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Volumn 221, Issue 2, 1996, Pages 281-290

A dominant mutant form of the herpes simplex virus ICP8 protein decreases viral late gene transcription

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; DNA REPLICATION; DNA SYNTHESIS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; VERO CELL; VIRUS EXPRESSION; VIRUS GENE; VIRUS MUTANT; VIRUS TRANSCRIPTION;

EID: 0030586049     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0377     Document Type: Article
Times cited : (20)

References (42)
  • 1
    • 0026033993 scopus 로고
    • Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DMA-binding protein
    • Bush, M., Yager, D. R., Gao, M., Weisshart, K., Marcy, A. I., Coen, D. M., and Knipe, D. M. (1991). Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DMA-binding protein. J. Virol. 65, 1082-1089.
    • (1991) J. Virol. , vol.65 , pp. 1082-1089
    • Bush, M.1    Yager, D.R.2    Gao, M.3    Weisshart, K.4    Marcy, A.I.5    Coen, D.M.6    Knipe, D.M.7
  • 2
    • 0022919477 scopus 로고
    • A method for identifying the viral genes required for herpesvirus DNA replication
    • Challberg, M. D. (1986). A method for identifying the viral genes required for herpesvirus DNA replication. Proc. Natl. Acad. Sci. USA 83, 9094-9098.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9094-9098
    • Challberg, M.D.1
  • 3
    • 0026659850 scopus 로고
    • Transactivation of the major capsid protein gene of herpes simplex virus type 1 requires a cellular transcription factor
    • Chen, S., Mills, L., Perry, P., Riddle, S., Wobig, R., Lown, R., and Millette, R. L. (1992). Transactivation of the major capsid protein gene of herpes simplex virus type 1 requires a cellular transcription factor. J Virol. 66, 4304-4314.
    • (1992) J Virol. , vol.66 , pp. 4304-4314
    • Chen, S.1    Mills, L.2    Perry, P.3    Riddle, S.4    Wobig, R.5    Lown, R.6    Millette, R.L.7
  • 4
    • 0019365343 scopus 로고
    • Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides
    • Conley, A. J., Knipe, D. M., Jones, P. C., and Roizman, B. (1981). Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides. J. Virol. 37, 191-206.
    • (1981) J. Virol. , vol.37 , pp. 191-206
    • Conley, A.J.1    Knipe, D.M.2    Jones, P.C.3    Roizman, B.4
  • 5
    • 0024276563 scopus 로고
    • Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein
    • de Bruyn Kops, A., and Knipe, D.M. (1988). Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein. Cell 55, 857-868.
    • (1988) Cell , vol.55 , pp. 857-868
    • De Bruyn Kops, A.1    Knipe, D.M.2
  • 6
    • 0021797441 scopus 로고
    • Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4
    • DeLuca, N. A., and Schaffer, P. A. (1985). Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4. Mol. Cell. Biol. 5, 1997-1208.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 1997-11208
    • DeLuca, N.A.1    Schaffer, P.A.2
  • 7
    • 0018098976 scopus 로고
    • On the association of virus proteins with the nuclei of cells infected with herpes simplex virus
    • Fenwick, M. L., Walker, M. J., and Petkevich, J. M. (1978). On the association of virus proteins with the nuclei of cells infected with herpes simplex virus. J. Gen. Virol. 39, 519-529.
    • (1978) J. Gen. Virol. , vol.39 , pp. 519-529
    • Fenwick, M.L.1    Walker, M.J.2    Petkevich, J.M.3
  • 9
    • 0023938191 scopus 로고
    • Genetic identification of a portion of the herpes simplex virus ICP8 protein required for DNA-binding
    • Gao, M., Bouchey, J., Curtin, K., and Knipe, D. M. (1988). Genetic identification of a portion of the herpes simplex virus ICP8 protein required for DNA-binding. Virology 163, 319-329.
    • (1988) Virology , vol.163 , pp. 319-329
    • Gao, M.1    Bouchey, J.2    Curtin, K.3    Knipe, D.M.4
  • 10
    • 0024427401 scopus 로고
    • Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein
    • Gao, M., and Knipe, D. M. (1989). Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein. J. Virol. 63, 5258-5267.
    • (1989) J. Virol. , vol.63 , pp. 5258-5267
    • Gao, M.1    Knipe, D.M.2
  • 11
    • 0025812949 scopus 로고
    • Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression
    • Gao, M., and Knipe, D. M. (1991). Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression. J. Virol. 65, 2666-2675.
