메뉴 건너뛰기




Volumn 225, Issue 2, 1996, Pages 328-338

Enhancement of hepatitis C virus NS3 proteinase activity by association with NS4A-Specific synthetic peptides: Identification of sequence and critical residues of NS4A for the cofactor activity

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; SYNTHETIC PEPTIDE;

EID: 0030589011     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0607     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 0027285404 scopus 로고
    • Dengue 2 virus NS2B and NS3 form a stable complex that can cleave NS3 within the helicase domain
    • Arias, C. F., Preugschat, F., and Strauss, J. H. (1993). Dengue 2 virus NS2B and NS3 form a stable complex that can cleave NS3 within the helicase domain. Virology 193, 888-899.
    • (1993) Virology , vol.193 , pp. 888-899
    • Arias, C.F.1    Preugschat, F.2    Strauss, J.H.3
  • 2
    • 0028241489 scopus 로고
    • Kinetic and structural analyses of hepatitis C virus polyprotein processing
    • Bartenschlager, R., Ahlborn-Laake, I., Mous, J., and Jacobsen, H. (1994). Kinetic and structural analyses of hepatitis C virus polyprotein processing. J. Virol. 68, 5045-5055.
    • (1994) J. Virol. , vol.68 , pp. 5045-5055
    • Bartenschlager, R.1    Ahlborn-Laake, I.2    Mous, J.3    Jacobsen, H.4
  • 3
    • 0028820118 scopus 로고
    • Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation
    • Bartenschlager, R., Lohmann, V., Wilkinson, T., and Koch, J. O. (1995). Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation. J. Virol. 69, 7519-7528.
    • (1995) J. Virol. , vol.69 , pp. 7519-7528
    • Bartenschlager, R.1    Lohmann, V.2    Wilkinson, T.3    Koch, J.O.4
  • 4
    • 0026039916 scopus 로고
    • Processing of the yellow fever nonstructural polyprotein: A catalytically active NS3 proteinase domain and NS2B are required for cleavage at dibasic sites
    • Chambers, T. J., Grakoui, A., and Rice, C. M. (1991). Processing of the yellow fever nonstructural polyprotein: A catalytically active NS3 proteinase domain and NS2B are required for cleavage at dibasic sites. J. Virol. 65, 6042-6050.
    • (1991) J. Virol. , vol.65 , pp. 6042-6050
    • Chambers, T.J.1    Grakoui, A.2    Rice, C.M.3
  • 5
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo, Q-L., Kuo, G., Weiner, A., Overby, L. R., Bradley, D. W., and Houghton, M. (1989). Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244, 359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.-L.1    Kuo, G.2    Weiner, A.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 7
    • 0027308676 scopus 로고
    • Cell-free expression vector: Use of insect virus translational initiation signal for in vitro gene expression
    • DasMahapatra, B. (1993). Cell-free expression vector: Use of insect virus translational initiation signal for in vitro gene expression. Methods Enzymol. 217, 143-151.
    • (1993) Methods Enzymol. , vol.217 , pp. 143-151
    • DasMahapatra, B.1
  • 8
    • 0025352629 scopus 로고
    • Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase: Evidence for temporal regulation of polyprotein processing in vivo
    • de Groot, R. J., Hardy, W. R., Shirako, Y., and Strauss, J. H. (1990). Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase: Evidence for temporal regulation of polyprotein processing in vivo. EMBO J. 9, 2631-2638.
    • (1990) EMBO J. , vol.9 , pp. 2631-2638
    • De Groot, R.J.1    Hardy, W.R.2    Shirako, Y.3    Strauss, J.H.4
  • 9
    • 0028290579 scopus 로고
    • Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins
    • Failla, C., Tomei, L., and De Francesco, R. (1994). Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins. J. Virol. 68, 3753-3760.
    • (1994) J. Virol. , vol.68 , pp. 3753-3760
    • Failla, C.1    Tomei, L.2    De Francesco, R.3
  • 10
    • 0028851296 scopus 로고
    • An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A
    • Failla, C., Tomei, L., and De Francesco, R. (1995). An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A. J. Virol. 69, 1769-1777.
