O-benzyl hydroxyproline as a bioisostere for Phe-Pro: Novel dipeptide thrombin inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 18, 1996, Pages 2225-2230

  Klein, Scott I ^a   Dener, Jeffrey M ^a   Molino, Bruce F ^a   Gardner, Charles J ^a   D'Alisa, Rose ^a   Dunwiddie, Christopher T ^a   Kasiewski, Charles ^a   Leadley, Robert J ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; CHLOROMETHYL KETONE; DEXTRO PHENYLALANYLPROLYLARGININE; DIPEPTIDE; PLASMIN; THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PEPTIDE SYNTHESIS; RAT; STRUCTURE ACTIVITY RELATION; THROMBOSIS;

ANIMALIA;

EID: 0030591692     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00404-0     Document Type: Article

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