Alleles of Highly Homologous Rat T Cell Receptor β-Chain Variable Segments 8.2 and 8.4: Strain-Specific Expression, Reactivity to Superantigens, and Binding of the mAb R78

Journal of Immunology

Volumn 157, Issue 10, 1996, Pages 4436-4441

  Asmuß, Anne ^a   Hofmann, Kathrin ^a   Hochgrebe, Tim ^a   Giegerich, Gerhard ^b   Hünig, Thomas ^a   Herrmann, Thomas ^a,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c Institut fur Virologie und Immunbiologie   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; SUPERANTIGEN;

ALLELE; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY COMBINING SITE; ARTICLE; BIOSYNTHESIS; CHEMISTRY; FEMALE; GENETICS; IMMUNOLOGY; LEWIS RAT; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RAT; SPECIES DIFFERENCE;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; BINDING SITES, ANTIBODY; FEMALE; MOLECULAR SEQUENCE DATA; RATS; RATS, INBRED LEW; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SPECIES SPECIFICITY; SUPERANTIGENS;

EID: 0030588670     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Casanova, J. L., and J. L. Maryanski. 1993. Antigen-selected T-cell receptor diversity and self-non self homology. Immunol. Today 14:391.
2. Chien, Y. H., and M. M. Davis. 1993. How alpha beta T-cell receptors "see" peptide/MHC complexes. Immunol. Today 14:597.
3. + T cells. J. Exp. Med. 177:35.
4. Acha-Orbea, H., L. Steinman, and H. O. McDevill. 1989. T cell receptors in murine autoimmune diseases. Annu. Rev. Immunol. 7:37.
5. Kumar, V., D. H. Kono, J. L. Urban, and L. Hood. 1989. The T-cell receptor repertoire and autoimmune diseases. Annu. Rev. Immunol. 7:657.
6. Imrich, H., C. Kugler, N. Torres-Nagel, R. Dörries, and T. Hünig. 1995. Prevention and treatment of Lewis rat experimental allergic encephalomyelitis with a monoclonal antibody to the T cell receptor Vβ 8.2 segment. Eur. J. Immunol. 25:1960.
7. Gascoigne, N. R. J. 1993. Interaction of the T cell receptor with bacterial superantigens. Semin. Immunol. 5:13.
8. Marrack, P., G. M. Winslow, Y. Choi, M. Scherer, A. Pullen, J. White, and J. W. Kappler. 1993. The bacterial and mouse mammary tumor virus superantigens: two different families of proteins with the same functions. Immunol. Rev. 131:79.
9. Jardetzky, T. S., J. H. Brown, J. C. Gorga, L. J. Stern, R. G. Urban, Y. I. Chi, C. Stauffacher, J. L. Strominger, and D. C. Wiley. 1994. Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature 368:711.
10. Bentley, G. A., G. Boulot, K. Karjalainen, and R. A. Mariuzza. 1995. Crystal structure of the beta chain of a T cell antigen receptor. Science 267:1984.
11. Acha-Orbea, H., and H. R. MacDonald. 1995. Superantigens of mouse mammary tumor virus. Annu. Rev. Immunol. 13:459.
12. Choi, Y., A. Herman, D. DiGiusto, T. Wade, P. Marrack, and J. Kappler. 1990. Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens. Nature 346:471.
13. a. Cell 61:1365.
14. Bellio, M., Y. C. Lone, O. de la Calle-Martin, B. Malissen, J. P. Abastado, and P. Kourilsky. 1994. The V beta complementarity determining region 1 of a major histocompatibility complex (MHC) class I-restricted T cell receptor is involved in the recognition of peptide/MHC I and superantigen/MHC II complex. J. Exp. Med. 179:1087.
15. Patten, P. A., E. P Rock, T. Sonoda, B. D. S. G. Fazekas, J. L. Jorgensen, and M. M. Davis. 1993. Transfer of putative complementarity-determining region loops of the T cell receptor domains confers toxin but not peptide/MHC specificity. J. Immunol. 150:2281.
16. Herrmann, T., T. Hochgrebe, N. E. Torres-Nagel, B. T. Huber, and T. Hünig. 1994. Control of the rat T cell response to retroviral and bacterial superantigens by class II MHC products and Tcrb-V8.2 alleles. J. Immunol. 152:4300.
17. Surh, C. D., D. P. Gold, S. Wiley, D. B. Wilson, and J. Sprent. 1994. Rat T cell response to superantigens. I. V beta-restricted clonal deletion of rat T cells differentiating in rat→mouse chimeras. J. Exp. Med 179:57.
18. Gold, D. P., C. D. Surh, K. S. Sellins, K. Schroder, J. Sprent, and D. B. Wilson. 1994. Rat T cell responses to superantigens. II. Allelic differences in Vβ 8.2 and Vβ 8.5 chains determine responsiveness to staphylococcal enterotoxin B and mouse mammary tumor virus-encoded products. J. Exp. Med. 179:63.
