Physical factors affecting the storage stability of freeze-dried interleukin-1 receptor antagonist: Glass transition and protein conformation

Archives of Biochemistry and Biophysics

Volumn 331, Issue 2, 1996, Pages 249-258

  Chang, Byeong S ^a   Beauvais, Robert M ^b   Dong, Aichun ^b,c   Carpenter, John F ^b  

^a AMGEN INC   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF NORTHERN COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SODIUM; GLASS; GLYCINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MANNITOL; SODIUM DIHYDROGEN PHOSPHATE; SORBITOL; SUCROSE; TREHALOSE;

ARTICLE; DRUG FORMULATION; FREEZE DRYING; IMMUNOPHARMACOLOGY; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STABILITY; PROTEIN STRUCTURE;

EID: 0030586287     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0305     Document Type: Article

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