Improved ex vivo/in vitro lymph node cell proliferation assay in guinea pigs for a screening test of contact hypersensitivity of chemical compounds

Toxicology

Volumn 114, Issue 1, 1996, Pages 47-55

  Kashima, Ryuichi ^a   Oyake, Yumiko ^a   Okada, Joshin ^a   Ikeda, Yuzo ^a  

^a KAO CORPORATION   (Japan)

Author keywords

24 h occlusive patch sensitization (24 CP); Contact hypersensitivity; Guinea pig; Lymph node cell proliferation assay; Screening

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; BENZOCAINE; CINNAMALDEHYDE; CONTACT ALLERGEN; DODECYL SULFATE SODIUM; FLAVORING AGENT; FORMALDEHYDE; NEOMYCIN; NICKEL SULFATE; PHENYLENEDIAMINE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTACT ALLERGY; CONTROLLED STUDY; FEMALE; GUINEA PIG; HISTOCHEMISTRY; INTRADERMAL DRUG ADMINISTRATION; LYMPH NODE CELL; NONHUMAN; PRIORITY JOURNAL; SCREENING TEST; SENSITIZATION; TECHNIQUE;

ANIMALIA; CAVIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0030589079     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(96)89846-5     Document Type: Article

References (15)

1. Basketter, D.A., Scholes, E.W. and Kimber, I. (1994) The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test. Food Chem. Toxicol. 32, 543-547.
2. Edwards, D.A., Soranno, T.M., Amoruso, M.A., House, R.V., Tummey, A.C., Trimmer, G.W., Thomas, P.T. and Ribeiro, P.L. (1994) Screening petrochemicals for contact hypersensitivity potential: a comparison of the murine local lymph node assay with guinea pig and human test data. Fundam. Appl. Toxicol. 23, 179-187.
3. EEC (1992) Annex to commission directive 92/69/EEC of 31 July 1992 adapting to technical progress for the seventeenth time council directive 67/548/EEC on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Part B: Methods for the determination of toxicity. B6. Skin sensitization. Official Journal of the European Communities L383A, 35, 131-136.
4. Gratzner, H.G., Leif, R.C., Ingram, D.J. and Castro, A. (1975) The use of antibody specific for bromodeoxyuridine for the immunofluorescent determination of DNA replication in single cells and chromosomes. Exp. Cell Res. 95, 88-94.
5. Japanese Ministry of Health and Welfare (1990) Skin sensitizing studies. In: Guidelines for Toxicity Studies of Drugs. Editorial supervision by New Drug Division, Pharmaceutical Affairs Bureau, Japanese Ministry of Health and Welfare, Yakuji Nippo, Tokyo, pp. 75-80.
6. Kashima, R., Oyake, Y., Okada, J. and Ikeda, Y. (1993) Studies of new short-period method for delayed contact hypersensitivity assay in the guinea pig. I. Development and comparison with other methods. Contact Dermat. 28, 235-242.
7. Kashima, R., Okada, J. and Ikeda, Y. (1994) Lymph node cell proliferation assay in guinea pigs for the assessment of sensitizing potentials of chemical compounds. Food Chem. Toxicol. 32, 831-836.
8. Kimber, I. and Basketter, D.A. (1992). The murine local lymph node assay: a commentary on collaborative studies and new directions. Food Chem. Toxicol. 30, 165-169.
9. Kimber, I., Mitchell, J.A. and Griffin, A.C. (1986) Development of a murine local lymph node assay for the determination of sensitizing potential. Food Chem. Toxicol. 24, 585-586
10. Kimber, I., Dearman, R.J., Scholes, E.W. and Basketter, D.A. (1994). The local lymph node assay: developments and applications. Toxicology 93, 13-31.
11. OECD (1992) Skin sensitization. OECD guidelines for testing of chemicals, No. 406, Skin sensitization, OECD, Paris.
12. Oort, J. and Turk, J.L. (1965) A histological and autoradiographic study of lymph nodes during the development of contact sensitivity in the guinea-pig. Br. J. Exp. Pathol. 46, 147-154.
13. Polak, L. (1980) Immunological aspects of contact sensitivity. An experimental study. In: P. Dukor, P. Kallos, Z. Trnka, B.H. Waksman and A.L. de Weck (Eds), Monographs in Allergy, Vol. 15, Kager, Basel, p. 2.
14. Scholes, E.W., Basketter, D.A., Sarll, A.E., Kimber, I., Evans, C.D., Miller, K., Robbins, M.C., Harrison, P.T.C. and Waite, S.J. (1992) The local lymph node assay: results of a final inter-laboratory validation under field conditions. J. Appl. Toxicol. 12, 217-222.
15. Tsuchiya, S., Kondo, M., Okamoto, K. and Takase, Y. (1985) The cumulative contact enhancement test. In: K.E. Andersen and H.I. Maibach, (Eds), Current Problems in Dermatology, Vol. 14, Karger, Basel, pp. 208-219.