Tonic suppression of adrenal AP-1 activity by glucocorticoids

Molecular and Cellular Endocrinology

Volumn 122, Issue 2, 1996, Pages 151-158

  Smith, Martin ^a   Burke, Zoe ^a   Carter, David ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Adrenal; AP 1; Glucocorticoids; JunB; Metyrapone

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; METYRAPONE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR II; TRANSCRIPTION FACTOR IID;

ADRENAL GLAND; ADRENAL MEDULLA; ANIMAL; ARTICLE; DRUG EFFECT; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT;

ADRENAL GLANDS; ADRENAL MEDULLA; ANIMALS; DEXAMETHASONE; GLUCOCORTICOIDS; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; MALE; METYRAPONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR TFIID; TRANSCRIPTION FACTORS, TFII;

EID: 0030592257     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/0303-7207(96)03878-6     Document Type: Article

References (30)

1. Pfahl, M. (1993) Nuclear receptor/AP-1 interaction. Endocr. Rev. 14, 651-658.
2. Diamond, M.I., Miner, J.N., Yoshinaga, S.K. and Yamamoto, K.R. (1990) Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science 249, 1266-1272.
3. Kerppola, T.K., Luk, D. and Curran, T. (1993) Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro. Mol. Cell. Biol. 13, 3782-3793.
4. Schule, R., Rangarajan, P., Kilewer, S., Ransone, L.J., Bolado, J., Yang, N., Verma, I.M. and Evans, R.M. (1990) Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62, 1217-1226.
5. Shemshedini, L., Knauthe, R., Sassone-Corsi, P., Pornon, A. and Gronemeyer, H. (1991) Cell-specific inhibitory and stimulatory effects of Fos and Jun on transcription activation by nuclear receptors. EMBO J. 10, 3839-3849.
6. Yang-Yen, H.-F., Chambard, J.-C., Sun, Y.-L., Smeal, T., Schmidt, T.J., Drouin, J. and Karin, M. (1990) Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein:protein interaction. Cell 62, 1205-1215.
7. Jacobson, L., Sharp, F.R. and Dallman, M.F. (1990) Induction of fos-like immunoreactivity in hypothalamic corticotrophin-releasing factor neurons after adrenalectomy in the rat. Endocrinology 126, 1709-1719.
8. Li, X., Song, L., Kolasa, K. and Jope, R.S. (1992) Adrenalectomy potentiates immediate-early gene expression in rat brain. J. Neurochem. 58, 2330-2333.
9. Autelitano, D.J. (1994) Glucocorticoid regulation of c-fos, c-jun and transcription factor AP-1 in the AtT-20 corticotrope cell. J. Neuroendocrinol. 6, 627-637.
10. Pennypacker, K.R., Hong, J-S., Douglass, J. and Mcmillan, M.K. (1992) Constitutive expression of AP-1 transcription factors in the rat adrenal. J. Biol. Chem. 267, 20148-20152.
11. Wurtmann, R.J. and Axelrod, J. (1965) Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. Science 150, 1464-1465.
12. Inturrisi, C.D., Branch, A.D., Robertson, H.D., Howells, R.D., Franklin, S.O., Shapiro, J.R., Calvano, S.E. and Yoburn, B.C. (1988) Glucocorticoid regulation of enkephalins in cultured rat adrenal medulla. Mol. Endocrinol. 2, 633-640.
13. La Gamma, E.F. and Adler, J.E. (1987) Glucocorticoids regulate adrenal opiate peptides. Mol. Brain Res. 2, 125-130.
14. Carter, D.A. (1994) A daily rhythm of activator protein-1 activity in the rat pineal is dependent upon trans-synaptic induction of JunB. Neuroscience 62, 1267-1278.
15. Ang, H.-L., Carter, D.A. and Murphy, D. (1993) Neuron-specific expression and physiological regulation of bovine vasopressin transgenes in mice. EMBO. J. 12, 2397-2409.
