Mutations in the amino-terminal domain of the human poly(ADP-ribose) polymerase that affect its catalytic activity but not its DNA binding capacity

FEBS Letters

Volumn 399, Issue 3, 1996, Pages 313-316

  Trucco, Carlotta ^a   Flatter, Eric ^a   Fribourg, Sébastien ^a   De Murcia, Gilbert ^a   Ménissier De Murcia, Josiane ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Colony screening; DNA binding protein; NAD metabolism; Random mutagenesis; Zinc finger

Indexed keywords

DNA BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

AMINO ACID SEQUENCE; ARTICLE; DNA BINDING; ENZYME ANALYSIS; ENZYME CONFORMATION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE METABOLISM; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

CATALYSIS; DNA-BINDING PROTEINS; ESCHERICHIA COLI; HUMANS; MUTAGENESIS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030590844     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(96)01347-6     Document Type: Article

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