19. Smith, L. R., D. H. Kono, and A. N. Theofilopolous. 1991. Complexity and sequence identification of 24 rat Vβ genes. J. Immunol. 147:375.
20. Blankenhorn, E. P., S. A. Stranford, A.-M. Mertin, and W. F. Hickey. 1995. Cloning of myelin-basic protein-reactive T cells from experimental allergic encephalomyelitis-resistant rat strain LER. J. Neuroimmunol. 59:173.
21. Hünig, T., H.-J. Wallny, J. K. Hartley, A. Lawetzky, and G. Tiefenthaler. 1989. A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. J. Exp. Med. 169:73.
22. Torres-Nagel, N. E., D. P. Gold, and T. Hünig. 1993. Identification of rat TCR Vβ 8.2, 8.5, and 10 gene products by monoclonal antibodies. Immunogenetics 37:304.
23. Kampinga, J., F. G. M. Kroese, G. H. Pol, P. Niewenhuis, F. Haag, P. B. Singh, B. Roser, and R. Aspinall. 1989. A monoclonal antibody to a determinant of the rat T cell antigen receptor expressed by a minor subset of T cells. Int. Immunol. 1:289.
24. Mason, D. W., R. P. Arthur, M. J. Dallman, J. R. Green, G. P. Spoickett, and M. L. Thomas. 1983. Functions of rat T-lymphocyte subsets isolated by means of monoclonal antibodies. Immunol. Rev. 74:57.
25. Fleischer, B., S. R. Gerardy, B. Metzroth, S. Carrel, and W. Köhler. 1991. An evolutionary conserved mechanism of T cell activation by microbial toxins: evidence for different affinities of T cell receptor-toxin interaction. J. Immunol. 146:11.
26. Herman, A., G. Croteau, R. P. Sekaly, J. Kappler, and P. Marrack. 1990. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J. Exp. Med. 172:709.
27. Jung, S., H. J. Schluesener, K. V. Toyka, and H. P. Hartung. 1991. T cell vaccination does not induce resistance to experimental autoimmune neuritis. J. Neuroimmunol. 35:1.
28. Chirgwin, J. M., A. E. Przbyla, R. J. MacDonald, and W. J. Ruffer. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294.
29. Gilman, M. 1993. Ribonuclease protection assay. In Current Protocols in Molecular Biology, Vol. 1. F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Strahl, eds. John Wiley and Sons, New York, pp. 4.7.1-4.7.8.
30. Candeias, S., R. S. Hardy, Y.-S. Li, and U. D. Staerz. 1994. T cell receptor Vβ 8.2 germ-line transcription: an early event of lymphocytes differentiation. Eur. J. Immunol. 24:3073.
31. Zhang, X.-M., T. R. Esch, L. Clark, S. Gregorian, A. Rostami, L. J. Otvos, and E. Heber-Katz. 1994. Neuritogenic Lewis rat T cells use Tcrb chains that include a new Tcrb-V8 family member. Immunogenetics 40:266.
32. Blankenhorn, E. P., S. Stranford, P. D. Smith, and W. F. Hickey. 1991. Genetic differences in the T cell receptor alleleles of LEW rats and the encephalomyelitis-resistant derivative, LER, and their impact on the inheritance of EAE resistance. Eur. J. Immunol. 21:2033.
33. Hashim, G., A. A. Vandenbark, D. P. Gold, T. Diamanduros, and H. Offner. 1991. T cell lines specific for an immunodominant epitope of human basic protein define an encephalotogenic determinant for experimental autoimmune encephalomyelitis resistant LOU/M rats. J. Immunol. 146:515.
34. Zhang, X.-M., and E. Heber-Katz. 1992. T cell receptor sequences from encephalotogenic T cells in adult Lewis rats suggest an early ontogenic origin. J. Immunol. 148:746.
35. Offner, H., M. Vainiene, D. P. Gold, W. Morrison, R.-Y. Wang, G. Hashim, and A. Vandenbark. 1991. Protection against experimental encephalomyelitis: idiotypic autoregulation induced by a nonencephaloenic T cell clone expressing a cross-reactive T cell receptor V gene. J. Immunol. 146:4165.
36. Chluba, J., C. Steeg, A. Becker, H. Weckerle, and J. T. Epplen. 1989. T cell receptor β chain usage in myelin basic protein-specific rat T lymphocytes. Eur. J. Immunol. 19:279.
37. Chou, H. S., S. J. Anderson, M. C. Louie, S. A. Godambe, S. A. Pozzi, M. R. Pozzi, M. A. Behlke, K. Huppi, and D. Y. Loh. 1987. Tandem linkage and unusual splicing of the T-cell receptor β-chain variable region genes. Proc. Natl. Acad. Sci. USA 84:1992.
38. Chothia, C., D. R. Boswell, and A. M. Lesk. 1988. The outline structure of the T-cell αβ receptor. EMBO J. 7:3745.