Opposing actions of cholinergic agonist and trinitroglycerin on net Vascular resistance in perfused rat heart

International Journal of Cardiology

Volumn 57, Issue 1, 1996, Pages 9-19

  Lockwood, Thomas D ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Acetyl methacholine; Acetylcholine; Coronary artery; Nitrovasodilator; Vascular resistance

Indexed keywords

ACETYLCHOLINE; ATROPINE; CHOLINERGIC RECEPTOR STIMULATING AGENT; GLYCERYL TRINITRATE; ISOPRENALINE; METHACHOLINE; PHENYLEPHRINE; PRAZOSIN; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICHOLINERGIC EFFECT; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR RESISTANCE;

ACETYLCHOLINE; ANIMALS; CHOLINERGIC AGONISTS; FEMALE; HEART; METHACHOLINE CHLORIDE; MYOCARDIAL CONTRACTION; NITROGLYCERIN; PREGNANCY; RATS; VASCULAR RESISTANCE; VASODILATOR AGENTS;

EID: 0030589068     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5273(96)02775-1     Document Type: Article

References (35)

1. [1] Kalsner S. Cholinergic constriction in the general circulation and its role in coronary artery spasm. Circulation Res 1989; 65: 237-257.
2. [2] Angus JA, Cock TM, McPherson GA, Broughton A. The acetylcholine paradox: A constrictor of human small coronary arteries even in presence of endothelium. Clin Exp Pharmacol Physiol 1991; 18: 33-36.
3. [3] Bognar IT, Beinhauer B, Kann P, Fuder H. Different muscarinic receptors mediate autoinhibition of acetylcholine release and vagally-induced vasoconstriction in the rat isolated perfused heart. Naunyn-Schmied Arch Pharmacol 1989; 341: 279-287.
4. [4] Endo M, Hirosawa K, Kaneko N, Hase K, Yuoue Y, Konno S. Coronary arteriogram and left ventriculogram during angina attack induced by methacholine. N Engl J Med 1976; 294: 252.
5. [5] Kugiyama K, Yasue H, Horio Y, Morikami Y, Fujii H, Kimura T. Possible role of parasympathetic nervous system in the pathogenesis of exercise-induced coronary artery spasm. Am Heart J, 1986; 605: 100-110.
6. [6] Nitenberg A, Anthony I, Foult J. Acetylcholine-induced coronary vasoconstriction in young heavy smokers with normal coronary arteriographic findings. Am J Med 1993; 95: 71-77.
7. [7] Okumura K, Yasue H, Matsuyama K, Goto K, Miyogi H, Ogawa H, Matsuyama K. Sensitivity and specificity of intracoronary injection of acetylcholine for the induction of coronary artery spasm. J Am Coll Cardiol 1988; 12: 883-888.
8. [8] Okumura K, Yasue H, Matsuyama K, Matsuyama K, Morikami Y, Ogawa H, Obata K. Effect of H1 receptor stimulation on coronary artery diameter in patients with variant angina: comparison with effect of acetylcholine. J Am Coll Cardiol 1991; 17: 338-345.
9. [9] Saitoh Y, Sasaki F, Ishizaki T, Miyabo S, Kanamori K, Mifure J. Bronchial hyperresponsiveness to acetylcholine in patients with vasospastic angina pectoris. Chest 1994; 105: 364-367.
10. [10] Van Charldorp KJ, De Jong A, Davidesko D, Rinner I, Dodds HN, Van Zwieten PA. Coronary constriction induced by vagal stimulation in the isolated rat heart. Eur J Pharmacol 1987; 136: 135-136.
11. [11] Yamanishi K, Fujita M, Miwa K, Igawa A. Effect of intracoronary injection of acetylcholine on coronary collateral circulation. Catheter Cardiovasc Diagnosis 1993; 28: 114-118.
12. [12] Yang BC, Nichols WW, Mehta JL. Cardiac effects of acetylcholine in rat hearts: role of endothelium-derived relaxing factor and prostaglandins. Am J Physiol 1993; 264: H1388-H1393.
13. [13] Yasue H, Touyama M, Shimamoto M, Kato H, Tanaka S, Akiyama F. Role of autonomic nervous system in the pathogenesis of Prinzmetal's variant form of angina. Circulation 1974; 50: 534.
14. [14] Yasue H, Horio Y, Nakamura N, Fujii H, Imoto N, Sonada R, Kugiyama K, Obata K, Morikami Y, Kimura T. Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. Circulation 1986; 74: 955.
