메뉴 건너뛰기




Volumn 157, Issue 6, 1996, Pages 2728-2735

Disturbed Myeloperoxidase-Dependent Activity of Neutrophils in Cystic Fibrosis Homozygotes and Heterozygotes, and Its Correction by Amiloride

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; PEROXIDASE;

EID: 0030587191     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (92)

References (50)
  • 1
    • 0002314552 scopus 로고
    • Cystic fibrosis
    • R. Scriver, A. L. Beaudet, W. S. Ly, and D. Valle, eds. McGraw-Hill, New York
    • Boat, T. F., M. J. Welsh, and A. L. Beaudet. 1989. Cystic fibrosis. In The Metabolic Basis of Inherited Disease. R. Scriver, A. L. Beaudet, W. S. Ly, and D. Valle, eds. McGraw-Hill, New York, p. 2649.
    • (1989) The Metabolic Basis of Inherited Disease , pp. 2649
    • Boat, T.F.1    Welsh, M.J.2    Beaudet, A.L.3
  • 3
    • 0027162649 scopus 로고
    • Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
    • Welsh, M. J., and A. E. Smith. 1993. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73:1251.
    • (1993) Cell , vol.73 , pp. 1251
    • Welsh, M.J.1    Smith, A.E.2
  • 4
    • 0001278692 scopus 로고
    • Infection and inflammation in cystic fibrosis
    • P. B. Davis, ed. Marcel Dekker, New York
    • Konstan, M. W., and M. Berger. 1993. Infection and inflammation in cystic fibrosis. In Cystic Fibrosis. P. B. Davis, ed. Marcel Dekker, New York, p. 219.
    • (1993) Cystic Fibrosis , pp. 219
    • Konstan, M.W.1    Berger, M.2
  • 6
    • 0029286816 scopus 로고
    • Cystic fibrosis lung inflammation: Early, sustained and severe
    • Cantin, A. 1995. Cystic fibrosis lung inflammation: early, sustained and severe. Am. J. Respir. Crit. Care Med. 151:939.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.151 , pp. 939
    • Cantin, A.1
  • 7
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss, S. J. 1989. Tissue destruction by neutrophils. N. Engl. J. Med. 320:365.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 365
    • Weiss, S.J.1
  • 8
    • 0027998135 scopus 로고
    • The role of neutrophil elastase in chronic inflammation
    • Döring, G. 1994. The role of neutrophil elastase in chronic inflammation. Am. J. Respir. Crit. Care Med. 150:S114.
    • (1994) Am. J. Respir. Crit. Care Med. , vol.150
    • Döring, G.1
  • 9
    • 0015524885 scopus 로고
    • Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity
    • Allen, R. C., R. L. Stjernholm, and R. H. Steele. 1972. Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity. Biochem. Biophys. Res. Commun. 47:679.
    • (1972) Biochem. Biophys. Res. Commun. , vol.47 , pp. 679
    • Allen, R.C.1    Stjernholm, R.L.2    Steele, R.H.3
  • 10
    • 0017834531 scopus 로고
    • Oxygen-dependent microbial killing by phagocytes
    • Babior, B. M. 1978. Oxygen-dependent microbial killing by phagocytes. N. Engl. J. Med. 298:659.
    • (1978) N. Engl. J. Med. , vol.298 , pp. 659
    • Babior, B.M.1
  • 11
    • 0023484511 scopus 로고
    • Neutrophil activation on biological surfaces: Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes
    • Nathan, C. F. 1987. Neutrophil activation on biological surfaces: massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. J. Clin. Invest. 80:1550.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1550
    • Nathan, C.F.1
  • 12
    • 0014292067 scopus 로고
    • Myeloperoxidase-halide-hydrogen peroxide anti-bacterial system
    • Klebanoff, S. J. 1969. Myeloperoxidase-halide-hydrogen peroxide anti-bacterial system. J. Bacteriol. 95:2131.