    • (1991) J. Virol. , vol.65 , pp. 2666-2675
    • Gao, M.1    Knipe, D.M.2
  • 12
    • 0020571019 scopus 로고
    • Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression
    • Godowski, P. J., and Knipe, D. M. (1983). Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression. J. Virol. 47, 478-486.
    • (1983) J. Virol. , vol.47 , pp. 478-486
    • Godowski, P.J.1    Knipe, D.M.2
  • 13
    • 0022343688 scopus 로고
    • Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes
    • Godowski, P. J., and Knipe, D. M. (1985). Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes. J. Virol. 55, 357-365.
    • (1985) J. Virol. , vol.55 , pp. 357-365
    • Godowski, P.J.1    Knipe, D.M.2
  • 14
    • 0345662686 scopus 로고
    • Transcriptional control of herpesvirus gene expression: Gene functions required for positive and negative regulation
    • Godowski, P. J., and Knipe, D. M. (1986). Transcriptional control of herpesvirus gene expression: Gene functions required for positive and negative regulation. Proc. Natl. Acad. Sci. USA 83, 256-260.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 256-260
    • Godowski, P.J.1    Knipe, D.M.2
  • 15
    • 0019504620 scopus 로고
    • Cloning of herpes simplex virus type 1 sequences representing the whole genome
    • Goldin, A. L., Sandri-Goldin, R. M., Levine, M., and Glorioso, J. C. (1981). Cloning of herpes simplex virus type 1 sequences representing the whole genome. J. Virol. 38, 50-58.
    • (1981) J. Virol. , vol.38 , pp. 50-58
    • Goldin, A.L.1    Sandri-Goldin, R.M.2    Levine, M.3    Glorioso, J.C.4
  • 16
    • 0028149276 scopus 로고
    • Transcriptional activation of the herpes virus type 1 UL38 promoter conferred by the cis-acting downstream activation sequence is mediated by a cellular transcription factor
    • Guzowski, J. F., Singh, J., and Wagner, E. K. (1994). Transcriptional activation of the herpes virus type 1 UL38 promoter conferred by the cis-acting downstream activation sequence is mediated by a cellular transcription factor. J. Virol. 68, 7774-7789.
    • (1994) J. Virol. , vol.68 , pp. 7774-7789
    • Guzowski, J.F.1    Singh, J.2    Wagner, E.K.3
  • 17
    • 0027240438 scopus 로고
    • Mutational analysis of the herpes simplex virus type 1 strict late UL38 promoter/leader reveals two regions critical in transcriptional regulation
    • Guzowski, J. F., and Wagner, E. K. (1993). Mutational analysis of the herpes simplex virus type 1 strict late UL38 promoter/leader reveals two regions critical in transcriptional regulation. J. Virol. 67, 5098-5108.
    • (1993) J. Virol. , vol.67 , pp. 5098-5108
    • Guzowski, J.F.1    Wagner, E.K.2
  • 18
    • 0021367342 scopus 로고
    • Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: Coordinates 0.29 to 0.45
    • Holland, L. E., Sandri-Goldin, R. M., Goldin, A. L., Glorioso, J. C., and Levine, M. (1984). Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45. J. Virol. 49, 947-959.
    • (1984) J. Virol. , vol.49 , pp. 947-959
    • Holland, L.E.1    Sandri-Goldin, R.M.2    Goldin, A.L.3    Glorioso, J.C.4    Levine, M.5
  • 19
    • 0016162063 scopus 로고
    • Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins
    • Honess, R. W., and Roizman, B. (1974). Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. J. Virol. 14, 8-19.
    • (1974) J. Virol. , vol.14 , pp. 8-19
    • Honess, R.W.1    Roizman, B.2
  • 20
    • 0028145859 scopus 로고
    • The herpes simplex virus type 1 major capsid protein (VP5-UL19) promoter contains two cis-acting elements influencing late expression
    • Huang, C. J,. and Wagner, E. K. (1994). The herpes simplex virus type 1 major capsid protein (VP5-UL19) promoter contains two cis-acting elements influencing late expression. J. Virol. 68, 5738-5747.