16. Wisden, W., Errington, M.L., Williams, S., Dunnett, S.B., Waters, C., Hitchcock, D., Evan, G., Bliss, T.V.P. and Hunt, S.P. (1990) Differential expression of immediate-early genes in the hippocampus and spinal cord. Neuron 4, 603-614.
17. Andrews, N.C. and Faller, D.V. (1991) A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19, 2499.
18. Herman, J.P., Schafer, M.K.H., Thompson, R.C. and Watson, S.J. (1992). Rapid regulation of corticotropin-releasing hormone gene transcription in vivo. Mol. Endocrinol. 6, 1061-1069.
19. Morgan, J.I. and Curran, T. (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible protooncogenes fos and jun. Annu. Rev. Neurosci. 14, 421-451.
20. Betito, K., Diorio, J., Meaney, M.J. and Boksa, P. (1992) Adrenal phenylethanolamine N-methyltransferase induction in relation to glucocorticoid receptor dynamics: evidence that acute exposure to high cortisol levels is sufficient to induce the enzyme. J. Neurochem. 58, 1853-1862.
21. Imai, T., Seo, H., Murata, Y., Ohno, M., Satoh, Y., Funahashi, H., Takagi, H. and Matsui, N. (1990) Adrenocorticotropin increases expression of c-fos and beta-actin genes in the rat adrenals. Endocrinology 127, 1742-1747.
22. Pelto-Huikko, M., Dagerlind, A., Kononen, J., Lundberg, J.M., Villar, M., Koistinaho, J., Bravo, R. and Hokfelt, T. (1995) Neuronal regulation of c-fos, c-jun, and junB immediate early genes in rat adrenal medulla. J. Neurosci. 15, 1854-1868.
23. Nankova, B., Devlin, D., Kvetnansky, R., Kopin, I.J. and Sabban, E.L. (1993) Repeated immobilization stress increases the binding of c-Fos-like proteins to a rat dopamine beta-hydroxylase promoter enhancer sequence. J. Neurochem. 61, 776-779.
24. Zhu, Y.-S., Brodsky, M., Franklin, S.O., Huang, T. and Inturrisi, C.E. (1993) Metrazole induces the sequential activation of c-fos, proenkephalin, and tyrosine hydroxylase gene expression in the rat adrenal gland: modulation by glucocorticoid and adrenocorticotrophic hormone. Mol. Pharmacol. 44, 328-326.
25. Deng, T. and Karin, M. (1993) JunB differs from c-Jun in its DNA-binding and dimerization domains and represses c-Jun by formation of inactive heterodimers. Genes Dev. 7, 479-490.
26. Schutte, J., Viallet, J., Nau, M., Segal, S., Fedorko, J. and Minna, J. (1989) Jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun. Cell 59, 987-997.
27. Hsu, J.-C., Cressman, D.E. and Taub, R. (1993) Promoter-specific trans-activation and inhibition mediated by junB. Cancer Res. 53, 3789-3794.
28. Baumann, H., Jahreis, G.P., Morella, K.K., Won, K.A., Pruitt, S.C., Jones, V.E. and Prowse, K.R. (1991) Transcriptional regulation through cytokine and glucocorticoid response elements of rat acute phase plasma protein genes by C/EBP and JunB. J. Biol. Chem. 266, 20390-20399.
29. Kawakami, Z., Kitabayashi, I., Matsuoka, T., Gachelin, G. and Yokoyama, K. (1992) Conserved structural motifs among mammalian junB genes. Nucleic Acids Res. 20, 914.
30. Ross, M.E., Evinger, M.J., Hyman, S.E., Carroll, J.M., Mucke, L., Comb, M., Reis, D.J., Joh, T.H. and Goodman, H.M. (1990) Identification of a functional glucocorticoid response element in the phenylethanolamine N-methyltransferase promoter using fusion genes introduced into chromaffin cells in primary culture. J. Neurosci. 10, 520-530.