    • (1969) J. Bacteriol. , vol.95 , pp. 2131
    • Klebanoff, S.J.1
  • 13
    • 0016634037 scopus 로고
    • Halide dependence of the myeloperoxidase-mediated antimicrobial system of the polymorphonuclear leukocyte in the phenomenon of electronic excitation
    • Allen, R. C. 1975. Halide dependence of the myeloperoxidase-mediated antimicrobial system of the polymorphonuclear leukocyte in the phenomenon of electronic excitation. Biochem. Biophys. Res. Commun. 63:675.
    • (1975) Biochem. Biophys. Res. Commun. , vol.63 , pp. 675
    • Allen, R.C.1
  • 14
    • 0026762871 scopus 로고
    • Intracellular singlet oxygen generation by phagocytosing neutrophils in response to particles coated with a chemical trap
    • Steinbeck, M. J., A. U. Khan, and M. J. Karnovsky. 1992. Intracellular singlet oxygen generation by phagocytosing neutrophils in response to particles coated with a chemical trap. J. Biol. Chem. 267:13425.
    • (1992) J. Biol. Chem. , vol.267 , pp. 13425
    • Steinbeck, M.J.1    Khan, A.U.2    Karnovsky, M.J.3
  • 15
    • 0016798148 scopus 로고
    • Chlorinating ability of human phagocytosing leukocytes
    • Zgliczynski, J. M., and T. Stelmaszynska. 1975. Chlorinating ability of human phagocytosing leukocytes. Eur. J. Biochem. 56:157.
    • (1975) Eur. J. Biochem. , vol.56 , pp. 157
    • Zgliczynski, J.M.1    Stelmaszynska, T.2
  • 16
    • 0020574002 scopus 로고
    • Long-lived oxidants generated by human neutrophils: Characterization and bioactivity
    • Weiss, S. J., M. B. Lampert, and S. T. Test. 1983. Long-lived oxidants generated by human neutrophils: characterization and bioactivity. Science 222:623.
    • (1983) Science , vol.222 , pp. 623
    • Weiss, S.J.1    Lampert, M.B.2    Test, S.T.3
  • 17
    • 0022496447 scopus 로고
    • Imbalance between polymorphonuclear leukocyte proteases and antiproteases in chronic pyogenic infections and its relation to the proteolysis of complement component C3
    • Suter, S. 1986. Imbalance between polymorphonuclear leukocyte proteases and antiproteases in chronic pyogenic infections and its relation to the proteolysis of complement component C3. Complement 3:1.
    • (1986) Complement , vol.3 , pp. 1
    • Suter, S.1
  • 19
    • 0027997410 scopus 로고
    • Role of free radicals in the pathogenesis of cystic fibrosis
    • Brown, R., and F. J. Kelly. 1994. Role of free radicals in the pathogenesis of cystic fibrosis. Thorax 49:738.
    • (1994) Thorax , vol.49 , pp. 738
    • Brown, R.1    Kelly, F.J.2
  • 21
    • 0025274624 scopus 로고
    • Acute and long-term amiloride inhalation in cystic fibrosis lung disease: A rational approach to cystic fibrosis therapy
    • App, E. M., M. King, R. Helfesrieder, D. Kohler, and H. Matthys. 1990. Acute and long-term amiloride inhalation in cystic fibrosis lung disease: a rational approach to cystic fibrosis therapy. Am. Rev. Respir. Dis. 141:605.
    • (1990) Am. Rev. Respir. Dis. , vol.141 , pp. 605
    • App, E.M.1    King, M.2    Helfesrieder, R.3    Kohler, D.4    Matthys, H.5
  • 23
    • 0020613592 scopus 로고
    • Modulation of human granulocyte and monocyte chemiluminescence responses: Evidence for distinct free radical generating systems
    • Nguyen, A. T., R. Golub, M. N. Feuillet-Fieux, and B. Descamps-Latscha. 1983. Modulation of human granulocyte and monocyte chemiluminescence responses: evidence for distinct free radical generating systems. J. Clin. Lab. Immunol. 12: 47.
