Mutations in both the U5 region and the primer-binding site influence the selection of the tRNA used for the initiation of HIV-1 reverse transcription

Virology

Volumn 222, Issue 2, 1996, Pages 401-414

  Kang, Sang Moo ^a   Wakefield, John K ^a   Morrow, Casey D ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRIMER RNA; RNA DIRECTED DNA POLYMERASE; TRANSFER RNA;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; VIRUS INFECTIVITY; VIRUS MUTATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EID: 0030586782     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0437     Document Type: Article

References (40)

1. Aiyar, A., Ge, Z., and Leis, J. (1994). A specific orientation of RNA secondary structure is required for initiation of reverse transcription. J. Virol. 68, 611-618.
2. Baltimore, D. (1970). Viral RNA-dependent DNA polymerase. Nature (London) 226, 1209-1211.
3. Lys,3 with nucleocapsid protein and reverse transcriptase. J. Mol. Biol. 231, 185-190.
4. Barat, C. V. L., Schatz, O., Keith, G., Nugeyre, M. T., Gruninger-Leitch, F., Barre-Sinoussi, F., LeGrice, S. F. J., and Darlix, J. L. (1989). HIV-1 reverse transcriptase specifically interacts with the anticodon domain of its cognate primer tRNA. EMBO J. 8, 3279-3285.
5. Chapman, K. B., Bystrom, A. S., and Boeke, J. D. (1992). Initiator methionine tRNA is essential for Ty 1 transposition in yeast. Proc. Natl. Acad. Sci. USA 89, 3236-3240.
6. Colicelli, J., and Goff, S. P. (1987). Isolation of a recombinant murine leukemia virus utilizing a new primer tRNA. J. Virol. 57, 37-45.
7. Lys,3 J. Virol. 69, 3090-2097.
8. Delahunty, M. D., Wilson, S. H., and Karpel, R. L. (1994). Studies on primer binding of HIV-1 reverse transcription using a fluorescent probe. J. Mol. Biol. 236, 469-479.
9. Gilboa, E., Mitra, S. W., Goff, S., and Baltimore, D. (1979). A detailed model of reverse transcription and tests of crucial aspects. Cell 18, 93-100.
10. Harada, F., Matsubara, M., and Kato, N. (1984). Stable tRNA precursors in Hela cells. Nucleic Acids Res. 12, 9263-9269.
11. Harada, F., Peters, G., and Dahlberg, J. (1979). The primer tRNA for Moloney murine leukemia virus DNA synthesis. J. Biol. Chem. 254, 10979-10985.
12. Harada, F., Sawyer, R., and Dahlberg, J. (1975). A primer ribonucleic acid for initiation of in vitro Rous sarcoma virus deoxyribonucleic acid synthesis. J. Biol. Chem. 250, 3487-3497.
13. Hu, W.-S., and Temin, H. M. (1990). Retroviral recombination and reverse transcription. Science 250, 1227-1233.
14. Lys,3 (template/primer) complex. J. Mol. Biol. 247, 236-250.
15. Lys,3. EMBO J. 15, 917-924.
16. Jang, M., Mak, J., Ladha, A., Cohen, E., Klein, M., Rovinski, B., and Kleiman, L. (1993). Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1. J. Virol. 67, 3246-3253.
17. Kikuchi, Y., Ando, Y., and Shiba, T. (1986). Unusual priming mechanism of RNA-directed DNA synthesis in copia retrovirus-like particles in Drosophila. Nature (London) 323, 824-826.
18. Kleiman, L., Caundry, S., Boulerice, F., Wainberg, M. A., and Parniak, M. A. (1991). Incorporation of tRNAs into normal and mutant HIV-1. Biochem. Bophys. Res. Commun. 174, 1272-1280.
19. Gln,2 as a primer in an in vitro primer-utilization assay. Proc. Natl. Acad. Sci. USA 89, 9652-9656.
20. Li, X., Johnson, M., Arts, E. J., Gu, Z., Kleiman, L., Wainberg, M. A., and Parniak, M. A. (1994). Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication. J. Virol. 68, 6198-6206.
21. Lys into human immunodeficiency virus type 1 particles. J. Virol. 68, 2065-2072.
22. Maniatis, T., Fritsch, E. F., and Sambrook, J. (1982). "Molecular Cloning: A Laboratory Manual." Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
23. Marquet, R., Isel, C., Ehreshmann, C., and Ehreshmann, B. (1995). tRNA as primer of reverse transcriptase. Biochimie 77, 113-124.
24. Lys,3, in vitro, is essentially not specific. J. Biol. Chem. 270, 1650-1656.
25. Peters, G., and Dahlberg, J. E. (1979). RNA-directed DNA synthesis in the Moloney murine leukemia virus: Interaction between the primer tRNA and the genome. J. Virol. 31, 398-407.
26. Peters, G., and Glover, C. (1980). tRNAs and primer of RNA-directed DNA synthesis in mouse mammary tumor virus. J. Virol. 35, 31-40.
27. Ratner, L., Fisher, A., Linda, L., Agodzinski, J., Mitsuya, H., Liou, R.-S., Gallo, R. C., and Wong-Staal, F. (1987). Complete nucleotide sequences of functional clones of the AIDS virus. AIDS Res. Hum. Retroviruses 3, 57-69.
28. Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Jasephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., Ivanoff, L. S. R., Petteway, J., Pearson, M. L., Lautenberge, J. A., Papas, T. S., Ghrayeb, J., Chang, N. T., Gallo, R. C., and Wong-Staal, F. (1985). Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature (London) 313, 277-284.
29. Lys primer binding site of human immunodeficiency virus type 1 identify essential regions for reverse transcription. J. Virol. 65, 4555-4564.
30. Lys induce important structural changes in human immunodeficiency virus reverse transcriptase. FEBS Lett. 277, 239-242.
31. Sanger, F., Nicklen, S., and Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
32. Lys as evidenced by footprinting studies and inhibition with synthetic oligoribonucleotides. J. Mol. Biol. 226, 1-6.
33. Sprintzl, M., Hartmann, T., Weber, J., Blank, J., and Zeidler, R. (1989). Compilation of tRNA sequences and sequences of tRNA genes. Nucleic Acids Res. 17(Suppl.), r1-r172.
34. Taylor, J. M. (1977). An analysis of the role of tRNA species as primers for transcription into DNA of RNA tumor virus genomes. Biochem. Biophys. Acta 473, 57-71.
35. Taylor, J. M., and Hsu, T. W. (1980). Reverse transcription of avian sarcoma virus RNA into DNA might involve copying of the tRNA primer. J. Virol. 33, 531-534.
36. Temin, H. M., and Mizutani, S. (1970). RNA-directed DNA polymerase in virions of Rous sarcoma virus. Nature 226, 1211-1213.
37. Vicenzi, E. D., Dimitro, S., Engleman, A., Migone, T., Purcell, D. F. J., Leonard, J., Englund, G., and Martin, M. A. (1994). An integration-defective U5 deletion mutant of human immunodeficiency virus type 1 reverts by eliminating additional long terminal repeat sequences. J. Virol. 68, 7879-7890.
38. His. J. Virol. 70, 966-975.
39. Wakefield, J. K., Rhim, H., and Morrow, C. D. (1994). Minimal sequence requirements of a functional human immunodeficiency virus type 1 primer binding site. J. Virol. 68, 1605-1614.
40. Lys,3. J. Virol. 69, 6021-6029.