-
1
-
-
0027273684
-
Somatic mutation and memory
-
Berek, C. 1993. Somatic mutation and memory. Curr. Opin. Immunol. 5:218.
-
(1993)
Curr. Opin. Immunol.
, vol.5
, pp. 218
-
-
Berek, C.1
-
3
-
-
0029888843
-
Molecular basis of somatic hypermutation of immunoglobulin genes
-
Storb, U. 1996. Molecular basis of somatic hypermutation of immunoglobulin genes. Curr. Opin. Immunol. 8:206.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 206
-
-
Storb, U.1
-
4
-
-
2342459088
-
Somatic hypermutation of an immunoglobulin transgene in κ transgenic mice
-
O'Brien, R. L., R. L. Brinster, and U. Storb. 1981. Somatic hypermutation of an immunoglobulin transgene in κ transgenic mice. Nature 32:405.
-
(1981)
Nature
, vol.32
, pp. 405
-
-
O'Brien, R.L.1
Brinster, R.L.2
Storb, U.3
-
5
-
-
0025900034
-
Somatic hypermutation of immunoglobulin κ may depend on sequences 3′ of Cκ and occurs on passenger transgenes
-
Sharpe, M. J., C. Milstein, J. M. Jarvis, and M. S. Neuberger. 1991. Somatic hypermutation of immunoglobulin κ may depend on sequences 3′ of Cκ and occurs on passenger transgenes. EMBO J. 10:2139.
-
(1991)
EMBO J.
, vol.10
, pp. 2139
-
-
Sharpe, M.J.1
Milstein, C.2
Jarvis, J.M.3
Neuberger, M.S.4
-
6
-
-
0028270307
-
Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role of the intron enhancer/matrix attachment region
-
Betz, A. G., C. Milstein, A. González-Fernández, R. Pannell, T. Larson, and M. S. Neuberger, 1994. Elements regulating somatic hypermutation of an immunoglobulin κ gene: critical role of the intron enhancer/matrix attachment region. Cell 77:239.
-
(1994)
Cell
, vol.77
, pp. 239
-
-
Betz, A.G.1
Milstein, C.2
González-Fernández, A.3
Pannell, R.4
Larson, T.5
Neuberger, M.S.6
-
7
-
-
0030063726
-
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
-
Peters, A., and U. Storb. 1996. Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity 4:57.
-
(1996)
Immunity
, vol.4
, pp. 57
-
-
Peters, A.1
Storb, U.2
-
8
-
-
0027364313
-
Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin κ light-chain transgenes
-
González-Fernández, A., and C. Milstein. 1993. Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin κ light-chain transgenes. Proc. Natl. Acad Sci. USA 90:9862.
-
(1993)
Proc. Natl. Acad Sci. USA
, vol.90
, pp. 9862
-
-
González-Fernández, A.1
Milstein, C.2
-
9
-
-
0028983486
-
Somatic hypermutation of VHS107 genes is not associated with gene conversion among family members
-
Rogerson, B. J. 1995. Somatic hypermutation of VHS107 genes is not associated with gene conversion among family members. Int. Immunol. 7:1225.
-
(1995)
Int. Immunol.
, vol.7
, pp. 1225
-
-
Rogerson, B.J.1
-
10
-
-
0024362521
-
2 transgene
-
2 transgene. J. Exp. Med. 169:1911.
-
(1989)
J. Exp. Med.
, vol.169
, pp. 1911
-
-
Hagman, J.1
Lo, D.2
Doglio, L.T.3
Hackett Jr., J.4
Rudin, C.M.5
Haasch, D.6
Brinster, R.7
Storb, U.8
-
11
-
-
0028168657
-
Expression of λ and κ genes can occur in all B cells and is initiated around the same pre-B-cell developmental stage
-
Doglio, L., J. Y. Kim, G. Bozek, and U. Storb. 1994. Expression of λ and κ genes can occur in all B cells and is initiated around the same pre-B-cell developmental stage. Dev. Immunol. 4:13.
-
(1994)
Dev. Immunol.
, vol.4
, pp. 13
-
-
Doglio, L.1
Kim, J.Y.2
Bozek, G.3
Storb, U.4
-
12
-
-
0019444879
-
Dual expression of lambda genes in the MOPC-315 plasmacytoma
-
Bothwell, A. L., M. Paskind, R. C. Schwarz, G. E. Sonenshein, M. L. Gefter, and D. Baltimore. 1981. Dual expression of lambda genes in the MOPC-315 plasmacytoma. Nature 290:65.