    • (1983) J. Clin. Lab. Immunol. , vol.12 , pp. 47
    • Nguyen, A.T.1    Golub, R.2    Feuillet-Fieux, M.N.3    Descamps-Latscha, B.4
  • 24
    • 0023034188 scopus 로고
    • Phagocytic leukocyte oxygenation activities and chemiluminescence: A kinetic approach
    • Allen, R. C. 1986. Phagocytic leukocyte oxygenation activities and chemiluminescence: a kinetic approach. Methods Enzymol. 133:449.
    • (1986) Methods Enzymol. , vol.133 , pp. 449
    • Allen, R.C.1
  • 25
    • 0020625894 scopus 로고
    • Flow cytometry studies of oxidative products formation by neutrophils: A graded response to membrane stimulation
    • Bass, D. A., J. W. Parce, L. R. DeChatelet, P. Szejda, and M. C. Thomas. 1983. Flow cytometry studies of oxidative products formation by neutrophils: a graded response to membrane stimulation. J. Immunol. 130:1910.
    • (1983) J. Immunol. , vol.130 , pp. 1910
    • Bass, D.A.1    Parce, J.W.2    DeChatelet, L.R.3    Szejda, P.4    Thomas, M.C.5
  • 26
    • 0026582710 scopus 로고
    • Microtiter plate assay for phagocyte-derived taurine-chloramines
    • Witko, V., A. T. Nguyen, and B. Descamps-Latscha. 1992. Microtiter plate assay for phagocyte-derived taurine-chloramines. J. Clin. Lab. Anal. 6:47.
    • (1992) J. Clin. Lab. Anal. , vol.6 , pp. 47
    • Witko, V.1    Nguyen, A.T.2    Descamps-Latscha, B.3
  • 27
    • 0023807201 scopus 로고
    • Amiloride and its analogs as tool in the study of ion transport
    • Kleyman, E. J., and E. J. Cragoe, Jr. 1988. Amiloride and its analogs as tool in the study of ion transport. J. Membr. Biol. 105:1.
    • (1988) J. Membr. Biol. , vol.105 , pp. 1
    • Kleyman, E.J.1    Cragoe Jr., E.J.2
  • 28
    • 0028556251 scopus 로고
    • Migration-associated volume changes in neutrophils facilitate the migratory process in vitro
    • Rosengren, S., P. M. Henson, and G. S. Worthen. 1994. Migration-associated volume changes in neutrophils facilitate the migratory process in vitro. Am. J. Physiol. 267:C1623.
    • (1994) Am. J. Physiol. , vol.267
    • Rosengren, S.1    Henson, P.M.2    Worthen, G.S.3
  • 29
    • 0004789017 scopus 로고
    • Ion channel and carriers in leukocytes: Distribution and functional role
    • J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds. Raven Press, New York
    • Gallin, E. K., and S. Grinstein. 1992. Ion channel and carriers in leukocytes: distribution and functional role. In Inflammation: Basic Principles and Clinical Correlates. J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds. Raven Press, New York, p. 441.
    • (1992) Inflammation: Basic Principles and Clinical Correlates , pp. 441
    • Gallin, E.K.1    Grinstein, S.2
  • 30
    • 0025989243 scopus 로고
    • Selective secretion of azurophil granule contents induced by monovalent cation ionophores in human neutrophils: Evidence for direct ionophore effects on the granule membrane
    • Fittschen, C., and P. M. Henson. 1991. Selective secretion of azurophil granule contents induced by monovalent cation ionophores in human neutrophils: evidence for direct ionophore effects on the granule membrane. J. Leukocyte Biol. 50:517.
    • (1991) J. Leukocyte Biol. , vol.50 , pp. 517
    • Fittschen, C.1    Henson, P.M.2
  • 31
    • 0028521143 scopus 로고
    • Comparison of properties of membrane bound versus soluble forms of human leukocytic elastase and cathepsin
    • Bangalore, N., and J. Travis. 1994. Comparison of properties of membrane bound versus soluble forms of human leukocytic elastase and cathepsin. Biol. Chem. Hoppe-Seyler 375:659.
    • (1994) Biol. Chem. Hoppe-Seyler , vol.375 , pp. 659
    • Bangalore, N.1    Travis, J.2
  • 33
    • 0026717658 scopus 로고
    • The circulating phagocyte reflects the in vivo state of immune defense
    • Allen, R. C., and D. L. Stevens. 1992. The circulating phagocyte reflects the in vivo state of immune defense. Curr. Opin. Infect. Dis. 5:389.
