Metabolic inhibition potentiates oxidant-mediated injury of the endothelial cytoskeleton

Journal of Surgical Research

Volumn 64, Issue 1, 1996, Pages 79-88

  Delius, Ralph E ^a   Dezan, Jeanette ^a   Omann, Geneva M ^a,b   Hinshaw, Daniel B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDIZING AGENT;

ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL PERMEABILITY; CATTLE; CELL SHAPE; CELL VIABILITY; CYTOSKELETON; DRUG INDUCED DISEASE; ENDOTHELIUM CELL; ISCHEMIA; METABOLIC REGULATION; MICROFILAMENT; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 0030586035     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1996.0310     Document Type: Article

References (20)

1. 1. Shasby, D. M., Shasby, S. S., Sullivan, J. M., and Peach, M. J. Role of endothelial cytoskeleton in control of endothelial permeability. Circ. Res. 51: 657, 1982.
2. 2. Grosso, M. A., Brown, J. M., Viders, D. E., et al. Xanthine oxidase-derived oxygen radicals induce pulmonary edema via direct endothelial injury. J. Surg. Res. 46: 355, 1989.
3. 3. Kennedy, T. P., Rao, N. V., Hopkins, C., Pennnington, L., Tolley, E., and Hoidal, J. R. Role of reactive oxygen species in reperfusion injury of the rabbit lung. J. Clin. Invest. 83: 1326, 1989.
4. 4. Lynch, M. J., Grum, C. M., Gallagher, K. P., Bolling, S. F., Deeb, G. M., and Morganroth, M. L. Xanthine oxidase inhibition attenuates ischemic-reperfusion lung injury. J. Surg. Res. 44: 538, 1988.
5. 5. Patt, A., Harken, A. H., Burton, L. K., et al. Xanthine oxidanse-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains. J. Clin. Invest. 81: 1556, 1988.
6. 6. Korthius, R. J., Granger, D. N., Townsley, M. I., and Taylor, A. E. The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletalmuscle vascular permeability. Circ. Res. 57: 599, 1985.
7. 7. Henson, P. M., and Johnston, R. B. Tissue injury in inflammation. J. Clin. Invest. 79: 669, 1987.
8. 8. Bellomo, G., Mirabelli, F., Vairetti, M., Iosi, F., and Malorni, W. Cytoskeleton as a target in menadione-induced oxidative stress in cultured mammalian cells. I. Biochemical and immunocytochemical features. J. Cell. Physiol. 140: 118, 1990.
9. 9. Hinshaw, D. B., Armstrong, B. C., Burger, J. M., Beals, T. H., and Hyslop, P. A. ATP and microfilaments in cellular oxidant injury. Am. J. Pathol 132: 479, 1988.
10. 10. Hinshaw, D. B., Burger, J. M., Armstrong, B. A., and Hyslop, P. A. Mechanism of endothelial cell shape change in oxidant injury. J. Surg. Res. 46: 339, 1989.
11. 11. Hinshaw, D. B., Sklar, L. A., Bohl, B., et al. Cytoskeletal and morphologic impact of cellular oxidant injury. Am. J. Pathol. 123: 454, 1986.
12. 12. Delius, R. E., and Hinshaw, D. B. Metabolic inhibition potentiates oxidant injury. J. Surg. Res. 50: 314, 1991.
13. 13. Gores, G. J., Niemann, A. L., Fleishmann, K. E., Dawson, T. L., Herman, B., and Lemasters, J. J. Extracellular acidosis delays onset of cell death in ATP depleted hepatocytes. Am. J. Physiol. 255: C315, 1988.
14. 14. Goldman, G., Welbourn, R., Alexander, S., et al. Modulation of pulmonary permeability in vivo with agents that affect the cytoskeleton. Surgery 190: 533, 1991.
15. 15. Hinshaw, D. B., Armstrong, B. A., Beals, T. F., and Hyslop, P. A. A cellular model of endothelial cell ischemia. J. Surg. Res. 44: 527, 1988.
16. 16. Hinshaw, D. B., Burger, J. M., Miller, M. T., Adams, J. A., Beals, T. F., and Omann, G. M. ATP depletion induces an increase in the assembly of a labile pool of polymerized actin in endothelial cells. Am. J. Physiol. 264 (Cell. Physiol. 33): C1171, 1993.
17. +-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion. J. Clin. Invest. 88: 462, 1991.
18. 18. Molitoris, B. A. Ischemia induced loss of epithelial polarity: Potential role of the actin cytoskeleton. Am. J. Physiol. 260: (Cell. Physiol. 29): F769, 1991.
19. 19. Holman, R. G., and Maier, R. V. Oxidant-induced endothelial leak correlates with decreased cellular energy levels. Am. Rev. Respir. Dis. 141: 134, 1990.
20. 20. Wilson, J., Winter, M., and Shasby, D. M. Oxidants, ATP depletion, and endothelial permeability to macromolecules. Blood 76: 2578, 1990.