    • (1994) J. Virol. , vol.68 , pp. 5738-5747
    • Huang, C.J.1    Wagner, E.K.2
  • 21
    • 0020424205 scopus 로고
    • Characterization of two conformational forms of the major DNA-binding protein encoded by herpes simplex virus 1
    • Knipe, D. M., Quinlan, M. P., and Spang, A. E. (1982). Characterization of two conformational forms of the major DNA-binding protein encoded by herpes simplex virus 1. J. Virol. 44, 736-741.
    • (1982) J. Virol. , vol.44 , pp. 736-741
    • Knipe, D.M.1    Quinlan, M.P.2    Spang, A.E.3
  • 22
    • 0019973281 scopus 로고
    • Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus
    • Knipe, D. M., and Spang, A. E. (1982). Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus. J Virol. 43, 314-324.
    • (1982) J Virol. , vol.43 , pp. 314-324
    • Knipe, D.M.1    Spang, A.E.2
  • 23
    • 0020597229 scopus 로고
    • Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1
    • Lee, C. K., and Knipe, D. M. (1983). Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1. J. Virol. 46, 909-919.
    • (1983) J. Virol. , vol.46 , pp. 909-919
    • Lee, C.K.1    Knipe, D.M.2
  • 24
    • 0030048573 scopus 로고    scopus 로고
    • Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures
    • Liptak, L. M., Uprichard, S. L., and D. M. Knipe, (1996). Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures. J. Virol. 70, 1759-1767.
    • (1996) J. Virol. , vol.70 , pp. 1759-1767
    • Liptak, L.M.1    Uprichard, S.L.2    Knipe, D.M.3
  • 25
    • 0016724426 scopus 로고
    • Mode of inhibition of herpes simplex virus DNA polymerase by phosphonoacetate
    • Mao, J. C. H., and Robishaw, E. E. (1975). Mode of inhibition of herpes simplex virus DNA polymerase by phosphonoacetate. Biochemistry 14, 5475-5479.
    • (1975) Biochemistry , vol.14 , pp. 5475-5479
    • Mao, J.C.H.1    Robishaw, E.E.2
  • 27
    • 0022354892 scopus 로고
    • Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1
    • McGeoch, D. J., Dolan, A., Donald, S., and Rixon, F. J. (1985). Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1. J. Mol. Biol. 181, 1-13.
    • (1985) J. Mol. Biol. , vol.181 , pp. 1-13
    • McGeoch, D.J.1    Dolan, A.2    Donald, S.3    Rixon, F.J.4
  • 28
    • 0019295352 scopus 로고
    • The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene
    • McKnight, S. L. (1980). The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. Nucleic Acids Res. 8, 5949-5964.
    • (1980) Nucleic Acids Res. , vol.8 , pp. 5949-5964
    • McKnight, S.L.1
  • 29
    • 0023123932 scopus 로고
    • Expression of herpes simplex virus type 1 major DNA-binding protein, ICP8, in transformed cell lines: Complementation of deletion mutants and inhibition of wild-type virus
    • Orberg, P. K., and Schaffer, P. A. (1987). Expression of herpes simplex virus type 1 major DNA-binding protein, ICP8, in transformed cell lines: Complementation of deletion mutants and inhibition of wild-type virus. J. Virol. 61, 1136-1146.
    • (1987) J. Virol. , vol.61 , pp. 1136-1146
    • Orberg, P.K.1    Schaffer, P.A.2
  • 30
    • 0021912943 scopus 로고
    • A noninverting genome of a viable herpes simplex virus 1 : Presence of head-to-tail linkages in packaged genomes and requirements for circularization after infection
    • Poffenberger, K. L., and Roizman, B. (1985). A noninverting genome of a viable herpes simplex virus 1 : Presence of head-to-tail linkages in packaged genomes and requirements for circularization after infection. J. Virol. 53, 587-595.
    • (1985) J. Virol. , vol.53 , pp. 587-595
    • Poffenberger, K.L.1    Roizman, B.2
  • 31
    • 0018337950 scopus 로고
    • Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK
    • Preston, C. M. (1979). Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK. J. Virol. 29, 275-284.
    • (1979) J. Virol. , vol.29 , pp. 275-284
    • Preston, C.M.1
  • 32
    • 0020701259 scopus 로고
    • Nuclear localization of herpesvirus proteins: Potential role for the cellular framework
    • Quinlan, M. P., and Knipe, D. M. (1983). Nuclear localization of herpesvirus proteins: potential role for the cellular framework. Mol. Cell. Biol. 3, 315-324.