    • (1992) Curr. Opin. Infect. Dis. , vol.5 , pp. 389
    • Allen, R.C.1    Stevens, D.L.2
  • 34
    • 0028135596 scopus 로고
    • Analysis of circulating phagocyte activity measured by whole blood luminescence: Correlation with clinical status
    • Stevens, D. L., A. E. Bryant, J. Huffman, K. Thompson, and R. C. Allen. 1994. Analysis of circulating phagocyte activity measured by whole blood luminescence: correlation with clinical status. J. Infect. Dis. 170:1463.
    • (1994) J. Infect. Dis. , vol.170 , pp. 1463
    • Stevens, D.L.1    Bryant, A.E.2    Huffman, J.3    Thompson, K.4    Allen, R.C.5
  • 35
    • 0026040438 scopus 로고
    • Membrane surface antigen expression on neutrophils: A reappraisal of the use of surface marker for neutrophil activation
    • Kuijpers, T. W., A. T. Tool, C. E. Van Der Schoot, L. A. Ginsel, J. J. Onderwater, D. Roos, and A. J. Verhoeven. 1991. Membrane surface antigen expression on neutrophils: a reappraisal of the use of surface marker for neutrophil activation. Blood 78:1105.
    • (1991) Blood , vol.78 , pp. 1105
    • Kuijpers, T.W.1    Tool, A.T.2    Van Der Schoot, C.E.3    Ginsel, L.A.4    Onderwater, J.J.5    Roos, D.6    Verhoeven, A.J.7
  • 36
    • 84980106819 scopus 로고
    • Anamnesis, sweat electrolyte and pulmonary function studies in parents of patients with cystic fibrosis of the pancreas
    • Orzalesi, M. M., D. Kohner, C. D. Cook, and H. Schwachman. 1963. Anamnesis, sweat electrolyte and pulmonary function studies in parents of patients with cystic fibrosis of the pancreas. Acta Paediatr. 52:267.
    • (1963) Acta Paediatr. , vol.52 , pp. 267
    • Orzalesi, M.M.1    Kohner, D.2    Cook, C.D.3    Schwachman, H.4
  • 37
    • 0023107664 scopus 로고
    • Pulmonary abnormalities in obligate heterozygotes for cystic fibrosis
    • Davies, P. B., and K. Vargo. 1987. Pulmonary abnormalities in obligate heterozygotes for cystic fibrosis. Thorax 42:120.
    • (1987) Thorax , vol.42 , pp. 120
    • Davies, P.B.1    Vargo, K.2
  • 38
    • 0029016718 scopus 로고
    • Protection against bronchial asthma by CFTR ΔF508 mutation: A heterozygote advantage in cystic fibrosis
    • Schroeder, S. A., D. M. Gaugham, and M. Swift. 1995. Protection against bronchial asthma by CFTR ΔF508 mutation: a heterozygote advantage in cystic fibrosis. Nat. Med. 1:703.
    • (1995) Nat. Med. , vol.1 , pp. 703
    • Schroeder, S.A.1    Gaugham, D.M.2    Swift, M.3
  • 39
    • 0022612677 scopus 로고
    • Increased monocyte chemiluminescence in cystic fibrosis patients and in their parents
    • Regelmann, W. E., N. M. Lunde, P. T. Porter, and P. G. Quie. 1986. Increased monocyte chemiluminescence in cystic fibrosis patients and in their parents. Pediatr. Res. 20:619.
    • (1986) Pediatr. Res. , vol.20 , pp. 619
    • Regelmann, W.E.1    Lunde, N.M.2    Porter, P.T.3    Quie, P.G.4
  • 40
    • 0024338753 scopus 로고
    • Increased phagocytic cell chemiluminescence in patients with cystic fibrosis
    • Roberts, R. L., and R. Stiehm. 1989. Increased phagocytic cell chemiluminescence in patients with cystic fibrosis. Am. J. Dis. Child 143:944.
