Tyrphostin A9 Inhibits Calcium Release-Dependent Phosphorylations and Calcium Entry Via Calcium Release-Activated Channel in Jurkat T Cells

Journal of Immunology

Volumn 157, Issue 4, 1996, Pages 1468-1473

  Marhaba, Rachid ^a   Mary, Florence ^a   Pelassy, Claudette ^a   Stanescu, Alexandra Teodor ^b   Aussel, Claude ^a   Breittmayer, Jean Philippe ^a  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

^b VICTOR BABES NATIONAL INSTITUTE OF PATHOLOGY   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL; ENZYME INHIBITOR; GENISTEIN; IONOMYCIN; IONOPHORE; ISOFLAVONE DERIVATIVE; LAVENDUSTIN A; OKT 3; PHENOL DERIVATIVE; PHOSPHATIDYLSERINE; PHOSPHOTYROSINE; TERPENE; THAPSIGARGIN; TUMOR PROTEIN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CHEMICAL PHENOMENA; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR SPACE; HUMAN; INTRACELLULAR FLUID; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; T CELL LEUKEMIA;

CALCIUM; CALCIUM CHANNELS; DEPRESSION, CHEMICAL; ENZYME INHIBITORS; EXTRACELLULAR SPACE; GENISTEIN; HUMANS; INTRACELLULAR FLUID; IONOMYCIN; IONOPHORES; ISOFLAVONES; LEUKEMIA, T-CELL, ACUTE; MUROMONAB-CD3; NEOPLASM PROTEINS; PHENOLS; PHOSPHATIDYLSERINES; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; TERPENES; THAPSIGARGIN; TUMOR CELLS, CULTURED;

EID: 0030586619     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. 2+ and release from internal stores in activated human T lymphocytes. Eur. J. Immunol. 20:1237.
2. Hahn, W. C., S. J. Burakoff, and B. E. Bierer. 1993. Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. J. Immunol. 150:2607.
3. 2+ mobilization. Biochem. J. 247:695.
4. Ledbetter, J. A., C. H. June, L. S. Grosmaire, and P. S. Rabinovitch. 1987. Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes. Proc. Natl. Acad. Sci. USA 84:1384.
5. Sarkadi, B., A. Tordai, L. Homolya, O. Scharff, and G. Gardos. 1991. Calcium influx and intracellular calcium release in anti-CD3 antibody-stimulated and thapsigargin-treated human T lymphoblasts. J. Membr. Biol. 123:9.
6. 2+ and membrane potential in lymphocytes. Nature 295:68.
7. Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
8. Berridge, M. J. 1993. Inositol triphosphate and calcium signalling. Nature 361: 315.
9. Kanner, S. B., J. P. Deans, and J. A. Ledbetter. 1992. Regulation of CD3-induced phospholipase C-γ1 (PLCγ1) tyrosine phosphorylation by CD4 and CD45 receptors. Immunology 75:441.
10. King, S., G. Whitley, M. Salmon, and A. Johnstone. 1989. Phosphoinositide hydrolysis in mitogen-stimulated human peripheral-blood T lymphocytes. Biochem. J. 262:747.
11. Kuno, M., J. Goronzy, C. M. Weyand, and P. Gardner. 1986. Single-channel and whole cell recordings of mitogen-regulated inward currents in human cloned helper T lymphocytes. Nature 323:269.
12. Kuno, M., and P. Gardner. 1987. Ion channels activated by inositol 1,4,5-triphosphate in plasma membrane of human T-lymphocytes. Nature 326:301.
13. 2+ required for T cell activation. J. Immunol. 149:1912.
14. Ng, J., B. B. Fredholm, M. Jondal, and T. Anderson. 1988. Regulation of receptor-mediated calcium influx across the plasma membrane in a human leukemic T-cell line: evidence of its dependence on an initial calcium mobilization from intracellular stores. Biochim. Biophys. Acta 971:207.
15. Chandy, K. G., T. E. DeCoursey, M. D. Cahalan, and S. Gupta. 1985. Electroimmunology: the physiologic role of ion channels in the immune system. J. Immunol. 135:787.
16. Putney, J. W. J. 1990. Capacitative calcium entry revisited. Cell Calcium 11:611.
17. Hoth, M., and R. Penner. 1992. Depletion of intracellular calcium stores activates a calcium current in most cells. Nature 355:353.
18. 2+ stores: kinetics evidence for short-lived mediators. Biochem. J. 288:519.
19. 2+-ATPase inhibitors induce interleukin-2 synthesis and T-cell proliferation. Cell. Immunol. 149:248.
20. Breittmayer, J. P., P. Berthe, J. L. Cousin, A. Bernard, and C. Aussel. 1993. CD3 monoclonal antibodies evoke the same cytochrome P450-regulated capacitative entry of calcium as thapsigargin in Jurkat cells. Cell. Immunol. 152:143.
21. 2+ influx. Nature 364: 809.
22. 2+. J. Biol. Chem. 270:29.
23. Thomas, D., and M. R. Hanley. 1995. Evaluation of calcium influx factors from stimulated Jurkat T lymphocytes by microinjection into Xenopus oocytes. J. Biol. Chem. 270:6429.
24. Hardie, R. C., A. Peretz, A. Rom-Glas, S. A. Bishop, Z. Selinger, and B. Minke. 1993. Protein kinase C is required for light adaptation in Drosophila photoreceptors. Nature 363:634.
25. 2+ entry pathway in human neutrophils. J. Biol. Chem. 268:13055.
26. + current by means of a phosphatase and a diffusible messenger. Nature 364:814.
27. 2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura2-loaded human platelets. J. Biol. Chem. 268:18151.
28. 2+ influx by a tyrosine kinase-dependent pathway. J. Biol. Chem. 269:26239.
29. Vostal, J. G., W. L. Jackson, and N. R. Shulman. 1991. Cytosolic and stored calcium antagonistically control tyrosine phosphorylation of specific platelet proteins. J. Biol. Chem. 266:16911.
30. Owen, C. S. 1993. Simultaneous measurements of two cations with the fluorescent dye Indo-1. Anal. Biochem. 215:90.
31. 2+ stores in Jurkat T-cells. Biochem. J. 288:785.
32. 2+ stores. Biochem. J. 274:193.
33. 2+ stores. Proc. Natl. Acad. Sci. USA 90:6295.
34. 2+-ATPase inhibitors. J. Immunol. 152:5226.
35. 2+ entry in fura-2-loaded human platelets. Biochem. J. 303:337.
36. 2+ entry by tyrosine kinase inhibitors. J. Biol. Chem. 268:9945.
37. Levitzki, A., and C. Gilon. 1991. Tyrphostins are molecular tools and potential antiproliferative drugs. Trends Pharmacol. Sci. 12:171.
38. Trevillyan, J. M., Y. Lu, D. Atluru, C. A. Phillips, and J. M. Bjorndahl. 1990. Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase. J. Immunol. 145:3223.
39. Parekh, A. B., and R. Penner. 1995. Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells. Proc. Natl. Acad. Sci. USA 92:7907.
40. 3+ concentrations block the calcium release activated channel, and impair CD69 and CD25 expression in CD3- or thapsigargin-activated Jurkat cells. Biochem. J. 313:909.
41. O'Dell, T. J., E. R. Kandel, and S. G. N. Grant. 1991. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature 353:558.