    • (1983) Mol. Cell. Biol. , vol.3 , pp. 315-324
    • Quinlan, M.P.1    Knipe, D.M.2
  • 33
    • 0022432553 scopus 로고
    • DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein
    • Quinn, J. P., and McGeoch, D. J. (1985). DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein. Nucleic Acids Res. 13, 8143-8163.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 8143-8163
    • Quinn, J.P.1    McGeoch, D.J.2
  • 34
    • 0021338285 scopus 로고
    • Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1
    • Rafield, L. F., and Knipe, D. M. (1984). Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1. J. Virol. 49, 960-969.
    • (1984) J. Virol. , vol.49 , pp. 960-969
    • Rafield, L.F.1    Knipe, D.M.2
  • 35
    • 0025239388 scopus 로고    scopus 로고
    • Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27
    • Rice, S. A., and Knipe, D. M. (1996). Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27. J. Virol. 64, 1704-1715.
    • (1996) J. Virol. , vol.64 , pp. 1704-1715
    • Rice, S.A.1    Knipe, D.M.2
  • 36
    • 0000595684 scopus 로고
    • Herpes simplex viruses and their replication
    • (B. N. Fields, D. M. Knipe, and P. M. Howley, Eds.) Lippincott-Raven, Philadelphia, PA
    • Roizman, B., and Sears, A. E. (1990). Herpes simplex viruses and their replication. In "Virology, 3rd ed." (B. N. Fields, D. M. Knipe, and P. M. Howley, Eds.), pp. 2231-2295. Lippincott-Raven, Philadelphia, PA.
    • (1990) Virology, 3rd Ed. , pp. 2231-2295
    • Roizman, B.1    Sears, A.E.2
  • 37
    • 0022268933 scopus 로고
    • Herpes simplex virus type 1 ICP27 is an essential regulatory protein
    • Sacks, W. R., Greene, C. C., Ashman, D. P., and Schaffer, P. A. (1985). Herpes simplex virus type 1 ICP27 is an essential regulatory protein. J. Virol. 55, 796-805.
    • (1985) J. Virol. , vol.55 , pp. 796-805
    • Sacks, W.R.1    Greene, C.C.2    Ashman, D.P.3    Schaffer, P.A.4
  • 39
    • 0023274026 scopus 로고
    • Transcriptional and posttranscriptional controls establish the cascade of herpes simplex virus protein synthesis
    • Weinheimer, S. P., and McKnight, S. L. (1987). Transcriptional and posttranscriptional controls establish the cascade of herpes simplex virus protein synthesis. J. Mol. Biol. 195, 819-833.
    • (1987) J. Mol. Biol. , vol.195 , pp. 819-833
    • Weinheimer, S.P.1    McKnight, S.L.2
  • 40
    • 0027282490 scopus 로고
    • Unusual regulation of expression of the herpes simplex virus DNA polymerase gene
    • Wobbe, K. K., Digard, P., Staknis, D., and Coen, D. M. (1993). Unusual regulation of expression of the herpes simplex virus DNA polymerase gene. J. Virol. 67, 5419-5425.
    • (1993) J. Virol. , vol.67 , pp. 5419-5425
    • Wobbe, K.K.1    Digard, P.2    Staknis, D.3    Coen, D.M.4
  • 41
    • 0023848514 scopus 로고
    • Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis
    • Wu, C. A., Nelson, N. J., McGeoch, D. J., and Challberg, M. D. (1988). Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis. J. Virol. 62, 435-443.
    • (1988) J. Virol. , vol.62 , pp. 435-443
    • Wu, C.A.1    Nelson, N.J.2    McGeoch, D.J.3    Challberg, M.D.4
  • 42
    • 0023128421 scopus 로고
    • The effect of elevated levels of herpes simplex virus alpha-gene products on the expression of model early and late genes in vivo
    • Zhang, Y. F., Devi-Rao, G. B., Rice, M., Sandri-Goldin, RM., and Wagner, E. K. (1987). The effect of elevated levels of herpes simplex virus alpha-gene products on the expression of model early and late genes in vivo. Virology 157, 99-106.
    • (1987) Virology , vol.157 , pp. 99-106
    • Zhang, Y.F.1    Devi-Rao, G.B.2    Rice, M.3    Sandri-Goldin, R.M.4    Wagner, E.K.5


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