-
(1981)
Nature
, vol.290
, pp. 65
-
-
Bothwell, A.L.1
Paskind, M.2
Schwarz, R.C.3
Sonenshein, G.E.4
Gefter, M.L.5
Baltimore, D.6
-
13
-
-
0028217720
-
Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes
-
Ford, J. E., M. G. McHeyzer-Williams, and M. R. Lieber. 1994. Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes. Gene 142:279.
-
(1994)
Gene
, vol.142
, pp. 279
-
-
Ford, J.E.1
McHeyzer-Williams, M.G.2
Lieber, M.R.3
-
14
-
-
0025788241
-
High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrocaccus furiosus
-
Lundberg, K. S., D. D. Shoemaker, M. W. W. Adams, J. M. Short, J. A. Sorge, and E. J. Mathur. 1991. High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrocaccus furiosus. Gene 108:1.
-
(1991)
Gene
, vol.108
, pp. 1
-
-
Lundberg, K.S.1
Shoemaker, D.D.2
Adams, M.W.W.3
Short, J.M.4
Sorge, J.A.5
Mathur, E.J.6
-
15
-
-
0004032583
-
-
U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Bethesda, MD
-
Kabat, E. A., T. T. Wu, H. M. Perry, K. S. Gottesman, and C. Foeller, eds. 1991. Sequences of Proteins of Immunological Interest, 5th Ed., Vol. II. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Bethesda, MD.
-
(1991)
Sequences of Proteins of Immunological Interest, 5th Ed.
, vol.2
-
-
Kabat, E.A.1
Wu, T.T.2
Perry, H.M.3
Gottesman, K.S.4
Foeller, C.5
-
16
-
-
0028577994
-
Somatic mutation of immunoglobulin λ chains: A segment of the major intron hypermutates as much as the complementarity-determining regions
-
Gonzalez-Fernandez, A., S. K. Gupta, R. Pannell, M. S. Neuberger, and C. Milstein. 1994. Somatic mutation of immunoglobulin λ chains: a segment of the major intron hypermutates as much as the complementarity-determining regions. Proc. Natl. Acad. Sci. USA 91:12614.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12614
-
-
Gonzalez-Fernandez, A.1
Gupta, S.K.2
Pannell, R.3
Neuberger, M.S.4
Milstein, C.5
-
17
-
-
0027531851
-
B cell development in mice that lack one or both immunoglobulin κ light chain genes
-
Chen, J., M. Trounstine, C. Kurahara, F. Young, C. Kuo, Y. Xu, J. F. Loring, F. W. Alt, and D. Huszar. 1993. B cell development in mice that lack one or both immunoglobulin κ light chain genes. EMBO J. 12:821.
-
(1993)
EMBO J.
, vol.12
, pp. 821
-
-
Chen, J.1
Trounstine, M.2
Kurahara, C.3
Young, F.4
Kuo, C.5
Xu, Y.6
Loring, J.F.7
Alt, F.W.8
Huszar, D.9
-
19
-
-
0028063853
-
Comparison of somatic mutation frequency among immunoglobulin genes
-
Motoyama, N., T. Miwa, Y. Suzuki, H. Okada, and T. Azuma. 1994. Comparison of somatic mutation frequency among immunoglobulin genes. J. Exp. Med. 179: 395.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 395
-
-
Motoyama, N.1
Miwa, T.2
Suzuki, Y.3
Okada, H.4
Azuma, T.5
-
20
-
-
0027227311
-
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
-
Betz, A. G., M. S. Neuberger, and C. Milstein. 1993. Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol. Today 14:405.
-
(1993)
Immunol. Today
, vol.14
, pp. 405
-
-
Betz, A.G.1
Neuberger, M.S.2
Milstein, C.3
-
21
-
-
0023652377
-
Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses
-
Siekevitz, M., C. Kocks, K. Rajewsky, and R. Dildrop. 1987. Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses. Cell 48:757.
