-
1
-
-
0027374447
-
Phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy
-
Amlot, P.L., Stone, M.J., Cunningham, D., Fay, J., Newman, R., Collins, R., May, R., McCarthy, M., Richardson, J., Ghetie, V., Ramilo, O., Thorpe, P.E., Uhr, J.W. and Vitetta, E.S. (1993) Phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy. Blood 82, 2624.
-
(1993)
Blood
, vol.82
, pp. 2624
-
-
Amlot, P.L.1
Stone, M.J.2
Cunningham, D.3
Fay, J.4
Newman, R.5
Collins, R.6
May, R.7
McCarthy, M.8
Richardson, J.9
Ghetie, V.10
Ramilo, O.11
Thorpe, P.E.12
Uhr, J.W.13
Vitetta, E.S.14
-
2
-
-
0024151158
-
Prevention of carbohydrate-mediated clearance of ricin -containing immunotoxins by the liver
-
A.E. Frankel (Ed.), Kluwer Academic, Boston, MA
-
Blakey, D.C., and Thorpe, P.E. (1988) Prevention of carbohydrate-mediated clearance of ricin -containing immunotoxins by the liver. In: A.E. Frankel (Ed.), Immunotoxins. Kluwer Academic, Boston, MA, p. 457.
-
(1988)
Immunotoxins
, pp. 457
-
-
Blakey, D.C.1
Thorpe, P.E.2
-
3
-
-
0025114771
-
Diagnosis and management of acute lymphoblastic leukemia
-
Buchanan, G. (1990) Diagnosis and management of acute lymphoblastic leukemia. Hematol. Oncol. Clin. N. Am. 4, 75.
-
(1990)
Hematol. Oncol. Clin. N. Am.
, vol.4
, pp. 75
-
-
Buchanan, G.1
-
4
-
-
0025218751
-
Use of an anti-pan T lymphocyte ricin A chain immunotoxin as targeted immunotherapy in steroid resistant acute graft versus host disease
-
Byers, V.S., Henslee, P.J., Kernan, N., Blazar, B.R., Gingrich, R., Phillips, G.L., LeMaistre, C.R., Gilliland, G., Antin, J.J., Vogelsang, G., Martin, P., Tutschka, P.J., Trown, P., Ackerman, S.K., O'Reilly, R.J. and Scannon, P.J. (1990) Use of an anti-pan T lymphocyte ricin A chain immunotoxin as targeted immunotherapy in steroid resistant acute graft versus host disease. Blood 75, 1426.
-
(1990)
Blood
, vol.75
, pp. 1426
-
-
Byers, V.S.1
Henslee, P.J.2
Kernan, N.3
Blazar, B.R.4
Gingrich, R.5
Phillips, G.L.6
LeMaistre, C.R.7
Gilliland, G.8
Antin, J.J.9
Vogelsang, G.10
Martin, P.11
Tutschka, P.J.12
Trown, P.13
Ackerman, S.K.14
O'Reilly, R.J.15
Scannon, P.J.16
-
5
-
-
0018115212
-
Protein thiolation and reversible protein-protein conjugation
-
Carlsson, J., Drevin, H. and Axen, R. (1978) Protein thiolation and reversible protein-protein conjugation. Biochem. J. 173, 723.
-
(1978)
Biochem. J.
, vol.173
, pp. 723
-
-
Carlsson, J.1
Drevin, H.2
Axen, R.3
-
6
-
-
8044225375
-
Comparison of the therapeutic efficacy of anti-CD7-saporin immunotoxins constructed with one or two saporin moieties per immunotoxin molecule in SCID mice with human T-cell acute leukemia
-
Myrtle Beach, South Carolina
-
Flavell, D.J., Boehm, D.A., Emery, L., Noss, A. and Flavell, S.U. (1995) Comparison of the therapeutic efficacy of anti-CD7-saporin immunotoxins constructed with one or two saporin moieties per immunotoxin molecule in SCID mice with human T-cell acute leukemia [abstract}. Fourth International Symposium on Immunotoxins. Myrtle Beach, South Carolina.
