Effects of dietary vitamin C and E supplementation on the copper mediated oxidation of HDL and on HDL mediated cholesterol efflux

Atherosclerosis

Volumn 127, Issue 1, 1996, Pages 19-26

  Rifici, Vincent A ^a   Khachadurian, Avedis K ^a  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

antioxidant vitamins; cholesterol efflux; high density lipoprotein; oxidation

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN;

ADULT; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; COPPER METABOLISM; DIET SUPPLEMENTATION; FEMALE; HUMAN; MACROPHAGE; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADULT; ANIMALS; ASCORBIC ACID; CELLS, CULTURED; CHOLESTEROL; COPPER; CORONARY DISEASE; FEMALE; FOOD, FORTIFIED; HUMANS; LIPOPROTEINS, HDL; MACROPHAGES; MALE; MICE; MIDDLE AGED; OXIDATION-REDUCTION; PERITONEUM; REFERENCE VALUES; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TRINITROBENZENESULFONIC ACID; VITAMIN E;

EID: 0030588727     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(96)05928-X     Document Type: Article

References (40)

1. [1] Witztum JL, Steinberg D. Role of oxidized low density lipoproteins in atherogenesis. J Clin Invest 1991;88:1785.
2. [2] Carew TE, Schwenke DC, Steinberg D. Antiatherogenic effect of probucol unrelated to its hypercholesterolemic effect. Evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. Proc Natl Acad Sci USA 1987;84:772.
3. [3] Haberland ME, Fong D, Cheng L. Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits. Science 1988;241:215.
4. [4] Palinski W, Rosenfeld ME, YlaHertulla S, Gurtner GC, Sacher SS, Butler SW, Carew TE, Steinberg D, Witztum JL. Low density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci USA 1989;86:1372.
5. [5] Boyd HC, Gown AM, Wolfbauer G, Chait A. Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. Am J Pathol 1989;86:1372.
6. [6] Riemersma RA, Wood DA, MacIntyre CCA, Elton RA, Gey KF, Oliver MF. Risk of angina pectoris and plasma concentrations of vitamins A, C and E and carotene. Lancet 1991;337:1.
7. [7] Gey KF, Puska P, Jordan P, Moser UK. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. Am J Clin Nutri 1991;53:3265.
8. [8] Hodis HN, Mack WJ, LaBree L, Cashin-Hemphill L, Sevanian A, Johnson R, Azen SP. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary atherosclerosis. J Am Med Assn 1995;273:1849.
9. [9] Johnson WJ, Mahlberg FH, Rothblat GH, Phillips MC. Cholesterol transport between cells and high density lipoproteins. Biochim Biophys Acta 1991;1085:273.
10. [10] Glomset JA. The plasma lecithin cholesterol acyltransferase reaction. J Lipid Res 1968;9:155.
11. [11] Reichl D, Miller NE. Pathophysiology of reverse cholesterol transport. Insight from inherited disorders of lipoprotein metabolism. Arteriosclerosis 1989;9:785.
12. [12] Nagano Y, Hidenori A, Kita T. High density lipoprotein loses its effect to stimulate efflux of cholesterol from foam cells after oxidative modification. Proc Natl Acad Sci USA 1991;88:6457.
13. 2+ mediated oxidation. FEBS Letts 1992;314:199.
14. [14] Morel DW, Reduced cholesterol efflux to mildiy oxidized high density lipoproteins. Biochem Biophys Res Comm 1994;200:408.
15. [15] Salmon S, Maziere C, Auclair M, Theron L, Santus R, Maziere JC. Malondialdehyde modification and copper ion induced autooxidation of high density lipoproteins decrease cholesterol efflux from cultured human fibroblasts, Biochim Biophys Acta 1992;1125:230.
16. [16] Ghiselli G, Giogina L, Gelati M, Musanti R. Oxidatively modified HDLs are potent inhibitors of cholesterol biosynthesis in human skin fibroblasts. Arterioscler Thromb 1992;12:929.
17. [17] Bonnefont-Rousselot D, Motta C, Khalil AO, Sola R, LaVille AE, Delattre J, Gardes-Albert M, Physicochemical changes in human high-density lipoproteins (HDL) oxidized by gamma radiolysis-generated oxyradicals, Effect on their cholesterol effluxing capacity. Biochim Biophys Acta 1995;1255:23.