-
(1987)
Cell
, vol.48
, pp. 757
-
-
Siekevitz, M.1
Kocks, C.2
Rajewsky, K.3
Dildrop, R.4
-
22
-
-
0028171011
-
Age-related decrease in the proportion of germinal center B cells from mouse Peyer's patches is accompanied by an accumulation of somatic mutations in the immunoglobulin genes of germinal center B cells
-
González-Fernández, A., D. Gilmore, and C. Milstein. 1994. Age-related decrease in the proportion of germinal center B cells from mouse Peyer's patches is accompanied by an accumulation of somatic mutations in the immunoglobulin genes of germinal center B cells. Eur. J. Immunol. 24:2918.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 2918
-
-
González-Fernández, A.1
Gilmore, D.2
Milstein, C.3
-
23
-
-
0026060520
-
Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication
-
Rogerson, B., J. Hackett, Jr., A. Peters, D. Haasch, and U. Storb. 1991. Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication. EMBO J. 10:4331.
-
(1991)
EMBO J.
, vol.10
, pp. 4331
-
-
Rogerson, B.1
Hackett Jr., J.2
Peters, A.3
Haasch, D.4
Storb, U.5
-
24
-
-
0029927054
-
The mechanism of somatic hypermutation studied with transgenic and transfected target genes
-
Storb, U., A. Peters, E. Klotz, B. Rogerson, and J. Hackett, Jr. 1996. The mechanism of somatic hypermutation studied with transgenic and transfected target genes. Semin. Immunol. 8:131.
-
(1996)
Semin. Immunol.
, vol.8
, pp. 131
-
-
Storb, U.1
Peters, A.2
Klotz, E.3
Rogerson, B.4
Hackett Jr., J.5
-
25
-
-
0029067875
-
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation
-
Yélamos, J., N. Klix, B. Goyenechea, F. Lozano, Y. L. Chui, A. González-Fernández, R. Pannell, M. S. Neuberger, and C. Milstein. 1995. Targeting of non-Ig sequences in place of the V segment by somatic hypermutation. Nature 376:225.
-
(1995)
Nature
, vol.376
, pp. 225
-
-
Yélamos, J.1
Klix, N.2
Goyenechea, B.3
Lozano, F.4
Chui, Y.L.5
González-Fernández, A.6
Pannell, R.7
Neuberger, M.S.8
Milstein, C.9
-
26
-
-
0022553738
-
Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites
-
Cockerill, P. N., and W. T. Garrard. 1986. Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites. Cell 44:273.
-
(1986)
Cell
, vol.44
, pp. 273
-
-
Cockerill, P.N.1
Garrard, W.T.2
-
27
-
-
0344413285
-
Dysfunction of chromosomal loop attachment sites: Illegitimate recombination linked to matrix association regions and topoisomerase II
-
Sperry, A. O., V. C. Blasquez, and W. T. Garrard. 1989. Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II. Proc. Natl. Acad. Sci. USA 86:5497.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5497
-
-
Sperry, A.O.1
Blasquez, V.C.2
Garrard, W.T.3
-
28
-
-
0023654621
-
The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements
-
Cockerill, P. N., M.-H. Yuen, and W. T. Garrard. 1987. The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements. J. Biol. Chem. 262:5394.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 5394
-
-
Cockerill, P.N.1
Yuen, M.-H.2
Garrard, W.T.3
-
29
-
-
0024790860
-
Immunoglobulin κ gene expression after stable integration. II. Role of the intronic MAR and enhancer in transgenic mice
-
Xu, M., R. E. Hammer, V. C. Blasquez, S. L. Jones, and W. T. Garrard. 1989. Immunoglobulin κ gene expression after stable integration. II. Role of the intronic MAR and enhancer in transgenic mice. J. Biol. Chem. 264:21190.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 21190
-
-
Xu, M.1
Hammer, R.E.2
Blasquez, V.C.3
Jones, S.L.4
Garrard, W.T.5
-
30
-
-
0027963309
-
Dependence of enhancer-mediated transcription of the immunoglobulin μ gene on nuclear matrix attachment regions
-
Forrester, W. C., C. van Genderen, T. Jenuwein, and R. Grosschedl. 1994. Dependence of enhancer-mediated transcription of the immunoglobulin μ gene on nuclear matrix attachment regions. Science 265:1221.
