Chromosomal localization of the mouse and rat DNA double-strand break repair genes Ku p70 and Ku p80/XRCC5 and their mRNA expression in various mouse tissues

Genomics

Volumn 38, Issue 1, 1996, Pages 38-44

  Koike, Manabu ^a   Matsuda, Yoichi ^a   Mimori, Tsuneyo ^b   Harada, Yoshi Nobu ^a   Shiomi, Naoko ^a   Shiomi, Tadahiro ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; GENE PRODUCT; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 1; CHROMOSOME 15; CHROMOSOME 7; CHROMOSOME 9; DNA REPAIR; GENE EXPRESSION; GENE LOCATION; GENE LOCUS; GENETIC CONSERVATION; GENETIC LINKAGE; GENETIC TRANSCRIPTION; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY;

ANIMALIA; MURINAE;

EID: 0030588639     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0589     Document Type: Article

References (41)

1. Anderson, C. W., and Lees-Miller, S. P. (1992). The nuclear serine/ threonine protein kinase DNA-PK. Crit. Rev. Euk. Gene Expr. 2: 283-314.
2. Bishop, D. K., Paark, D., Xu, L., and Kleckner. (1992). DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69: 439-456.
3. Blunt, T., Finneie, N. J., Taccioli, G. E., Smith, G. C. M., Demengeot, J., Gottieb, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A., and Jackson, S. P. (1995). Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80: 813-823.
4. Boubnov, N. V., Hall, K. T., Wills, Z., Lee, S. E., He, D. M., Benjamin, D.M., Pulaski, C. R., Band, H., Reeves, W., Hendrickson, E. A., and Weaver, D. T. (1995). Complementation of the ionizing radiation sensitivity, DNA end binding and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen. Proc. Natl. Acad. Sci. USA 92: 890-894.
5. Cai, Q-Q., Plet, A., Imbert, J., Lafage-Pochitaloff, M., Cerdan, C., and Blanchard, J-M. (1994). Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues. Cytogenet. Cell Genet. 65: 221-227.
6. Chan, J. Y., Lerman, M. I., Prabhakar, B. S., Isozaki, O., Santisteban, P., Kuppers, R. C., Oates, E. L., Notkins, A. L., and Kohn, L. D. (1989). Cloning and characterization of a cDNA that encodes a 70-kd novel human thyroid autoantigen. J. Biol. Chem. 264: 3651-3654.
7. Chen, J. C., Park, M. S., Campbell, E., Oshimura, M., Liu, P., Zhao, Y., White, B. F., and Siciliano, M. J. (1992). Assignment of a human DNA double-strand break repair gene (XRCC5) to chromosome 2. Genomics 13: 1088-1094.
8. Falzon, M., and Kuff, E. L. (1992). The nucleotide sequence of a mouse cDNA encoding the 80 kDa subunit of the Ku (p70/p80) autoantigen. Nucleic Acids Res. 20: 3784.
9. Finne, N. J., Gottlieb, T. M., Blunt, T., Jeggo, P.A., and Jackson, S. P. (1995). DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 92: 320-324.
10. Giaccia, A., Weinstein, R., Hu, J., and Stamato, T. D. (1985). Cell cycle-dependent repair of double-strand DNA breaks in a γ-ray sensitivity Chinese hamster cell. Cell. Mol. Genet. 11: 485-491.
11. Gottlieb, T. M., and Jackson, S. P. (1993). The DNA-dependent protein kinase: Requirement for the DNA ends and association with Ku antigen. Cell 72: 131-142.
12. Hafezparast, M., Kaur, G. P., Zdzienicka, M., Athwal, R. S., Lehmann, A. R., and Jeggo, P. A. (1993). Subchromosomal localization of a gene (XRCC5) involved in double strand break repair to the region 2q34-36. Somat. Cell Mol. Genet. 19: 413-421.
13. Harada, Y.-N., Matsuda, Y., Shiomi, N., and Shiomi, T. (1995). Complementary DNA sequence and chromosomal localization of xpg, the mouse counterpart of human repair gene XPG/ERCC5. Genomics 28: 59-65.
14. Itoh, M., Hamatani, K., Komatsu, K., Araki, R., Takayama, K., and Abe, M. (1993). Human chromosome-8 (p12 → q22) complements radiosensitivity in the severe combined immune deficiency (scid) mouse. Radiat. Res. 134: 364-368.
15. Jeggo, P. A., and Kemp, L. M. (1983). X-ray-sensitive mutants of Chinese hamster ovary cell line: Isolation and cross-sensitivity to other DNA damaging agents. Mutat. Res. 254: 125-133.
16. Jeggo, P. A., Tesmor, J., and Chen, D. J. (1991). Genetic analysis of ionising radiation sensitive mutants of cultured mamalian cell lines. Mutat. Res. 254: 125-133.
17. Jeggo, P. A., Hafezparast, M., Thompson, A. F., Broughton, B. C., Kaur, G. P., Zdsienicka, M. Z., and Athwal, R. S. (1992). Localization of a DNA repair gene (XRCC5) involved in double-strand break rejoining to human chromosome 2. Proc. Natl. Acad. Sci. USA 89: 6423-6427.
