Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A) - A gene involved in fat metabolism located at 11p15.1

Genomics

Volumn 37, Issue 2, 1996, Pages 211-218

  Löbbert, Ralf W ^a   Winterpacht, Andreas ^a   Seipel, Barbara ^a   Zabel, Bernhard U ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; CYCLIC GMP; FAT; GENE PRODUCT; INSULIN; PHOSPHODIESTERASE I; RNA;

ADIPOSE TISSUE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 11P; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE EXPRESSION; GENE MAPPING; HAMSTER; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRID CELL; LIPID METABOLISM; MOLECULAR CLONING; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORTHERN BLOTTING; OBESITY; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY;

ANIMALIA; CRICETINAE;

EID: 0030588128     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0544     Document Type: Article

References (48)

1. Aguilar-Bryan, L., Nichols, C. G., Wechsler, S. W., IV, Clement, J. P., III, Boyd, A. E., González, G., Herrera-Sosa, H., Nguy, K., Bryan, J., and Nelson, D. A. (1995). Cloning of the β cell high-affinity sulfonylurea receptor: A regulator of insulin secretion. Science 268: 423-426.
2. Altschul, S. F., Gish, W., Miller, W., Meyers, E. H., and Lipman, D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215: 403-410.
3. Barnett, A., Eff, C., Leslie, R. D. G., and Pyke, D. A. (1981). Diabetes in identical twins. Diabetologia 20: 87-93.
4. Bouchard, C., and Pérusse, L. (1993). Genetics of obesity. Annu. Rev. Nutr. 13: 337-354.
5. Boyes, S., and Loten, E. G. (1989). Insulin and lipolytic hormones stimulate the same phosphodiesterase isoform in rat adipose tissue. Biochem. Biophys. Res. Commun. 162: 814-820.
6. Buckler, A. J., Chang, D. D., Graw, S. L., Brook, D., Haber, D. A., Sharp, P. A., and Housman, D. E. (1991). Exon amplification: a strategy to isolate mammalian genes based on RNA splicing. Proc. Natl. Acad. Sci. USA 88: 4005-4009.
7. Chaffanet, M., Baens, M., Aerssens, J., Schoenmakers, E., Cassiman, J. J., and Marynen, P. (1995). Mapping of an ordered set of 14 cosmids to human chromosome 12p by two-color in situ hybridization. Cytogenet. Cell Genet. 69: 27-32.
8. Charbonneau, H. (1990). Structure-function relationship among cyclic nucleotide phosphodiesterases. In "Cyclic Nucleotide Phosphodiesterases: Structure, Regulation, and Drug Action" (Beavo, J., and Houslay, M., Eds) pp. 267-296, Wiley, Chichester, UK.
9. Church, D. M., Stotler, C. J., Rutter, J. L., Murrell, J. R., Trofatter, J. A., and Buckler, A. J. (1994). Isolation of genes from complex sources of mammalian genomic DNA using exon amplification. Nature Genet. 6: 98-104.
10. Church, G. M., and Gilbert, W. (1984). Genomic sequencing. Proc. Natl. Acad. Sci. USA 81: 1991-1995.
11. Elks, M. L., and Manganiello, V. C. (1985). Antilipolytic action of insulin: Role of cAMP phosphodiesterase activation. Endocrinology 116: 2119-2121.
12. Eriksson, H., Ridderstrale, M., Degerman, E., Ekholm, D., Smith, C. J., Manganiello, V. C., Belfrage, P., and Tornqvist, H. (1995). Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin. Biochim. Biophys. Acta 1266: 101-107.
13. Friedman, J. M., Leibel, R. L., and Bahary, N. (1991). Molecular mapping of obesity genes. Mamm. Genom. 1: 130-144.
14. Galli, J., Li, L.-S., Glaser, A., Östenson, C.-G., Jiao, H., Fakhrai-Rad, H., Jacob, H. J., Lander, E. S., and Luthman, H. (1996). Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. Nature Genet. 12: 31-37.