-
(1994)
Science
, vol.265
, pp. 1221
-
-
Forrester, W.C.1
Van Genderen, C.2
Jenuwein, T.3
Grosschedl, R.4
-
31
-
-
0024494831
-
Physical linkage of mouse λ genes by pulsed-field gel electrophoresis suggests that the rearrangement process favors proximate target sequences
-
Storb, U., D. Haasch, B. Arp, P. Sanchez, P.-A. Cazenave, and J. Miller. 1989. Physical linkage of mouse λ genes by pulsed-field gel electrophoresis suggests that the rearrangement process favors proximate target sequences. Mol. Cell. Biol. 9:711.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 711
-
-
Storb, U.1
Haasch, D.2
Arp, B.3
Sanchez, P.4
Cazenave, P.-A.5
Miller, J.6
-
32
-
-
0025347851
-
Lack of somatic mutation in a κ light chain transgene
-
Sharpe, M. J., M. Neuberger, R. Pannell, M. A. Surani, and C. Milstein. 1990. Lack of somatic mutation in a κ light chain transgene. Eur. J. Immunol. 20:1379.
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 1379
-
-
Sharpe, M.J.1
Neuberger, M.2
Pannell, R.3
Surani, M.A.4
Milstein, C.5
-
33
-
-
0030030268
-
Expanding the role of Peyer's patches in B-cell ontogeny
-
Griebel, P. J., and W. R. Hein. 1996. Expanding the role of Peyer's patches in B-cell ontogeny. Immunol. Today 17:30.
-
(1996)
Immunol. Today
, vol.17
, pp. 30
-
-
Griebel, P.J.1
Hein, W.R.2
-
34
-
-
0027510316
-
Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer
-
Azuma, T., N. Motoyama, L. E. Fields, and D. Y. Loh. 1993. Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer. Int. Immunol. 5:121.
-
(1993)
Int. Immunol.
, vol.5
, pp. 121
-
-
Azuma, T.1
Motoyama, N.2
Fields, L.E.3
Loh, D.Y.4
-
35
-
-
0026633095
-
Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism
-
Hackett, J., Jr., C. Stebbins, B. Rogerson, M. M. Davis, and U. Storb. 1992. Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism. J. Exp. Med. 176:225.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 225
-
-
Hackett Jr., J.1
Stebbins, C.2
Rogerson, B.3
Davis, M.M.4
Storb, U.5
-
36
-
-
0027960893
-
Locus-specific somatic hypermutation in germinal centre T cells
-
Zheng, B., W. Xue, and G. Kelsoe. 1994, Locus-specific somatic hypermutation in germinal centre T cells. Nature 372:556.
-
(1994)
Nature
, vol.372
, pp. 556
-
-
Zheng, B.1
Xue, W.2
Kelsoe, G.3
-
37
-
-
0028177913
-
1 transgene under the control of a heavy chain promoter and enhancer does not undergo somatic hypermutation
-
1 transgene under the control of a heavy chain promoter and enhancer does not undergo somatic hypermutation. Eur. J Immunol. 24:1649.
-
(1994)
Eur. J Immunol.
, vol.24
, pp. 1649
-
-
Hengstschläger, M.1
Willams, M.2
Maizels, N.3
-
38
-
-
0027410278
-
Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: Implications for the location of cis-acting elements required for somatic mutation
-
Giusti, A. M., and T. Manser. 1993. Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation. J. Exp. Med. 177:797.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 797
-
-
Giusti, A.M.1
Manser, T.2
-
39
-
-
0021930325
-
Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements
-
Grosschedl, R., and D. Baltimore. 1985. Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements. Cell 41: 885.
-
(1985)
Cell
, vol.41
, pp. 885
-
-
Grosschedl, R.1
Baltimore, D.2
-
40
-
-
0022346983
-
Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence
-
Mason, J. O., G. T. Williams, and M. S. Neuberger. 1985. Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence. Cell 41:479.
-
(1985)
Cell
, vol.41
, pp. 479
-
-
Mason, J.O.1
Williams, G.T.2
Neuberger, M.S.3
-
41
-
-
0028232693
-
Lipopolysaccharide-dependent transactivation of the temporally regulated immunoglobulin heavy chain 3′ enhancer
-
Arulampalam, V., P. A. Grant, A. Samuelsson, U. Lendahl, and S. Pettersson. 1994. Lipopolysaccharide-dependent transactivation of the temporally regulated immunoglobulin heavy chain 3′ enhancer. Eur. J. Immunol. 24:1671.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1671
-
-
Arulampalam, V.1
Grant, P.A.2
Samuelsson, A.3
Lendahl, U.4
Pettersson, S.5
|