-
(1995)
Fourth International Symposium on Immunotoxins
-
-
Flavell, D.J.1
Boehm, D.A.2
Emery, L.3
Noss, A.4
Flavell, S.U.5
-
7
-
-
0022931519
-
2, and B chains and characterization of their toxicity
-
2, and B chains and characterization of their toxicity. J. Biol. Chem. 261, 5314.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5314
-
-
Fulton, R.J.1
Blakey, D.C.2
Knowles, P.P.3
Uhr, J.W.4
Thorpe, P.E.5
Vitetta, E.S.6
-
8
-
-
0027363391
-
Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains
-
Ghetie, V., Swindel, E., Uhr, J.W. and Vitetta, E.S. (1993) Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains. J. Immunol. Methods 166, 117.
-
(1993)
J. Immunol. Methods
, vol.166
, pp. 117
-
-
Ghetie, V.1
Swindel, E.2
Uhr, J.W.3
Vitetta, E.S.4
-
9
-
-
0026594113
-
Successful treatment of human acute T-cell leukemia in SCID mice using anti-CD7-deglycosylated ricin A-chain immunotoxin DA7
-
Jansen, B., Vallera, D.A., Jaszcz, W.B., Nguyen, D. and Kersey, J.H. (1992) Successful treatment of human acute T-cell leukemia in SCID mice using anti-CD7-deglycosylated ricin A-chain immunotoxin DA7. Cancer Res. 52, 1314.
-
(1992)
Cancer Res.
, vol.52
, pp. 1314
-
-
Jansen, B.1
Vallera, D.A.2
Jaszcz, W.B.3
Nguyen, D.4
Kersey, J.H.5
-
10
-
-
0024477757
-
Ontogeny of T-cell precursors: A model for the initial stages of human T-cell development
-
Haynes, B.F., Denning, S.M, Singer, K.H. and Kurtzberg, J. (1989) Ontogeny of T-cell precursors: A model for the initial stages of human T-cell development. Immunol. Today 10, 87.
-
(1989)
Immunol. Today
, vol.10
, pp. 87
-
-
Haynes, B.F.1
Denning, S.M.2
Singer, K.H.3
Kurtzberg, J.4
-
11
-
-
0013886333
-
Evaluation of survival data in two new rank order statistics arising in its consideration
-
Mantel, N. (1966) Evaluation of survival data in two new rank order statistics arising in its consideration. Cancer Chemother Rep. 50, 163.
-
(1966)
Cancer Chemother Rep.
, vol.50
, pp. 163
-
-
Mantel, N.1
-
12
-
-
0020380627
-
A new solid state reagent to iodinate proteins: Conditions for the efficient labeling of antiserum
-
Markwell, M.A.K. (1982) A new solid state reagent to iodinate proteins: conditions for the efficient labeling of antiserum Anal. Biochem. 125, 427.
-
(1982)
Anal. Biochem.
, vol.125
, pp. 427
-
-
Markwell, M.A.K.1
-
13
-
-
0024330176
-
The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins
-
Myers, D.E., F.M. Uckun, S.E. Swaim and D.A. Vallera (1989) The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins. J. Immunol. Methods 121, 129.
-
(1989)
J. Immunol. Methods
, vol.121
, pp. 129
-
-
Myers, D.E.1
Uckun, F.M.2
Swaim, S.E.3
Vallera, D.A.4
-
14
-
-
0029146577
-
Favorable pharmacodynamic features and superior anti-leukemic activity of B43 (anti-CD19) immunotoxins containing two pokeweed antiviral protein molecules covalently linked to each monoclonal antibody molecule
-
Myers, D.E., Yanishevski, Y., Masson, E., Irvin, J.D., Evans W.E. and Uckun F.M. (1995) Favorable pharmacodynamic features and superior anti-leukemic activity of B43 (anti-CD19) immunotoxins containing two pokeweed antiviral protein molecules covalently linked to each monoclonal antibody molecule. Leukemia Lymphoma 18, 93.
