Overexpression of interleukin-6 in the central nervous system of transgenic mice increases central but not systemic proinflammatory cytokine production

Brain Research

Volumn 740, Issue 1-2, 1996, Pages 239-244

  Di Santo, Elena ^a   Alonzi, Tonino ^b   Fattori, Elena ^b   Poli, Valeria ^b   Ciliberto, Gennaro ^b   Sironi, Marina ^a   Gnocchi, Paola ^c   Ricciardi Castagnoli, Paola ^d   Ghezzi, Pietro ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b IRBM   (Italy)

^c Immunology Department   (Italy)

^d CNR   (Italy)

Author keywords

interleukin 1; interleukin 6; lipopolysaccharide; transgenic mice; tumor necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; GLIOSIS; INFLAMMATION; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; CENTRAL NERVOUS SYSTEM; CYTOKINES; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE; MICE, TRANSGENIC; SPLEEN;

EID: 0030592679     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)00865-7     Document Type: Article

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