The deletion allele of the angiotensin I converting enzyme gene as a genetic susceptibility factor for cognitive impairment

Neuroscience Letters

Volumn 217, Issue 2-3, 1996, Pages 203-205

  Amouyel, Philippe ^a   Richard, Florence ^a   Cottel, Dominique ^a   Amant, Carole ^a   Codron, Valérie ^a   Helbecque, Nicole ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Ageing; Angiotensin converting enzyme; Cognitive impairment; Genetic polymorphism; Renin angiotensin system

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGED; AGING; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0030592548     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)13092-5     Document Type: Article

References (17)

1. [1] Amouyel, P., Cottel, D., Berr, C., Vidal, O. and Brousseau, T., ∈4 Allele of the apolipoprotein E gene is a potent risk factor for cognitive impairment, Neurobiol. Aging., 15 (1994) S43.
2. [2] Arregui, A., Perry, E., Rossor, M. and Tomlinson, B.E., Angiotensin converting enzyme in Alzheimer's disease: increased activity in caudate nucleus and cortical areas, J. Neurochem., 82 (1982) 1490-1492.
3. [3] Barnes, N.M., Cheng, C.H., Costall, B., Naylor, R.J., Williams, T. and Wischik, C.M., Angiotensin converting enzyme density is increased in temporal cortex from patients with Alzheimer's disease, Eur. J. Pharmacol., 20 (1991) 289-292.
4. [4] Breteler, M.M.B., Claus, J.J., Grobbee, D.E. and Hofman, A., Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam study, Br. Med. J., 308 (1994) 1604-1608.
5. [5] Cambien, F., Poirier, O., Lecerf, L., Evans, A., Cambou, J.P., Arveiler, D., Luc, G., Bard, J.M., Bara, L., Ricard, S., Tiret, L., Amouyel, P., Alhenc-Gelas, F. and Soubrier, F., Deletion polymorphism in the gene for angiotensin converting enzyme is a potent risk factor for myocardial infarction, Nature, 359 (1992) 641-644.
6. [6] Costerousse, O., Allegrini, J., Lopez, M. and Alhenc-Gelas, F., Angiotensin I-converting enzyme in the human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes, Biochem. J., 290 (1993) 33-40.
7. [7] Croog, S.H., Levine, S., Testa, M.A., Brown, B., Bulpitt, C.J., Jenkins, C.D., Klerman, G.L. and Williams, G.H., The effects of antihypertensive therapy on the quality of life, N. Engl. J. Med., 314 (1986) 1657-1664.
8. [8] Crum, R.M., Anthony, J.C., Bassett, S.S. and Folstein, M.F., Population-based norms for the Mini-Mental State examination by age and education level, J. Am. Med. Assoc., 269 (1993) 2386-2391.
9. [9] Erdös, E. and Skidgel, R.A., The angiotensin I-converting enzyme, Lab. Invest., 56 (1987) 345-348.
10. [10] Feskens, E., Havekes, L.M., Kalmijn, S., de Kniff, P., Launer, L.J. and Kromhout, D., Apolipoprotein e4 allele and cognitive decline in elderly men, Br. Med. J., 309 (1994) 1202-1206.
11. [11] Fogarty, D.G., Maxwell, A.P., Doherty, C.C., Hugues, A.E. and Nevin, N.C., ACE gene typing, Lancet, 343 (1994) 851.
12. [12] Hixson, J.E. and Vernier, D.T., Restriction isotyping of human apoE by gene amplification and cleavage with Hha I, J. Lipid. Res., 31 (1990) 545-548.
13. [13] Huang, X.C., Richards, E.M. and Sumners, C., Mitogen-activated protein kinases in rat brain neuronal cultures are activated by angiotensin II type 1 receptors and inhibited by angiotensin II type 2 receptors, J. Biol. Chem., 271 (1996) 15635-15641.
14. [14] Rigat, B., Hubert, C., Alhenc-Gelas, F., Cambien, F., Corvol, P. and Soubrier, F., An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half of the variance of serum enzyme levels, J. Clin. Invest., 86 (1990) 1343-1346.
15. [15] Tiret, L., Rigat, B., Visvikis, S., Breda, C., Corvol, P., Cambien, F. and Soubrier, F., Evidence from combined segregation and linkage analysis, that a variant of the angiotensin converting enzyme gene controls plasma ACE levels, Am. J. Hum. Genet., 51 (1992) 197-205.
16. [16] Tunstall-Pedoe, H., Kuulasmaa, K., Amouyel, P., Arveiler, D., Rajakangas, A.M. and Pajak, A., on behalf of the WHO MONICA Project, myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates and case fatality in 38 populations from 21 countries in 4 continents, Circulation, 90 (1994) 583-612.
17. [17] Wright, J.W. and Harding, W., Brain angiotensin receptor subtypes in the control of physiological and behavioral responses, Neurosci. Biobehav. Rev., 18 (1994) 21-53.