    • (1995) J. Virol. , vol.69 , pp. 1769-1777
    • Failla, C.1    Tomei, L.2    De Francesco, R.3
  • 11
    • 0025864149 scopus 로고
    • Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins
    • Falgout, B., Pethel, M., Zhang, Y-M., and Lai, C-J. (1991). Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins. J. Virol. 65, 2467-2475.
    • (1991) J. Virol. , vol.65 , pp. 2467-2475
    • Falgout, B.1    Pethel, M.2    Zhang, Y.-M.3    Lai, C.-J.4
  • 12
    • 0027414062 scopus 로고
    • Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
    • Grakoui, A., McCourt, D. W., Wychowski, C., Feinstone, S. M., and Rice, C. M. (1993b). Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites. J. Virol. 67, 2832-2843.
    • (1993) J. Virol. , vol.67 , pp. 2832-2843
    • Grakoui, A.1    McCourt, D.W.2    Wychowski, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 14
    • 0027476809 scopus 로고
    • Expression and identification of hepatitis C virus polyprotein cleavage products
    • Grakoui, A., Wychowski, C., Lin, C., Feinstone, S. M., and Rice, C. M. (1993a). Expression and identification of hepatitis C virus polyprotein cleavage products. J. Virol. 67, 1385-1395.
    • (1993) J. Virol. , vol.67 , pp. 1385-1395
    • Grakoui, A.1    Wychowski, C.2    Lin, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 16
    • 0025991559 scopus 로고
    • Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
    • Hijikata, M., Kato, N., Ootsuyama, Y., Nakagawa, M., and Shimotohno, K. (1991). Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl. Acad. Sci. USA 88, 5547-5551.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5547-5551
    • Hijikata, M.1    Kato, N.2    Ootsuyama, Y.3    Nakagawa, M.4    Shimotohno, K.5
  • 17
    • 0027163740 scopus 로고
    • Two distinct proteinase activities required for the processing of a putative non-structural precursor protein of hepatitis C virus
    • Hijikata, M., Mizushima, H., Akagi, T., Mori, S., Kakiuchi, N., Kato, N., Tanaka, T., Kimura, K., and Shimotohno, K. (1993). Two distinct proteinase activities required for the processing of a putative non-structural precursor protein of hepatitis C virus. J. Virol. 67, 4665-4675.
    • (1993) J. Virol. , vol.67 , pp. 4665-4675
    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7    Kimura, K.8    Shimotohno, K.9
  • 18
    • 0023870815 scopus 로고
    • Characterization of ribosomal frameshifting in HIV-1 gag-pol expression
    • Jacks, T., Power, M. D., Masiarz, F. R., Luciw, P. A., Barr, P. J., and Varmus, H. E. (1988). Characterization of ribosomal frameshifting in HIV-1 gag-pol expression. Nature 331, 280-283.
    • (1988) Nature , vol.331 , pp. 280-283
    • Jacks, T.1    Power, M.D.2    Masiarz, F.R.3    Luciw, P.A.4    Barr, P.J.5    Varmus, H.E.6
  • 19
    • 0023952330 scopus 로고
    • Poliovirus protein 3CD is the active protease for processing of the precursor P1 in vitro
    • Jore, J., Geus, B. D., Jackson, R. J., Pouwels, P. H., and Enger-Valk, B. E. (1988). Poliovirus protein 3CD is the active protease for processing of the precursor P1 in vitro. J. Gen. Virol. 69, 1627-1636.
