The Mechanisms of Peptide Exchange and β2-Microglobulin Exchange on Cell Surface Ld and Kb Molecules Are Noncooperative

Journal of Immunology

Volumn 157, Issue 6, 1996, Pages 2256-2261

  Cook, James R ^a   Myers, Nancy B ^a   Hansen, Ted H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; H 2KB PROTEIN, MOUSE; H-2KB PROTEIN, MOUSE; H2 ANTIGEN; HISTOCOMPATIBILITY ANTIGEN H 2D(B); HISTOCOMPATIBILITY ANTIGEN H-2D(B); MEMBRANE PROTEIN; PEPTIDE;

ANIMAL; ARTICLE; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; L CELL; METABOLISM; MOUSE; PROTEIN BINDING;

ANIMALS; BETA 2-MICROGLOBULIN; CELL DIVISION; H-2 ANTIGENS; L CELLS (CELL LINE); MEMBRANE PROTEINS; MICE; PEPTIDES; PROTEIN BINDING;

EID: 0030587120     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Bjorkman, P. J., and P. Parham. 1990. Structure, function, and diversity of class I major histocompatibility complex molecules. Annu. Rev. Biochem. 59:253.
2. Germain, R. N., and D. H. Margulies. 1993. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11:403.
3. Germain, R. N. 1994. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 76:287.
4. Ciechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79: 13.
5. Townsend, A., C. Ohlen, J. Bastin, H.-G. Ljunggren, L. Foster, and K. Karre. 1989. Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 340:443.
6. d class I MHC molecule. Nature 344:439.
7. b class I major histocompatibility complex binding of an exogenous influenza peptide. Proc. Natl. Acad. Sci. USA 88:301.
8. 2-microglobulin promoting functional peptide association with purified soluble class I MHC molecules. Nature 349:74.
9. 2-microglobulin in peptide binding by class I molecules. Science 250:1423.
10. 2-microglobulin is required for antigenic peptide binding to isolated class I major histocompatibility complex molecules. Eur. J. Immunol 21:2289.
11. b class I major histocompatibility complex binding of exogenous peptides. Proc. Natl. Acad. Sci. USA 87:7517.
12. 2m in vivo. Immunogentics. In press.
13. d, and two genes reported to encode tumor-specific antigens. J. Exp. Med. 168: 1719.
14. d antigen, the product of a third polymorphic locus of the major histocompatibility complex. J. Immunol. 125:2473.
15. Oi, V. T., P. P. Jones, J. W. Goding, and L. A. Herzenberg. 1978. Properties of monoclonal antibodies to mouse Ig allotypes, H-2, and Ia antigens. Curr. Top. Microbiol. Immunol. 81:115.
16. Allen, H., D. Wraith, P. Pala, B. Askonas, and R. A. Flavell. 1984. Domain interactions of H-2 class I antigens alter cytotoxic T-cell recognition sites. Nature 309:279.
17. d class I major histocompatibility molecules determines their antigenic structure. J. Exp. Med. 173:449.
18. Reddehase, M. J., J. B. Rothbard, and U. H. Koszinowski. 1989. A pentapeptide as minimal antigenic determinant for MHC class I restricted T lymphocytes. Nature 337:651.
19. + T cell clone. Cell 69:989.
20. ds: sequence motif, quantitative binding, and molecular modeling of the complex. J. Exp. Med. 176:1681.
21. McReynolds, L., B. W. O'Malley, A. D. Nisbet, J. E. Fothergill, D. Givol, S. Fields, M. Ropertson, and G. G. Brownlee. 1978. Sequence of chicken ovalbumin mRNA. Nature 273:723.
22. Merrifield, R. B. 1963. Solid phase peptide synthesis. I. The synthesis of a tetrapeptide. J. Am. Chem. Soc. 85:2149.
23. Gorka, J., D. W. McCourt, and B. D. Schwartz. 1989. Automated synthesis of a C-terminal photoprobe using combined Fmoc and t-Boc synthesis strategies on a single automated peptide synthesizer. Pept. Res. 2:376.
24. Coligan, J. E., A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. 1991. Current Protocols in Immunology. Greene Publishing Associates and Wiley Interscience, New York.
25. b at the cell surface. J. Immunol. 153:5068.
26. 2-microglobulin. Proc. Natl. Acad. Sci. USA 89:7767.
27. Kageyama, S., T. J. Tsomides, Y. Sykulev, and H. N. Eisen. 1995. Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J. Immunol. 154:567.
28. Pfiefer, J. D., M. J. Wick, R. L. Roberts, K. Findlay, S. J. Normark, and C. V. Harding. 1993. Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature 361:359.
29. Day, P. M., F. Esquivel, J. Lukszo, J. R. Bennik, and J. W. Yewdell. 1995. Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules. Immunity 2:137.
30. 2-microglobulin dissociation rate is an accurate indicator of the stability of MHC class I heterodimers and depends on which peptide is bound. J. Immunol. 149:1896.
31. d molecules at the cell surface. J. Exp. Med 178:2035.
32. 2-microglobulin. J. Exp. Med. 160:317.
33. 2-microglobulin-deficient mice. J. Immunol. 154:47.