Synthesis of octalactin lactone and side chain

Tetrahedron Letters

Volumn 37, Issue 29, 1996, Pages 5049-5052

  Andrus, Merritt B ^a   Argade, Ankush B ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORONIC ACID DERIVATIVE; CYTOTOXIC AGENT; HYDROXYACID; LACTONE; NATURAL PRODUCT; OCTALACTIN A; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SEQUENCE; ARTICLE; DRUG SYNTHESIS; GAS CHROMATOGRAPHY; OXIDATION;

EID: 0030586203     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01014-3     Document Type: Article

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23. 5.
24. 19. The substrates were synthesized following a modified route starting with 1,7-heptane diol, similar in manner to hydroxy acid 3 shown in figure 1.
25. 20. No ion was observed in the Mx2 region of the mass spectrum.
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28. 2ZrHCl was prepared according to: Buchwald, S. L.; LaMaire, S. J.; Nielsen, R. B.; Watson, B. T.; King, M. Tetrahedron Lett. 1987, 28, 3895.