    • (1989) Am. J. Dis. Child , vol.143 , pp. 944
    • Roberts, R.L.1    Stiehm, R.2
  • 41
    • 0020045045 scopus 로고
    • Granulocyte chemiluminescence in adolescent patients with cystic fibrosis
    • Graft, D. F., E. Mischler, P. M. Farrell, and W. Busse. 1982. Granulocyte chemiluminescence in adolescent patients with cystic fibrosis. Am. Rev. Respir. Dis. 125:540.
    • (1982) Am. Rev. Respir. Dis. , vol.125 , pp. 540
    • Graft, D.F.1    Mischler, E.2    Farrell, P.M.3    Busse, W.4
  • 42
    • 0025313752 scopus 로고
    • Increased elastase secretion by peripheral blood monocytes in cystic fibrosis patients
    • Jones, M. M., D. K. Seilheimer, G. B. Pier, and R. D. Rossen. 1990. Increased elastase secretion by peripheral blood monocytes in cystic fibrosis patients. Clin. Exp. Immunol. 80:344.
    • (1990) Clin. Exp. Immunol. , vol.80 , pp. 344
    • Jones, M.M.1    Seilheimer, D.K.2    Pier, G.B.3    Rossen, R.D.4
  • 43
    • 0029126156 scopus 로고
    • Increased degranulation of eosinophil and neutrophil granulocyles in cystic fibrosis
    • Koller, D. Y., R. Urbanek, and M. Götz. 1995. Increased degranulation of eosinophil and neutrophil granulocyles in cystic fibrosis. Am. J. Respir. Crit. Care Med 152:629.
    • (1995) Am. J. Respir. Crit. Care Med , vol.152 , pp. 629
    • Koller, D.Y.1    Urbanek, R.2    Götz, M.3
  • 44
    • 0022382209 scopus 로고
    • Intracellular pH modulates the generation of superoxide radicals by human neutrophils
    • Simchowitz, L. 1985. Intracellular pH modulates the generation of superoxide radicals by human neutrophils. J. Clin. Invest. 76:1079.
    • (1985) J. Clin. Invest. , vol.76 , pp. 1079
    • Simchowitz, L.1
  • 45
    • 0040596136 scopus 로고
    • Phorbol-ester-induced changes in cytoplasmic pH in neutrophils
    • Grinstein, S., B. Elder, and W. Furuya. 1985. Phorbol-ester-induced changes in cytoplasmic pH in neutrophils. Am. J. Physiol. 248:C379.
    • (1985) Am. J. Physiol. , vol.248
    • Grinstein, S.1    Elder, B.2    Furuya, W.3
  • 47
    • 0021203722 scopus 로고
    • Proton secretion by stimulated neutrophils: Significance of hexose monophosphate shunt activity as source of electrons and protons for the respiratory burst
    • Borregaard, N., J. H. Schwartz, and A. I. Tauber. 1984. Proton secretion by stimulated neutrophils: significance of hexose monophosphate shunt activity as source of electrons and protons for the respiratory burst. J. Clin. Invest. 74:455.
    • (1984) J. Clin. Invest. , vol.74 , pp. 455
    • Borregaard, N.1    Schwartz, J.H.2    Tauber, A.I.3
  • 48
    • 0016651257 scopus 로고
    • The role of pH in the chemiluminescent response of the myeloperoxidase-halide-HOOH antimicrobial system
    • Allen, R. C. 1975. The role of pH in the chemiluminescent response of the myeloperoxidase-halide-HOOH antimicrobial system. Biochem. Biophys. Res. Commun. 63:684.
    • (1975) Biochem. Biophys. Res. Commun. , vol.63 , pp. 684
    • Allen, R.C.1
  • 49
    • 0028566210 scopus 로고
    • Role of oxygen in phagocyte microbicidal action
    • Allen, R. C. 1994. Role of oxygen in phagocyte microbicidal action. Environ. Health Perspect. 102(Suppl. 10):201.
    • (1994) Environ. Health Perspect. , vol.102 , Issue.10 SUPPL. , pp. 201
    • Allen, R.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.