18. Jones, N. J., Cox, R., and Thacker, J. (1988). Six complementation groups for ionising-radiation sensitivity in Chinese hamster cells. Mutat. Res. 193: 139-144.
19. Kirchgessner, C. U., Tosto, L. M., Biedermann, K. A., Kovacs, M., Araujo, D., Stanbridge, E. J., and Brown, J. M. (1993). Complementation of the radiosensitive phenotype in severe combined immunodeficient mice by human chromosome-8. Cancer Res. 53: 6011-6016.
20. Kirchgessner, C. U., Patil, C. K., Evans, J. W., Cuomo, C. A., Fried, L. M., Carter, T., Oettinger, M. A., and Brown, J. M. (1995). DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 267: 1178-1183.
21. Komatsu, K., Ohta, T., Jinno, Y., Niikawa, N., and Okumura, Y. (1993). Functional complementation in mouse - human radiation hybrids assigns the putative murine scid gene to the pericentric region of human chromosome-8. Hum. Mol. Genet. 2: 1031-1034.
22. Kurimasa, A., Nagata, Y., Shimizu, M., Emi, M., Nakamura, Y., and Oshimura, M. (1994). A human gene that restores the DNA-repair defect in scid mice is located on 8p11.1 → q11.1. Hum. Genet. 93: 21-26.
23. Lyon, M. F., and Kirby, M. C. (1994). Mouse chromosome atlas. Mouse Genome 92: 19-61.
24. Matsuda, Y., Harada, Y.-N., Natsuume-Sakai, S., Lee, K., Shiomi, T., and Chapman, V. M. (1992). Location of the mouse complement factor H gene (chf) by FISH analysis and replication R-banding. Cytogenet. Cell Genet. 61: 282-285.
25. Matsuda, Y., and Chapman, V. M. (1995). Application of fluorescence in situ hybridization in genome analysis of the mouse. Electrophoresis 16: 261-272.
26. Matsuda, Y., Habu, T., Hori, T., and Morita, T. (1996). Chromosome mapping of the mouse homologues of DMC1, the yeast meiosis-specific homologous recombination gene. Chromosome Res., in press.
27. Miller, R. D., Hogg, J., Ozaki, J. H., Gell, D., Jackson, S. P., and Riblet, R. (1995). Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus. Proc. Natl. Acad. Sci. USA 92: 10792-10795.
28. Mimori, T., Akizuki, M., Yamagata, H., Inada, S., Yoshida, S., and Homma, M. (1981). Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies from patients with polymyositis-scleroderma overlap. J. Clin. Invest. 68: 611-620.
29. Mimori, T., Hardin, J. A., and Steitz, J. A. (1986). Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. J. Biol. Chem. 261:2274-2278.
30. Peterson, S. R., Kurimasa, A., Oshimura, M., Dynan, W. S., Bradbury, E. M., and Chen, D. J. (1995). Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA 92: 3171-3174.
31. Porges, A. J., Ng, T., and Reeves, W. H. (1990). Antigenic determinants of the Ku (p70/p80) autoantigen are poorly conserved between species. J. Immunol. 145: 4222-4228.
32. Reeves, W. H., and Sthoeger, Z. M. (1989). Molecular cloning of cDNA encoding the p70 (Ku) Lupus autoantigen. J. Biol. Chem. 264: 5047-5052.
33. Seldin, M. F., Hunter, K., and Watson, M. L. (1993). Mouse chromosome 1. Mamm. Genome 4(SuppL): 10-30.
34. Sipley, J. D., Menninger, J. C., Hartley, K. O., Ward, D. C., Jackson, S. P., and Anderson, C. W. (1995). Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8. Proc. Natl. Acad. Sci. USA 92: 7515-7519.
35. Smider, V., Rathmell, W. K., Lieber, M. R., and Chu, G. (1994). Restration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 266: 288-291.
36. Taccioli, G. E., Gottlieb, T. M., Blunt, T., Preistley, A., Demengeot, J., Mizuta, R., Lehmann, A. R., Alt, F. W., Jackson, S. P., and Jeggo, P. A. (1994). Ku 80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265: 1442-1445.
37. Takahashi, E., Shiomi, N., and Shiomi, T. (1992). Precise localization of the excision repair gene ERCC5, to human chromosome 13q32.3-q33.1 by direct R-banding fluorescence in situ hybridization. Jpn. J. Cancer Res. 83: 1117-1119.
38. Takiguchi, Y., Kurimasa, A., Chen, F., Pardington, P. E., Kuriyama, T., Okinaka, R. T., Moyzis, R., and Chen, D. J. (1996). Genomic structure and chromosomal assignment of the mouse Ku70 gene. Genomics 35: 129-135.
39. Whitemore, G. F., Varghese, A. J., and Gulyas, S. (1989). Cell cycle responses of two X-ray sensitive mutants defective in DNA repair. Int. J. Radiat. Biol. 56: 657-665.
40. Yamada, Y., Kuramato, T., and Serikawa, T. (1994). A rat genetic linkage map and comparative maps for mouse or human homologous rat genes. Mamm. Genome 5: 63-83.
41. Zdzienicka, M. Z. (1995). Mammalian mutants defective in the response to ionizing radiation-induced DNA damage. Mutat. Res. 336: 203-213.