15. Gauguier, D., Froguel, P., Parent, V., Bernard, C., Bihoreau, M.-T., Portha, B., James, M. R., Penicaud, L., Lathrop, M., and Ktorza, A. (1996). Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nature Genet. 12: 38-43.
16. Genetics Computer Group (1991). "Program Manual for the GCG Package," 575 Science Drive, Madison, WI 53711.
17. Glaser, T., Housman, D. E., Lewis, W. H., Gerhard, D., and Jones, C. (1989). A fine-structure deletion map of human chromosome 11p: Analysis of J1 series hybrids. Somat. Cell Mol. Genet. 15: 477-501.
18. Groop, L. C., Bonadonna, R. C., DelPrato, S., Ratheiser, K., Zyck, D., Ferrannini, E., and DeFronzo, R. A. (1989). Glucose and free fatty acid metabolism in non-insulin dependent diabetes mellitus. J. Clin. Invest. 84: 205-213.
19. Higgins, M. J., Smilinch, N. J., Sait, S., Koenig, A., Pongratz, J., Gessler, M., Richard, C. W., III, James, M. R., Sanford, J. P., Kim, B. W., Cattelane, J., Nowak, N. J., Winterpacht, A., Zabel, B. U., Munroe, D. J., Bric, E., Housman, D. E., Jones, C., Nakamura, Y., Gerhard, D. S., and Shows, T. B. (1994). An ordered NotI fragment map of human chromosome band 11p15. Genomics 23: 211-222.
20. KATP : An inward rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170.
21. Kasuya, J., Goko, H., and Fujita-Yamaguchi, Y. (1995). Multiple transcripts for the human cardiac form of the cGMP-inhibited cAMP phosphodiesterase. J. Biol. Chem. 270: 14305-14312.
22. Kleyn, P. W., Fan, W., Kovats, S. G., Lee, J. J., Pulido, J. C., Wu, Y., Berkenmeier, L. R., Misumi, D. J., Holmgren, L., Charlat, O., Woolf, E. A., Tayber, O., Brody, T., Shu, P., Hawkins, F., Kennedy, B., Baldini, L., Ebeling, C., Alperin, G. D., Deeds, J., Lakey, N. D., Culpepper, J., Chen, H., Glücksmann-Kuis, M. A., Carlson, G. A., Duyk, G. M., and Moore, K. J. (1996). Identification and characterization of the mouse obesity gene tubby: A member of a novel gene family. Cell 85: 281-290.
23. Knowler, W. C., Pettitt, D. J., Saad, M. F., and Bennett, P. H. (1990). Obesity in the Pima Indians: Incidence, risk factors and pathogenesis. Diabetes Metab. Rev. 6: 1-27.
24. Kolterman, O. G., Gray, R. S., Griffin, J., Bustein, P., Insel, J., Scarlett, J. A., and Olefsky, J. M. (1981). Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. J. Clin. Invest. 68: 957-969.
25. Lemieux, N., Dutrillaux, B., and Biegas-Péquignot, E. (1992). A simple method for simultaneous R-or G-banding and fluorescence in situ hybridization of small copy genes. Cytogenet. Cell Genet. 59: 311-312.
26. Manganiello, V. C., Taira, M., Degerman, E., and Belfrage, P. (1995). Type III cGMP-inhibited cyclic nucleotide phophodiesterases. Cell Signal. 7: 445-455.
27. Marchuck, D., Drumm, M., Saulino, A., and Collins, F. S. (1990). Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products. Nucleic Acids Res. 19: 1154.
28. Mason, P. J., Enver, T., Wilkinson, D., and Williams, G. J. (1993). Assay of gene transcription in vivo. In "Gene Transcription: A Practical Approach" (Hames, B. D., and Higgins, S. J., Eds.) Oxfort Univ. Press, London.
29. Meacci, E., Taira, M., Moos, M., Jr., Smith, C. J., Movsesian, M. A., Degerman, E., Belfrage, P., and Manganiello, V. (1992). Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase. Proc. Natl. Acad. Sci. USA 89: 3721-3725.
30. Munroe, D. J., Haas, M., Bric, E., Whitton, T., Aburatani, H., Hunter, K., Ward, D., and Housman, D. E. (1994). IRE-Bubble PCR: A rapid method for efficient and representative amplification of human genomic DNA sequences from complex sources. Genomics 19: 506-514.