    • (1988) J. Gen. Virol. , vol.69 , pp. 1627-1636
    • Jore, J.1    Geus, B.D.2    Jackson, R.J.3    Pouwels, P.H.4    Enger-Valk, B.E.5
  • 20
    • 0026322839 scopus 로고
    • Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity
    • Krausslich, H-G. (1991). Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity. Proc. Natl. Acad. Sci. USA 88, 3213-3217.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3213-3217
    • Krausslich, H.-G.1
  • 22
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 23
    • 0029094449 scopus 로고
    • The hepatitis C virus NS3 serine proteinase and NS4A cofactor: Establishment of a cell-free trans-processing assay
    • Lin, C., and Rice, C. M. (1995). The hepatitis C virus NS3 serine proteinase and NS4A cofactor: Establishment of a cell-free trans-processing assay. Proc. Natl. Acad. Sci. USA 92, 7622-7626.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7622-7626
    • Lin, C.1    Rice, C.M.2
  • 24
    • 0028290389 scopus 로고
    • Processing of the hepatitis C virus E2-NS2 region: Identification of p7 and two distinct E2-specific products with different C termini
    • Lin, C., Lindenbach, B. D., Pragai, B. M., McCourt, D. W., and Rice, C. M. (1994). Processing of the hepatitis C virus E2-NS2 region: Identification of p7 and two distinct E2-specific products with different C termini. J. Virol. 68, 5063-5073.
    • (1994) J. Virol. , vol.68 , pp. 5063-5073
    • Lin, C.1    Lindenbach, B.D.2    Pragai, B.M.3    McCourt, D.W.4    Rice, C.M.5
  • 25
    • 0028089739 scopus 로고
    • Hepatitis C virus NS3 serine proteinase: Trans-cleavage requirements and processing kinetics
    • Lin, C., Pragai, B. M., Graouki, A., Xu, J., and Rice, C. M. (1994). Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J. Virol. 68, 8147-8157.
    • (1994) J. Virol. , vol.68 , pp. 8147-8157
    • Lin, C.1    Pragai, B.M.2    Graouki, A.3    Xu, J.4    Rice, C.M.5
  • 26
    • 0029074519 scopus 로고
    • A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro
    • Lin, C., Thomson, J. A., and Rice, C. M. (1995). A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro. J. Virol. 69, 4373-4380.
    • (1995) J. Virol. , vol.69 , pp. 4373-4380
    • Lin, C.1    Thomson, J.A.2    Rice, C.M.3
  • 27
    • 0027390796 scopus 로고
    • Viral DNA and a viral peptide can act as cofactors of adenovirus virion proteinase activity
    • Mangel, W. F., McGrath, W. J., Toledo, D. I., and Anderson, C. W. (1993). Viral DNA and a viral peptide can act as cofactors of adenovirus virion proteinase activity. Nature 361, 274-275.
    • (1993) Nature , vol.361 , pp. 274-275
    • Mangel, W.F.1    McGrath, W.J.2    Toledo, D.I.3    Anderson, C.W.4
  • 28
    • 0025249362 scopus 로고
    • Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups
    • Miller, R. H., and Purcell, R. H. (1990). Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proc. Natl. Acad. Sci. USA 87, 2057-2061.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2057-2061
    • Miller, R.H.1    Purcell, R.H.2
  • 31
    • 0029059334 scopus 로고
    • Hepatitis C virus-encoded NS2-3 protease: Cleavage-site mutagenesis and requirements for bimolecular cleavage
    • Reed, K. E., Grakoui, A., and Rice, C. M. (1995). Hepatitis C virus-encoded NS2-3 protease: Cleavage-site mutagenesis and requirements for bimolecular cleavage. J. Virol. 69, 4127-4136.
    • (1995) J. Virol. , vol.69 , pp. 4127-4136
    • Reed, K.E.1    Grakoui, A.2    Rice, C.M.3
  • 32
    • 0001424128 scopus 로고
    • Flaviviridae: The viruses and their replication
    • (B. N. Fields, D. M. Knipe, and P. M. Howley, Eds.). Raven Press, New York
    • Rice, C. M. (1995). Flaviviridae: The viruses and their replication. In "Fields Virology" (B. N. Fields, D. M. Knipe, and P. M. Howley, Eds.). Raven Press, New York.
