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Volumn 157, Issue 6, 1996, Pages 2712-2718

Single-Cell Analysis of IL-4 and IFN-γ Production by T Cells from HIV-Infected Individuals: Decreased IFN-γ in the Presence of Preserved IL-4 Production

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5;

EID: 0030587189     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (120)

References (51)
  • 1
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 3
    • 43949158538 scopus 로고
    • The Th1-Th2 hypothesis of HIV infection: New insights
    • Clerici, M., and G. M. Shearer. 1994. The Th1-Th2 hypothesis of HIV infection: new insights. Immunol. Today 15:575.
    • (1994) Immunol. Today , vol.15 , pp. 575
    • Clerici, M.1    Shearer, G.M.2
  • 5
    • 0026616876 scopus 로고
    • Induction of Th1 and Th2 responses: A key role for the 'natural' immune response?
    • Romagnani, S. 1992. Induction of Th1 and Th2 responses: a key role for the 'natural' immune response? Immunol. Today 13:379.
    • (1992) Immunol. Today , vol.13 , pp. 379
    • Romagnani, S.1
  • 9
    • 0023789637 scopus 로고
    • Impaired T-lymphocyte-dependent immune responses to microbial antigens in patients with HIV-1-associated persistent generalized lymphadenopathy
    • Ballet, J. J., L. J. Couderc, C. Rabian-Herzog, C. Duval-Roy, M. Janier, F. Danon, J. P. Clauvel, and M. Seligmann. 1988. Impaired T-lymphocyte-dependent immune responses to microbial antigens in patients with HIV-1-associated persistent generalized lymphadenopathy. AIDS 2:291.
    • (1988) AIDS , vol.2 , pp. 291
    • Ballet, J.J.1    Couderc, L.J.2    Rabian-Herzog, C.3    Duval-Roy, C.4    Janier, M.5    Danon, F.6    Clauvel, J.P.7    Seligmann, M.8
  • 12
    • 0023683969 scopus 로고
    • + cell production of interferon gamma and the clinical spectrum of patients at risk for and with acquired immunodeficiency syndrome
    • + cell production of interferon gamma and the clinical spectrum of patients at risk for and with acquired immunodeficiency syndrome. Arch. Intern. Med. 148:1613.
    • (1988) Arch. Intern. Med. , vol.148 , pp. 1613
    • Murray, H.W.1    Scavuzzo, D.A.2    Kelly, C.D.3    Rubin, B.Y.4    Roberts, R.B.5
  • 15
    • 0027340164 scopus 로고
    • A Th1→Th2 switch is a critical step in the etiology of HIV infection
    • Clerici, M., and G. M. Shearer. 1993. A Th1→Th2 switch is a critical step in the etiology of HIV infection. Immunol. Today 14:107.
    • (1993) Immunol. Today , vol.14 , pp. 107
    • Clerici, M.1    Shearer, G.M.2
  • 19
    • 0027332299 scopus 로고
    • Elevated IFN-γ and decreased IL-2 gene expression are associated with HIV infection
    • Fan, J., H. Z. Bass, and J. L. Fahey. 1993. Elevated IFN-γ and decreased IL-2 gene expression are associated with HIV infection. J. Immunol. 151:5031.
    • (1993) J. Immunol. , vol.151 , pp. 5031
    • Fan, J.1    Bass, H.Z.2    Fahey, J.L.3
  • 20
    • 0027526657 scopus 로고
    • Changes in interleukin-2 and interleukin-4 production in asymptomatic human immunodeficiency virus-seropositive individuals
    • Clerici, M., F. T. Hakim, D. J. Venzon, S. Blatt, C. W. Hendrix, T. A. Wynn, and G. M. Shearer. 1993. Changes in interleukin-2 and interleukin-4 production in asymptomatic human immunodeficiency virus-seropositive individuals. J. Clin. Invest. 91:759.
    • (1993) J. Clin. Invest. , vol.91 , pp. 759
    • Clerici, M.1    Hakim, F.T.2    Venzon, D.J.3    Blatt, S.4    Hendrix, C.W.5    Wynn, T.A.6    Shearer, G.M.7
  • 21
    • 0028232637 scopus 로고
    • Th1 and Th2 cytokine production by peripheral blood mononuclear cells from HIV-infecled patienls
    • Barcellini, W., G. P. Rizzardi, M. O. Borghi, C. Fain, A. Lazzarin, and P. L. Meroni. 1994. Th1 and Th2 cytokine production by peripheral blood mononuclear cells from HIV-infecled patienls. AIDS 8:757.