31. Newman, B., Selby, J. V., King, M.-C., Slemenda, C., Fabsitz, R., and Friedman, G. D. (1987). Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins. Diabetologia 23: 763-768.
32. Permutt, M. A., and Ghosh, S. (1996). Rat model contributes new loci for NIDDM susceptibility in man. Nature Genet. 12: 4-6.
33. Rascón, A., Degerman, E., Taira, M., Meacci, E., Smith, C. J., Manganiello, V., Belfrage, P., and Tornqvist, H. (1994). Identification of the phosphorylation site in vitro for cAMP-dependent protein kinase on the rat adipocyte cGMP-inhibited cAMP phosphodiesterase. J. Biol. Chem. 269: 11962-11966.
34. Reinhardt, R. R., Chin, E., Zhou, J., Taira, M., Murata, T., and Manganiello, V. C. (1995). Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases. J. Clin. Invest. 95: 1528-1538.
35. Rich, S. S. (1990). Mapping genes in diabetes. Diabetes 39: 1315-1319.
36. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). In "Molecular Cloning: A Laboratory Manual," 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
37. Schmitz-Peiffer, C., Reeves, M. L., and Denton, R. M. (1992). Characterization of the cyclic nucleotide phosphodiesterase isoenzymes present in rat epididymal fat cells. Cell Signal. 4: 37-49.
38. Seidin, M. F., Mott, D., Bhat, D., Petro, A., Kuhn, C. M., Kingsmore, S. F., Bogardus, C., Opara, E., Feinglos, M. N., and Surwit, R. S. (1994). Glycogen synthase: A putative locus for diet-induced hyperglycemia. J. Clin. Invest. 94: 269-276.
39. m cAMP phosphodiesterase in regulation of cAMP-dependent protein kinase and lipolysis in rat adipocytes. Mol. Pharmacol. 35: 381-386.
40. Smith, C. J., Vasta, V., Degerman, E., Belfrage, P., and Manganiello, V. C. (1991). Hormone-sensitive cyclic GMP-inhibited cyclic AMP phosphodiesterase in rat adipocytes. J. Biol. Chem. 266: 13385-13390.
41. Sorensen, T. I. A. (1995). The genetics of obesity. Metabolism 44(Suppl 3): 4-6.
42. Taira, M., Hockman, S. C., Calvo, J. C., Taira, M., Belfrage, P., and Manganiello, V. C. (1993). Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase. J. Biol. Chem. 268: 18573-18579.
43. Thäte, C., Pongratz, J., König, A., Klamt, B., Tsaoussidou, S., Higgins, M., Shows, T., Jones, C., and Gessler, M. (1995). CpG island clones for chromosome 11p - a resource for mapping and gene identification. Mamm. Genom. 6: 421-425.
44. Thomas, P. M., Cote, G. J., Wohllk, N., Haddad, B., Mathew, P. B., Rabl, W., Aguilar-Bryan, L., Gagel, R. F., and Bryan, J. (1995). Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science 268: 426-429.
45. Walker, M. (1995). Obesity, insulin resistance, and its link to non-insulin-dependent diabetes mellitus. Metabolism 44(Suppl 3): 18-20.
46. Walker, M., Agius, L., Orskov, H., and Alberti, K. G. M. M. (1993). Peripheral and hepatic insulin sensitivity in non-insulin-dependent diabetes mellitus: Effect of nonesterified fatty acids. Metabolism 42: 601-608.
47. Warden, C. H., Fisler, J. S., Shoemaker, S. M., Wen, P-Z., Svenson, K. L., Pace, M. J., and Lusis, A. J. (1995). Identification of four chromosomal loci determining obesity in a multifactorial mouse model. J. Clin. Invest. 95: 1545-1552.
48. Wesslau, C., Eriksson, J. W., and Smith, U. (1993). Cellular cyclic AMP levels modulate insulin sensitivity and responsiveness - evidence against a significant role of Gi in insulin signal transduction. Biochem. Biophys. Res. Commun. 196: 287-293.