18. [18] Musanti R, Ghiselli G. Interaction of oxidized HDLs with J774. A1 macrophages causes intracellular accumulation of unesterified cholesterol. Arterioscler Thromb 1993;13:1334.
19. [19] Bowry VW, Stanley KK, Stocker R. High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors. Proc Natl Acad Sci USA 1992;89:10316.
20. [20] Jessup W, Rankin SM, DeWhally CV, Hoult JRS, Scott J, Leake DS. Alpha-tocopherol consumption during low density lipoprotein oxidation. Biochem J 1990;265:399.
21. [21] Dieber-Rotheneder M, Puhl H, Waeg G, Striegl G, Esterbauer H. Effect of oral supplementation with D alpha-tocopherol on the vitamin E content of human low density lipoproteins' resistance to oxidation. J Lipid Res 1991;32:1324.
22. [22] Jialal L, Grundy SM. Effect of dietary supplementation with alpha tocopherol on the oxidation of low density lipoprotein. J Lipid Res 1992;33:899.
23. [23] Rifici VA, Khachadurian AK. Dietary supplementation with vitamins C and E inhibits in vitro oxidation of lipoproteins. J Am Coll Nutr 1993;12:631.
24. [24] Traber MG, Kayden HJ. Preferential incorporation of α-tocopherol vs. γ-tocopherol in human lipoproteins. Am J Clin Nutr 1989;49:517.
25. [25] Suzukawa M, Ishikawa T, Yoshida H, Nakamura H. Effect of in-vivo supplementation with low-dose vitamin E on susceptibility of low-density lipoproteins to oxidative modification. J Am Coll Nutr 1995;14:46.
26. [26] Reaven PD, Witztum JL. Comparison of supplementation of RRR α-tocopherol and racemic α-tocopherol in humans. Effects on lipid levels and lipoprotein susceptibility to oxidation. Arterioscler Thromb 1993;13:601.
27. [27] Rifici VA, Khachadurian AK. Oxidation of high density lipoproteins: Characterization and effects on cholesterol efflux from J774 macrophages. Biochim Biophys Acta 1996;1299:87.
28. [28] Denson KW, Bowers EF. The determination of ascorbic acid in white blood cells. A comparison of WBC acorbic acid and phenolic acid excretion in elderly patients. Clin Sci 1961;21:157.
29. [29] Hashim SA, Schuttringer GR. Rapid determination of tocopherol in macro- and microquantities of plasma. Am J Clin Nutr 1966;19:137.
30. [30] Havel RJ, Eder HA, Bragdon JH. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 1955;34:1345.
31. [31] Hessler JR, Morel DW, Lewis LJ, Chisolm GM. Lipoprotein oxidation and lipoprotein-induced cytotoxicity. Arteriosclerosis 1983;3:215.
32. [32] Steinbrecher UP, Witztum J, Parthasarathy S, Steinberg D. Decrease in reactive amino acid groups during oxidation or endothelial cell modification of LDL. Arteriosclerosis 1987;7:135.
33. [33] Esterbauer H, Striegel G, Puhl H, Rotheneder M. Continuous monitoring of in vitro oxidation of human low density lipoproteins. Free Rad Res Commun 1989;6:67.
34. [34] Oram JF, Mendez AJ, Slotte JP, Johnson TF. High density lipoproteins apolipoproteins mediate removal of sterol from intracellular pools but not from plasma membranes of cholesterol loaded fibroblasts. Arterioscler Thromb 1991;11: 403.
35. [35] Witting PK, Bowry VW, Stocker R. Inverse kinetic isotope effect for peroxidation in human low density lipoprotein: a simple test for tocopherol mediated peroxidation of LDL lipids. FEBS Letts 1995;375:45.
36. [36] Shoukry MI, Gong EL, Nichols AV. Apolipoprotein-lipid association in oxidatively modified HDL and LDL. Biochim Biophys Acta 1994;1210:355.
37. [37] Jialal I, Grundy SM. Preservation of the endogenous antioxidants in low density lipoproteins by ascorbate but not probucol during oxidative modification. J Clin Invest 1991;87:597.
38. [38] Frei B, Stocker R, Ames BN. Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci 1988;85:9748.
39. [39] Bowry VW, Mohr D, Cleary J, Stocker R. Prevention of tocopherol mediated peroxidation in ubiquinol-10-free human low density lipoprotein. J Biol Chem 1995;270:5756.
40. [40] Esterbauer H, Jurgens G, Quehenberger O, Koller E. Autooxidation of human low density lipoproteins: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes. J Lipid Res 1987;28:495.