-
(1995)
Leukemia Lymphoma
, vol.18
, pp. 93
-
-
Myers, D.E.1
Yanishevski, Y.2
Masson, E.3
Irvin, J.D.4
Evans, W.E.5
Uckun, F.M.6
-
15
-
-
0017191401
-
An efficient mRNA-dependent translation system from reticulocyte lysates
-
Pelham, H.R. and Jackson, P.J. (1976) An efficient mRNA-dependent translation system from reticulocyte lysates. Eur. J. Biochem. 67, 247.
-
(1976)
Eur. J. Biochem.
, vol.67
, pp. 247
-
-
Pelham, H.R.1
Jackson, P.J.2
-
16
-
-
0025316395
-
Anti-tumor activity of L6-ricin immunotoxin against the H2981-T3 lung adenocarcinoma cell line in vitro and in vivo
-
Schmidberger, H., King, L., Lasky, L.C. and Vallera, D.A. (1990) Anti-tumor activity of L6-ricin immunotoxin against the H2981-T3 lung adenocarcinoma cell line in vitro and in vivo Cancer Res. 50, 3249.
-
(1990)
Cancer Res.
, vol.50
, pp. 3249
-
-
Schmidberger, H.1
King, L.2
Lasky, L.C.3
Vallera, D.A.4
-
17
-
-
0025760632
-
Radiotherapy in mice with Yttrium-90 labeled anti-Ly1 monoclonal antibody: Therapy of the T cell lymphoma EL4
-
Schmidberger, H., Buchsbaum, D.J., Blazar, B.R., Everson, P. and Vallera, D.A. (1991) Radiotherapy in mice with Yttrium-90 labeled anti-Ly1 monoclonal antibody: Therapy of the T cell lymphoma EL4. Cancer Res. 51, 1883.
-
(1991)
Cancer Res.
, vol.51
, pp. 1883
-
-
Schmidberger, H.1
Buchsbaum, D.J.2
Blazar, B.R.3
Everson, P.4
Vallera, D.A.5
-
18
-
-
0023616248
-
Comparison of two anti-thy 1.1-Abrin A-chain immunotoxins prepared with different cross-linking agents: Antitumor effects, in vivo fate, and tumor cell mutants
-
Thorpe, P., Blakey, D., Brown, A., Knowles, P., Knyba, R., Wallace, P., Watson, G. and Wawrzynaczak, E. (1987a) Comparison of two anti-thy 1.1-Abrin A-chain immunotoxins prepared with different cross-linking agents: antitumor effects, in vivo fate, and tumor cell mutants. J. Natl. Cancer Inst. 79, 1101.
-
(1987)
J. Natl. Cancer Inst.
, vol.79
, pp. 1101
-
-
Thorpe, P.1
Blakey, D.2
Brown, A.3
Knowles, P.4
Knyba, R.5
Wallace, P.6
Watson, G.7
Wawrzynaczak, E.8
-
19
-
-
0023554984
-
New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo
-
Thorpe, P., Wallace, P., Knowles, P., Relf, M., Brown, A., Watson, G., Knyba, R., Wawrzynczak, E. and Blakey, D. (1987b) New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo. Cancer Res. 47, 5924.
-
(1987)
Cancer Res.
, vol.47
, pp. 5924
-
-
Thorpe, P.1
Wallace, P.2
Knowles, P.3
Relf, M.4
Brown, A.5
Watson, G.6
Knyba, R.7
Wawrzynczak, E.8
Blakey, D.9
-
20
-
-
0023689869
-
Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A chain and hindered disulfide linkages
-
Thorpe, P.E., Wallace, P.M., Knowles. P.P., Relf, M.G., Brown. A.N.F., Watson, G.J., Blakey, D.C. and Newell, D.R. (1988) Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A chain and hindered disulfide linkages Cancer Res. 48, 6396.
