immunolesioning: selective destruction of neurons using immunotoxin to rat NGF receptor, Brain Res., 562 (1991) 149-153.