    • (1995) Fields Virology
    • Rice, C.M.1
  • 34
    • 0029655995 scopus 로고    scopus 로고
    • Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease
    • Shimuzu, Y., Yamaji, K., Masuho, Y., Yokota, T., Inoue, H., Sudo, K., Satoh, S., and Shimotohno, K. (1996). Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease. J. Virol. 70, 127-132.
    • (1996) J. Virol. , vol.70 , pp. 127-132
    • Shimuzu, Y.1    Yamaji, K.2    Masuho, Y.3    Yokota, T.4    Inoue, H.5    Sudo, K.6    Satoh, S.7    Shimotohno, K.8
  • 36
    • 0029981534 scopus 로고    scopus 로고
    • In vitro activity of hepatitis C virus protease NS3 purified from recombinant baculovirus-infected Sf9 cells
    • Steinkuhler, C., Tomei, L., and De Francesco, R. (1996). In vitro activity of hepatitis C virus protease NS3 purified from recombinant baculovirus-infected Sf9 cells. J. biol. chem. 271, 6367-6373
    • (1996) J. Biol. Chem. , vol.271 , pp. 6367-6373
    • Steinkuhler, C.1    Tomei, L.2    De Francesco, R.3
  • 38
    • 0028831056 scopus 로고
    • Hepatitis C virus-encoded nonstructural protein NS4Ahas versatile functions in viral protein processing
    • Tanji, Y., Hijikata, M., Satoh, S., Kaneko, T., and Shimotohno, K. (1995). Hepatitis C virus-encoded nonstructural protein NS4Ahas versatile functions in viral protein processing. J. Virol. 69, 1575-1581.
    • (1995) J. Virol. , vol.69 , pp. 1575-1581
    • Tanji, Y.1    Hijikata, M.2    Satoh, S.3    Kaneko, T.4    Shimotohno, K.5
  • 39
    • 0028978937 scopus 로고
    • Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A
    • Tanji, Y., Takashi, K., Satoh, S., and Shimotohno, K. (1995). Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J. Virol. 69, 3980-3986.
    • (1995) J. Virol. , vol.69 , pp. 3980-3986
    • Tanji, Y.1    Takashi, K.2    Satoh, S.3    Shimotohno, K.4
  • 40
    • 0027176287 scopus 로고
    • NS3 is a serine protease required for hepatitis C virus polyprotein
    • Tomei, L., Failla, C., Santolini, E., De Francesco, R., and La Monica, N. (1993). NS3 is a serine protease required for hepatitis C virus polyprotein. J. Virol. 67, 4017-4026.
    • (1993) J. Virol. , vol.67 , pp. 4017-4026
    • Tomei, L.1    Failla, C.2    Santolini, E.3    De Francesco, R.4    La Monica, N.5
  • 41
    • 0027509951 scopus 로고
    • The adenovirus protease is activated by a virus-coded disulphide-linked peptide
    • Webster, A., Hay, R. T., and Kemp, G. (1993). The adenovirus protease is activated by a virus-coded disulphide-linked peptide. Cell 72, 97-104.
    • (1993) Cell , vol.72 , pp. 97-104
    • Webster, A.1    Hay, R.T.2    Kemp, G.3
  • 42
    • 0024077061 scopus 로고
    • Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursor
    • Ypma-Wong, M. F., Dewalt, P. G., Johnson, V. H., Lamb, J. G., and Semler, B. L. (1988). Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursor. Virology 166, 265-270.
    • (1988) Virology , vol.166 , pp. 265-270
    • Ypma-Wong, M.F.1    Dewalt, P.G.2    Johnson, V.H.3    Lamb, J.G.4    Semler, B.L.5
  • 43
    • 0021076777 scopus 로고
    • A single gene and a pseudogene for the cellular tumour antigen p53
    • Zakut-Houri, R., Oren, M., Bienz, B., Lavie, V., Hazum, S., and Givol, D. (1983). A single gene and a pseudogene for the cellular tumour antigen p53. Nature 306, 594-597.
    • (1983) Nature , vol.306 , pp. 594-597
    • Zakut-Houri, R.1    Oren, M.2    Bienz, B.3    Lavie, V.4    Hazum, S.5    Givol, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.