Nicardipine and MK-801 attenuate platelet-activating factor increases following cerebral ischemia-reperfusion in gerbils

Brain Research

Volumn 733, Issue 2, 1996, Pages 203-210

  Nishida, Keiji ^a   Markey, S P ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Bay K8644; Brain ischemia; Ca2+ influx; MK 801; Nicardipine; Platelet activating factor

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL BLOCKING AGENT; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NICARDIPINE; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CALCIUM TRANSPORT; CONTROLLED STUDY; FEMALE; GERBIL; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; THALAMUS;

EID: 0030590430     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00535-5     Document Type: Article

References (50)

1. Alonso F., Gil M.G., Sánchez-Crespo M., Mato J.M. Activation of 1-alkyl-2-lysoglycero-3-phosphocholine. Acetyl-CoA transferase during phagocytosis in human polymorphonuclear leukocytes. J. Biol. Chem. 257:1982;3376-3378.
2. Alps B.J. Drugs acting on calcium channels: potential treatment for ischaemic stroke. Br. J. Clin. Pharmacol. 34:1992;199-206.
3. Alps B.J., Calder C., Hass W.K., Wilson A.D. Comparative protective effects of nicardipine, flunarizine, lidoflazine and nimodipine against ischaemic injury in the hippocampus of the Mongolian gerbil. Br. J. Pharmacol. 93:1988;877-883.
4. Araki T., Kogure K., Nishioka K. Comparative neuroprotective effects of pentobarbital, vinpocetin, flunarizine and ifenprodil on ischemic neuronal damage in the gerbil hippocampus. Res. Exp. Med. 190:1990;19-23.
5. Beneviste H., Drejer J., Schousboe A., Diemer N.H. Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient ischaemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1374.
6. Braquet P., Touqui L., Shen T.Y., Vargaftig B.B. Perspectives in platelet-activating factor research. Pharmacol. Rev. 39:1987;97-145.
7. Buchan A., Pulsinelli W.A. Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia. J. Neurosci. 10:1990;311-316.
8. Chopp M., Chen H., Dereski M.O., Garcia J.H. Mild hypothermic intervention after graded ischemic stress in rats. Stroke. 22:1991;37-43.
9. Clifton G.L., Taft W.C., Blair R.E., Choi S.C., DeLorenzo R.J. Conditions for pharmacologic evaluation in the gerbil model of forebrain ischemia. Stroke. 20:1989;1545-1552.
10. 3H]PY 108-068. J. Neural Transm. 60:1984;169-197.
11. Fleckenstein A. Historical overview. The calcium channel of the heart. Ann. NY Acad. Sci. 522:1988;1-15.
12. Frerichs K.U., Feuerstein G.Z. Platelet-activating factor-key mediator in neuroinjury? Cerebrovasc. Brain Metab. Rev. 2:1990;148-160.
13. Greenberg J.H., Uematsu D., Araki N., Hickey W.F., Reivich M. Cytosolic free calcium during focal cerebral ischemia and the effects of nimodipine on calcium and histologic damage. Stroke. 21((12 Suppl.)):1990;IV72-IV77.
14. Grotta, J.C., Pettigrew, L.C., Lockwood, A.H., Reid, C. and Reich, C., Brain extraction of a calcium channel blocker [published erratum appears in Ann. Neurol. 1987 May; 21(5): 450], Ann. Neurol., 21 (1987) 171-175.
15. Grotta, J.C., Pettigrew, L.C., Lockwood, A.H., Reid, C. and Reich, C., Brain extraction of a calcium channel blocker [published erratum appears in Ann. Neurol. 1987 May; 21(5): 450], Ann. Neurol., 21 (1987) 171-175.
16. Brain Resuscitation Clinical Trial II Study Group A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest. N. Engl. J. Med. 324:1991;1225-1231.
17. Hadani M., Young W., Flamm E.S. Nicardipine reduces calcium accumulation and electrolyte derangements in regional cerebral ischemia in rats. Stroke. 19:1988;1125-1132.
18. Hewitt K., Corbett D. Combined treatment with MK-801 and nicardipine reduces global ischemic damage in the gerbil. Stroke. 23:1992;82-86.
19. Higuchi S., Shiohara Y. Comparative pharmacokunetics of nicardipine hydrochloride: A new vasodilator in various species. Xenobiotica. 10:1980;447-454.
20. Kawamura S., Shirasawa M., Fukasawa H., Yasui N. Attenuated neuropathology by nivaldipine after middle cerebral artery occlusion in rats. Stroke. 22:1991;51-55.
21. 2+ antagonist and protection of the brain against ischemia. Effects of nicardipine on free fatty acid liberation in the ischemic brain in rats. Surg. Neurol. 28:1987;437-440.
22. Kornecki E., Ehrlich H.Y. Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor. Science. 240:1988;1792-1794.
23. Kuwaki T., Satoh H., Ono T., Shibayama F., Yamashita T., Nishimura T. Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins. Stroke. 20:1989;78-83.