    • (1994) AIDS , vol.8 , pp. 757
    • Barcellini, W.1    Rizzardi, G.P.2    Borghi, M.O.3    Fain, C.4    Lazzarin, A.5    Meroni, P.L.6
  • 22
    • 0028135425 scopus 로고
    • T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection
    • Zhang, M., J. Gong, D. V. Iyer, B. E. Jones, R. L. Modlin, and P. F. Barnes. 1994. T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection. J. Clin. Invest. 94:2435.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2435
    • Zhang, M.1    Gong, J.2    Iyer, D.V.3    Jones, B.E.4    Modlin, R.L.5    Barnes, P.F.6
  • 23
    • 0029143848 scopus 로고
    • HIV infection suppresses type 1 lymphokine and IL-12 responses to Toxoplasma gondii but fails to inhibit the synthesis of other parasite-induced monokines
    • Gazzinelli, R. T., S. Bala, R. Stevens, M. Baseler, L. Wahl, J. Kovacs, and A. Sher. 1995. HIV infection suppresses type 1 lymphokine and IL-12 responses to Toxoplasma gondii but fails to inhibit the synthesis of other parasite-induced monokines. J. Immunol. 155:1565.
    • (1995) J. Immunol. , vol.155 , pp. 1565
    • Gazzinelli, R.T.1    Bala, S.2    Stevens, R.3    Baseler, M.4    Wahl, L.5    Kovacs, J.6    Sher, A.7
  • 25
    • 0028275847 scopus 로고
    • Increased levels of interferon-gamma (JFN-gamma), IL-4 and transforming growth factor-β (TGF-β) mRNA expressing blood mononuclear cells in human HIV infection
    • Navikas, V., J. Link, B. Wahren, C. Persson, and H. Link. 1994. Increased levels of interferon-gamma (JFN-gamma), IL-4 and transforming growth factor-β (TGF-β) mRNA expressing blood mononuclear cells in human HIV infection. Clin. Exp. Immunol. 96:59.
    • (1994) Clin. Exp. Immunol. , vol.96 , pp. 59
    • Navikas, V.1    Link, J.2    Wahren, B.3    Persson, C.4    Link, H.5
  • 26
    • 0025057550 scopus 로고
    • HIV infection of H9 lymphoblastoid cells chronically activates the inositol polyphosphate pathway
    • Nye, K. E., K. A. Knox, and A. J. Pinching. 1990. HIV infection of H9 lymphoblastoid cells chronically activates the inositol polyphosphate pathway. AIDS 4:41.
    • (1990) AIDS , vol.4 , pp. 41
    • Nye, K.E.1    Knox, K.A.2    Pinching, A.J.3
  • 27
    • 0028168941 scopus 로고
    • Cytokines from lymphoid organs of HIV-infected patients: Production and role in the immune disequilibrium of the disease and in the development of B lymphomas
    • Emilie, D., R. Fior, L. Llorente, A. Marfaing-Koka, M. Peuchmaur, O. Devergne, B. Jarousse, J. Wijdenes, F. Boue, and P. Galanaud. 1994. Cytokines from lymphoid organs of HIV-infected patients: production and role in the immune disequilibrium of the disease and in the development of B lymphomas. Immunol. Rev. 140:5.
    • (1994) Immunol. Rev. , vol.140 , pp. 5
    • Emilie, D.1    Fior, R.2    Llorente, L.3    Marfaing-Koka, A.4    Peuchmaur, M.5    Devergne, O.6    Jarousse, B.7    Wijdenes, J.8    Boue, F.9    Galanaud, P.10
  • 29
    • 0028884903 scopus 로고
    • Expression of IL-10, IL-4 and interferon-gamma in unstimulated and mitogen-stimulated peripheral blood lymphocytes from HIV-seropositive patients
    • Diaz-Mitoma, F., A. Kumar, S. Karimi, M. Kryworuchko, M. P. Daftarian, W. D. Creery, L. G. Filion, and W. Cameron. 1995. Expression of IL-10, IL-4 and interferon-gamma in unstimulated and mitogen-stimulated peripheral blood lymphocytes from HIV-seropositive patients. Clin. Exp. Immunol. 102:31.
