The U(L)16 gene product of herpes simlex virus 1 is a virion protein that colocalizes with intranuclear capsid proteins

Virology

Volumn 226, Issue 2, 1996, Pages 236-242

  Nalwanga, Dorothy ^a   Rempel, Stephanie ^a   Roizman, Bernard ^b   Baines, Joel D ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; HYBRID PROTEIN; VIRUS PROTEIN;

ARTICLE; DNA SYNTHESIS; HERPES SIMPLEX VIRUS 1; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL LINE; CERCOPITHECUS; CONFOCAL MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; VERO CELL; VIRION; VIRUS CAPSID;

ANIMALS; CAPSID; CELL LINE; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 1, HUMAN; HUMANS; MICROSCOPY, CONFOCAL; RECOMBINANT FUSION PROTEINS; VERO CELLS; VIRAL PROTEINS; VIRION;

EID: 0030589196     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0651     Document Type: Article

References (18)

1. L16 are dispensable for the growth of herpes simplex virus 1 in cell culture. J. Virol. 65, 938-944.
2. L15, a highly conserved herpes simplex virus 1 gene, effectively replaces the two exons of the wild type virus. J. Virol. 66, 5621-5626.
3. L10 gene of herpes simplex virus 1 encodes a novel glycoprotein, gM, which is present in the virion and in the plasma membrane of infected cells. J. Virol. 67, 1441-1452.
4. L21 gene of herpes simplex virus 1 is dispensable for replication in cell culture. J. Virol. 68, 2929-2936.
5. Costa, R. H., Draper, K. G., Kelly, T. J., and Wagner, E. K. (1985). An unusual spliced herpes simplex virus type 1 transcript with sequence homology to Epstein-Barr virus DNA. J. Virol. 54, 317-328.
6. Ejercito, P. M., Kieff, E. D., and Roizman, B. (1968). Characterization of herpes simplex virus strains differing in their effects on social behavior of infected cells. J. Gen. Virol. 2, 357-364.
7. Gibson, W., and Roizman, B. (1972). Proteins specified by herpes simplex virus VIII. Characterization and composition of multiple capsid forms of subtypes 1 and 2. J. Virol. 10, 1044-1052.
8. Johnson, D. C., Frame, M. C., Ligas, M. W., Cross, A. M., and Stow, N. D. (1988). Herpes simplex virus immunoglobulin G Fc receptor activity depends on a complex of two viral glycoproteins, gE and gl. J. Virol. 62, 1347-1354.
9. Johnson, G. D., and Araujo, G. M., de C. N. (1981). A simple method of reducing the fading of immunofluorescence during microscopy. J. Immunol. Methods 43, 349-350.
10. McGeoch, D. J., Dalrymple, M. A., Davison, A. J., Dolan, A., Frame, M. C., McNab, D., Perry, L. J., Scott, J. E., and Taylor, P. (1988). The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J. Gen. Virol. 69, 1531-1574.
11. Newcomb, W. W., and Brown, J. C. (1991). Structure of the herpes simplex virus capsid: Effects of extraction with guanidine hydrochloride and partial reconstitution of extracted capsids. J. Virol. 65, 613-620.
12. Post, L. E., Mackem, S., and Roizman, B. (1981). Regulation of α genes of herpes simplex virus: expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters. Cell 25, 227-232.
13. Quinlan, M. P., Chen, L. B., and Knipe, D. M. (1984). The intranuclear location of a herpes simplex virus DNA-binding protein is determined by the status of viral DNA replication. Cell 36, 857-868.
14. Spear, P. G., and Roizman, B. (1972). Proteins specified by herpes simplex virus V. Purification and structural proteins of the herpesvirion. J. Virol. 9, 143-159.
15. Walboomers, J. M., and Ter Schagget, J. (1976). A new method for the isolation of herpes simplex virus type 2 DNA. Virology 74, 256-258.
16. L43 gene and encodes a protein which colocalizes in nuclear structures with capsid proteins. J. Virol. 70, 2684-2690.
17. Ward, P. L., Ogle1W. O., and Roizman, B. (1996b). Assemblons: Nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1. J. Virol. 70, 4623-4631.
18. Wing, B. A., Lee, G. C. Y., and Huang, E. S. (1996). The human cytomegalovirus UL94 open reading frame encodes a conserved herpesvirus capsid/tegument-associated virion protein that is expressed with true late kinetics. J. Virol. 70, 3339-3345.