24. Li Y., Kawamura S., Yasui N., Shirasawa M., Fukasawa H. Therapeutic effects of nilvadipine on rat focal cerebral ischemia. Exp. Brain Res. 99:1994;1-6.
25. Martin-Moutot N., Seagar M., Couraud F. Subtypes of voltage-sensitive calcium channels in cultured rat brain neurons. Neurosci. Lett. 115:1990;300-306.
26. Miyazawa T., Bonnekoh P., Widmann R., Hossmann K.A. Heating of the brain to maintain normothermia during ischemia aggravates brain injury in the rat. Acta Neuropathol. 85:1993;488-494.
27. Miyazawa T., Hossmann K.A. Temperature effect on ischemic brain injury. No To Shinkei. 46:1994;29-37.
28. 2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils. Brain Res. 613:1993;181-192.
29. Nishida K., Markey S.P. Platelet-activating factor in brain regions following transient ischemia in gerbils. Stroke. 27:1996;514-518.
30. Nowak T.S.J. Localization of 70 kDa stress protein mRNA induction in gerbil brain after ischemia. J. Cereb. Blood Flow Metab. 11:1991;432-439.
31. Nowycky M., Fox A., Tsien R. Three types of neuronal calcium channel with different calcium agonist sensitivity. Nature. 316:1985;440-443.
32. Oberpichler H., Sauer D., Rossberg C., Mennel H.D., Krieglstein J. PAF antagonist ginkgolide B reduces postischemic neuronal damage in rat brain hippocampus. J. Cereb. Blood Flow Metab. 10:1990;133-135.
33. Panetta T., Marcheselli V.L., Braquet P., Spinnewyn B., Bazan N.G. Effects of a platelet activating factor antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: inhibition of ischemia-reperfusion induced cerebral injury. Biochem. Biophys. Res. Commun. 149:1987;580-587.
34. Prehn J.H., Krieglstein J. Platelet-activating factor antagonists reduce excitotoxic damage in cultured neurons from embryonic chick telencephalon and protect the rat hippocampus and neocortex from ischemic injury in vivo. J. Neurosci. Res. 34:1993;179-188.
35. Reedy D., Little J., Carparo J., Sluggy R., Lesser R. Effects of verapamil on acte focal cerebral ischemia. Neurosurgery. 12:1983;272-276.
36. Sauter A., Rudin M. Calcium antagonists reduce the extent of infarction in rat middle cerebral artery occlusion model as determined by quantitative magnetic resonance imaging. Stroke. 17:1986;1228-1234.
37. Schanne F.A., Kane A.B., Young E.E., Farber J.L. Calcium dependence of toxic cell death: a final common pathway. Science. 206:1979;700-702.
38. 2+ channels. Nature. 303:1983;535-537.
39. Shirakura S., Karasawa A., Kubo K. Effect of benidipine hydrochloride (KW-3049), on cerebral ischemia induced by bilateral occlusion of the common carotid arteries in rats. Biol. Pharm. Bull. 16:1993;475-479.
40. Siesjo B.K. Cell damage in the brain: a speculative synthesis. J. Cereb. Blood Flow Metab. 1:1981;155-185.
41. Siesjo B.K., Bengtsson F. Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J. Cereb. Blood Flow Metab. 9:1989;127-140.
42. +] in the hippocampus during recovery from short-term, transient ischemia. J. Cereb. Blood Flow Metab. 12:1992;759-772.
43. Snyder F. Biochemistry of platelet-activating factor: a unique class of biologically active phospholipids. Proc. Soc. Exp. Biol. Med. 190:1989;125-135.
44. Speddings M., Kilpatrick A.T., Alps B.J. Activators and inactivators of calcium channels: effects in the central nervous system. Fundam. Clin. Pharmacol. 3:1989;3s-29s.
45. Spinnewyn B., Blavet N., Clostre F., Bazan N., Braquet P. Involvement of platelet-activating factor (PAF) in cerebral post-ischemic phase in Mongolian gerbils. Prostaglandins. 34:1987;337-349.
46. Takahashi K., Akaike N. Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons. J. Pharmacol. Exp. Ther. 256:1991;169-175.
47. Tomimoto H., Wakita H., Akiguchi I., Kimura J. Protective effect of nicardipine hydrochloride on the evolution of delayed neuronal death - an immunohistochemical study. No To Shinkei. 46:1994;251-256.
48. Warner M.A., Neill K.H., Nadler J.V., Crain B.J. Regionally selective effects of NMDA receptor antagonists against ischemic brain damage in the gerbil. J. Cereb. Blood Flow Metab. 11:1991;600-610.
49. Wong E.H.F., Kemp J.A., Priestley T., Knight A.R., Woodruff G.N., Iversen L.L. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc. Natl. Acad. Sci. USA. 83:1986;7104-7108.
50. Yue T.L., Feuerstein G.Z. Platelet-activating factor: a putative neuromodulator and mediator in the pathophysiology of brain injury. Crit. Rev. Neurobiol. 8:1994;11-24.