-
(1988)
Cancer Res.
, vol.48
, pp. 6396
-
-
Thorpe, P.E.1
Wallace, P.M.2
Knowles, P.P.3
Relf, M.G.4
Brown, A.N.F.5
Watson, G.J.6
Blakey, D.C.7
Newell, D.R.8
-
21
-
-
0021971392
-
Combined ex vivo treatment with immunotoxins and mafosfamid: A novel immunochemotherapeutic approach for elimination of neoplastic T-cells from autologous marrow grafts
-
Uckun, F.M., Stong, R.C., Youle, R.J. and Vallera, D.A. (1985) Combined ex vivo treatment with immunotoxins and mafosfamid: A novel immunochemotherapeutic approach for elimination of neoplastic T-cells from autologous marrow grafts. J. Immunol. 134, 3504.
-
(1985)
J. Immunol.
, vol.134
, pp. 3504
-
-
Uckun, F.M.1
Stong, R.C.2
Youle, R.J.3
Vallera, D.A.4
-
22
-
-
85030279473
-
Autologous bone marrow transplantation in high risk remission T-lineage ALL using immunotoxins plus 4-HC for marrow purging: I. Application of multiparameter flow cytometry and colony assays for a quantitative analysis of autografts for the presence of residual T-lineage leukemic lymphoid progenitor cells
-
Uckun, F.M., Kersey, J.H., Vallera, D.A., Ledbetter, J.A., Weisdorf, D., Myers, D.E., Haake, R. and Ramsay, N.K.C. (1990) Autologous bone marrow transplantation in high risk remission T-lineage ALL using immunotoxins plus 4-HC for marrow purging: I. Application of multiparameter flow cytometry and colony assays for a quantitative analysis of autografts for the presence of residual T-lineage leukemic lymphoid progenitor cells. Blood 79, 1723.
-
(1990)
Blood
, vol.79
, pp. 1723
-
-
Uckun, F.M.1
Kersey, J.H.2
Vallera, D.A.3
Ledbetter, J.A.4
Weisdorf, D.5
Myers, D.E.6
Haake, R.7
Ramsay, N.K.C.8
-
23
-
-
0028899543
-
Leukemic cell growth in SCID mice as a predictor of relapse in high risk B-lineage acute lymphoblastic leukemia
-
Uckun, F., Sather, H., Reaman, G., Shutter, J., Land, V., Trigg, M., Gunther, R., Chelstrom, L., Bleyer, A. and Gagnon, P. (1995) Leukemic cell growth in SCID mice as a predictor of relapse in high risk B-lineage acute lymphoblastic leukemia. Blood 85, 873.
-
(1995)
Blood
, vol.85
, pp. 873
-
-
Uckun, F.1
Sather, H.2
Reaman, G.3
Shutter, J.4
Land, V.5
Trigg, M.6
Gunther, R.7
Chelstrom, L.8
Bleyer, A.9
Gagnon, P.10
-
24
-
-
0026375173
-
Phase I immunotoxin trial in patients with B-cell lymphoma
-
Vitetta, E.S., Stone, M., Amlot, P., May, R., Till, M., Newman, J., Clark, P., Collins, R., Cunningham, D., Ghetie, V., Uhr, J.W. and Thorpe, P.E. (1991) Phase I immunotoxin trial in patients with B-cell lymphoma. Cancer Res. 51, 4052.
-
(1991)
Cancer Res.
, vol.51
, pp. 4052
-
-
Vitetta, E.S.1
Stone, M.2
Amlot, P.3
May, R.4
Till, M.5
Newman, J.6
Clark, P.7
Collins, R.8
Cunningham, D.9
Ghetie, V.10
Uhr, J.W.11
Thorpe, P.E.12
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