Amino acid residue 104 in an α-class glutathione S-transferase is essential for the high selectivity and specificity of the enzyme for 4- hydroxynonenal

Archives of Biochemistry and Biophysics

Volumn 335, Issue 2, 1996, Pages 305-310

  Nanduri, Bindu ^a   Hayden, Janet B ^a   Awasthi, Yogesh C ^b   Zimniak, Piotr ^a,c  

^a CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

4 hydroxynonenal; glutathione S transferase; site directed mutagenesis

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 4 HYDROXYNONENAL; GLUTATHIONE TRANSFERASE;

AMINO ACID METABOLISM; ARTICLE; CRYSTAL STRUCTURE; CYTOTOXICITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; LIPID PEROXIDATION; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; X RAY ANALYSIS;

MURINAE;

EID: 0030588937     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0511     Document Type: Article

References (24)

1. 1. Sinning, I., Kleywegt, G. J., Cowan, S. W., Reinemer, P., Dirr, H. W., Huber, R., Gilliland, G. L., Armstrong, R. N., Ji, X., Board, P. G., Olin, B., Mannervik, B., and Jones, T. A. (1993) J. Mol. Biol. 232, 192-212.
2. 2. Van Ness, K. P., Buetler, T. M., and Eaton, D. L. (1994) Cancer Res. 54, 4573-4575.
3. 3. Zhang, P., Liu, S., Shan, S. O., Ji, X., Gilliland, G. L., and Armstrong, R. N. (1992) Biochemistry 31, 10185-10193.
4. 4. Bjornestedt, R., Widersten, M., Board, P. G., and Mannervik, B. (1992) Biochem. J. 282, 505-510.
5. 5. Zimniak, P., Eckles, M. A., Saxena, M., and Awasthi, Y. C. (1992) FEBS Lett. 313, 173-176.
6. 6. Zimniak, P., Singhal, S. S., Srivastava, S. K., Awasthi, S., Sharma, R., Hayden, J. B., and Awasthi, Y. C. (1994) J. Biol. Chem. 269, 992-1000.
7. 7. Hoier, H., Arkema, A., Kalk, K., Zimniak, P., and Dijkstra, B. W. (1994) in Proceedings, American Crystallographic Association meeting, June 25-July 1, Atlanta, GA.
8. 8. Awasthi, Y. C., Zimniak, P., Awasthi, S., Singhal, S. S., Srivastava, S. K., Piper, J. T., Chaubey, M., Petersen, D. R., He, N.-g., Sharma, R., Singh, S. V., Khan, M. F., Ansari, G. A. S., and Boor, P. J. (1996) in Proceedings of the International ISSX Workshop on glutathione S-transferases (Vermeulen, N. P. E., Ed.), pp. 111-124, Taylor & Francis, London.
9. 9. Awasthi, Y. C., Zimniak, P., Singhal, S. S., and Awasthi, S. (1995) Biochem. Arch. 11, 47-54.
10. 10. Simons, P. C., and Vander Jagt, D. L. (1977) Anal. Biochem. 82, 334-341.
11. 11. Ahmad, H., Singh, S. V., Medh, R. D., Ansari, G. A. S., Kurosky, A., and Awasthi, Y. C. (1988) Arch. Biochem. Biophys. 266, 416-426.
12. 12. Habig, W. H., Pabst, M. J., and Jakoby, W. B. (1974) J. Biol. Chem. 249, 7130-7139.
13. 13. Alin, P., Danielson, U. H., and Mannervik, B. (1985) FEBS Lett. 179, 267-270.
14. 14. Cornish-Bowden, A., and Eisenthal, R. (1978) Biochim. Biophys. Acta 523, 268-272.
15. 15. Rawn, J. D. (1989) in Biochemistry, pp. 174-176, Neil Patterson Publ., Carolina Biological Supply Co., Burlington, NC.
16. 16. Sayle, R. A., and Milner-White, E. J. (1995) Trends Biochem. Sci. 20, 374-376.
17. 17. Bjornestedt, R., Tardioli, S., and Mannervik, B. (1995) J. Biol. Chem. 270, 29705-29709.
18. 18. Bjornestedt, R., Stenberg, G., Widersten, M., Board, P. G., Sinning, I., Jones, T. A., and Mannervik, B. (1995) J. Mol. Biol. 247, 765-773.
19. 19. Esterbauer, H. (1993) Am. J. Clin. Nutr. 57, 779S-786S.
20. 20. Ahmad, S. (1995) Oxidative Stress and Antioxidant Defenses in Biology, Chapman & Hall, New York.
21. 21. Halliwell, B., and Gutteridge, J. M. C. (1989) Free Radicals in Biology and Medicine, 2nd ed., Clarendon Press, Oxford.
22. 22. Hartley, D. P., Ruth, J. A., and Petersen, D. R. (1995) Arch. Biochem. Biophys. 316, 197-205.
23. 23. Jensson, H., Guthenberg, C., Alin, P., and Mannervik, B. (1986) FEBS Lett. 203, 207-209.
24. 24. Alin, P., Jensson, H., Cederlund, E., Jornvall, H., and Mannervik, B. (1989) Biochem. J. 261, 531-539.