Simultaneous determination of GTS-21 and its metabolite in rat plasma by high-performance liquid chromatography using solid-phase extraction

Journal of Chromatography B: Biomedical Applications

Volumn 686, Issue 2, 1996, Pages 229-234

  Azuma, Ryotaro ^a   Minami, Yoshinori ^a   Satoh, Toshiyuki ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

3 (2,4 Dimethyloxygenzylidene)arnabaseine; Nicotinic acetylcholine receptor agonist

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; ANABASINE DERIVATIVE; DRUG METABOLITE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; SPECTROPHOTOMETRY; TECHNIQUE;

ANIMALS; BENZYLIDENE COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; NICOTINIC AGONISTS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0030589017     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(96)00233-2     Document Type: Article

References (4)

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2. [2] E.J. Martin, K.S. Panicker, M.A. King, M. Deyrup, B.E. Hunter and E.M. Meyer, Drug Dev. Res., 31 (1994) 135.
3. [3] C.M. de Fiebre, E.M. Meyer, J.C. Henry, S.I. Muraskin, W.R. Kem and R.L. Parke, Mol. Pharmacol., 47 (1995) 164.
4. [4] K.C. Van Horne, Sorbent Extraction Technology, Analytichem International, Harbor City, 1985, p. 24.