15. [15] Brunner F, Kuhberger E, Groschener K, Poch G, Kukovetz WR. Characterization of muscarinic receptors mediating endothelium-dependent relaxation of bovine coronary artery. Eur J Pharmacol 1991; 200: 25-33.
16. [16] Cannon RO Acetylcholine and coronary artery spasm: Important insight or squeeze play. J Am Coll Cardiol 1988; 889-891.
17. [17] Cowan CL, McKenzie JE. Cholinergic regulation of resting coronary blood flow in domestic swine. Am J Physiol 1990; 259: H109-H115.
18. [18] Egashira K, Ihon T, Hirooka Y, Kai H, Sugimachi M, Suzuki S, Kuga T, Urabe Y, Takeshila A. Effects of age on endothelium dependent vasodilation of resistance coronary artery by acetylcholine in human. Circulation 1993; 88: 77-81.
19. [19] El-Tamini H, Mansour M, Wargovich TJ, Hill JA, Keronsky RA, Conti CR, Pepine CJ. Constrictor and dilator responses to intracoronary acetylcholine in adjacent segments of the same coronary artery in patients with coronary disease: Endothelial function revisited. Circulation 1994; 89: 45-51.
20. [20] Hodgson J, Marshall JJ. Direct vasoconstriction and endothelium-dependent vasodilation. Mechanisms of acetylcholine effects on coronary flow and arterial diameter in patients with non-stenotic coronary arteries. Circulation 1989; 79: 1043-1051.
21. [21] Ito BR, Feigl EO. Carotid chemoreceptor reflex parasympathetic coronary vasodilation in the dog. Am J Physiol 1985; 249: H1167-H1176.
22. [22] Kawamura A, Fujiwara H, Onoderea T, Wu DJ, Matsuda M, Ishida M, Takemura G, Fijuwara Y, Kawai C. Response of large and small coronary arteries of pigs to intercoronary injection of acetylcholine: angiographic and histologic analysis. Int J Cardiol 1989; 25: 289-302.
23. [23] Knight DR, Shen Y, Young MA, Vatner SF. Acetylcholine-induced coronary vasoconstriction and vasodilation in tranquilized baboons. Circ Res 1991; 69: 706-713.
24. [24] Miwa K, Fujita M, Ejiri M, Sasayama S. Biphasic changes (initial increase and late decrease) in coronary sinus venous oxygen saturation during anginal attacks induced by intracoronary acetylcholine in patients with variant angina. Cardiol 1992; 81: 221-232.
25. [25] Nakayama K, Osol G, Halpern W. Reactivity of isolated porcine coronary arteries to cholinergic and adrenergic drugs and transmural pressure changes. Circ Res 1988; 62: 741-748.
26. [26] Penny WF, Rockman H, Long J, Bhargara V, Carrigan K, Ibraham A, Shabetai R, Ross J, Peterson KL. Heterogeneity of vasomotor response to acetylcholine along the human coronary artery. J Am Coll Cardiol 1995; 25: 1046-1055.
27. [27] Vrint CJ, Bult H, Hitler E, Herman AG, Snoeck JP. Impaired endothelium dependent cholinergic coronary vasodilation in patients with angina and normal coronary arteriograms. J Am Coll Cardiol 1992; 19: 21-31.
28. [28] Van Winkle DM, Feigl EO. Acetylcholine causes coronary vasodilation in dogs and baboons. Circ Res 1989; 65: 158-159.
29. [29] Hoffman JI, Spaan JA. Pressure-flow relations in coronary circulation. Physiol Rev 1990; 70: 331-373.
30. [30] Gross SS, Wolin MS. Nitric Oxide: Pathophysiological Mechanisms. Annu Rev Physiol 1995; 57: 737-769.
31. [31] Inagami T, Naruse M, Hoover R. Endothelium as an endocrine organ. Annu Rev Physiol 1995; 47: 171-189.
32. [32] Umans JG, Levi R. Nitric Oxide in the regulation of blood flow and arterial pressure. Annu Rev Physiol 1995; 57: 771-790.
33. [33] Thorne, DT, Lockwood T. Four proteolytic processes of myocardium, one insensitive to thiol-reactive agents and thiol protease inhibitor. Am J Physiol 1993; 265: E10-E19.
34. [34] Kawashima K, Watanabe N, Oohata H, Fujimoto K, Suzuki T, Ishizaki Y, Morita I, Murota S. Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells. Neurosci Lett 1990; 119: 156-158.
35. [35] Milner P, Kirkpatrick KA, Ralevic V, Toothhill V, Pearson J, Burnstock G. Endothelial cells cultured from human umbilical vein release ATP, substance P and acetylcholine in response to increased flow. Proc R Soc London Biol Sci 1990; 241: 245-248.