    • (1995) Clin. Exp. Immunol. , vol.102 , pp. 31
    • Diaz-Mitoma, F.1    Kumar, A.2    Karimi, S.3    Kryworuchko, M.4    Daftarian, M.P.5    Creery, W.D.6    Filion, L.G.7    Cameron, W.8
  • 32
    • 0025855437 scopus 로고
    • Altered production of tumour necrosis factors alpha and beta and interferon gamma by HIV-infected individuals
    • Vyakarnam, A., P. Matear, A. Meager, G. Kelly, B. Stanley, I. Weller, and P. Beverley. 1991. Altered production of tumour necrosis factors alpha and beta and interferon gamma by HIV-infected individuals. Clin. Exp. Immunol. 84:109.
    • (1991) Clin. Exp. Immunol. , vol.84 , pp. 109
    • Vyakarnam, A.1    Matear, P.2    Meager, A.3    Kelly, G.4    Stanley, B.5    Weller, I.6    Beverley, P.7
  • 34
    • 0028267888 scopus 로고
    • Role of interleukin-10 (IL-10) in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus (HIV-1)
    • Clerici, M., T. A. Wynn, J. A. Berzofsky, S. P. Blatt, C. W. Hendrix, A. Sher, R. L. Coffman, and G. M. Shearer. 1994. Role of interleukin-10 (IL-10) in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus (HIV-1). J. Clin. Invest. 93:768.
    • (1994) J. Clin. Invest. , vol.93 , pp. 768
    • Clerici, M.1    Wynn, T.A.2    Berzofsky, J.A.3    Blatt, S.P.4    Hendrix, C.W.5    Sher, A.6    Coffman, R.L.7    Shearer, G.M.8
  • 35
    • 0028670686 scopus 로고
    • Dysregulation of interleukin 8, interleukin 10, and interleukin 12 release by alveolar macrophages from HIV type 1-infected subjects
    • Denis, M., and E. Ghadirian. 1994. Dysregulation of interleukin 8, interleukin 10, and interleukin 12 release by alveolar macrophages from HIV type 1-infected subjects. AIDS Res. Hum. Relroviruses 10:1619.
    • (1994) AIDS Res. Hum. Relroviruses , vol.10 , pp. 1619
    • Denis, M.1    Ghadirian, E.2
  • 38
    • 0018174365 scopus 로고
    • T cell growth factor: Parameters of production and a quantitative microassay for activity
    • Gillis, S., M. M. Ferm, W. Ou, and K. A. Smith. 1978. T cell growth factor: parameters of production and a quantitative microassay for activity. J. Immunol. 120:2027.
    • (1978) J. Immunol. , vol.120 , pp. 2027
    • Gillis, S.1    Ferm, M.M.2    Ou, W.3    Smith, K.A.4
  • 39
    • 0026509257 scopus 로고
    • Interleukin (IL)-4 production by human T cells: Differential regulation of IL-4 vs. IL-2 production
    • Van der Pouw Kraan, T. C. T. M., C. Van Kooten, I. Rensink, and L. Aarden. 1992. Interleukin (IL)-4 production by human T cells: differential regulation of IL-4 vs. IL-2 production. Eur. J. Immunol. 22:1237.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1237
    • Van Der Pouw Kraan, T.C.T.M.1    Van Kooten, C.2    Rensink, I.3    Aarden, L.4
  • 41
    • 0026611676 scopus 로고
    • Strategies and practice of anti-cytokine monoclonal antibody development: Immunoassay of IL-10 and IL-5 in clinical samples
    • Abrams, J. S., M. G. Roncarolo, H. Yssel, U. Andersson, G. J. Gleich, and J. Silver. 1992. Strategies and practice of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol. Rev. 127:5.
    • (1992) Immunol. Rev. , vol.127 , pp. 5
    • Abrams, J.S.1    Roncarolo, M.G.2    Yssel, H.3    Andersson, U.4    Gleich, G.J.5    Silver, J.6
  • 43
    • 0019953155 scopus 로고
    • Tumor-promoting phorbol esters selectively abrogate the expression of the T4 differentiation antigen expressed on normal and malignant (Sézary) T helper lymphocytes
    • Solbach, W. 1982. Tumor-promoting phorbol esters selectively abrogate the expression of the T4 differentiation antigen expressed on normal and malignant (Sézary) T helper lymphocytes. J. Exp. Med. 156:1250.
    • (1982) J. Exp. Med. , vol.156 , pp. 1250
    • Solbach, W.1
  • 45
    • 0020635123 scopus 로고
    • Perturbation of vesicular traffic with the carboxylic ionophore monensin
    • Tartakoff, A. M. 1983. Perturbation of vesicular traffic with the carboxylic ionophore monensin. Celt 32:1025.
    • (1983) Celt , vol.32 , pp. 1025
    • Tartakoff, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.