Closing the gap on DNA ligase

Structure

Volumn 4, Issue 6, 1996, Pages 653-656

  Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; NUCLEOTIDYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE (ATP);

AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; REVIEW; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA LIGASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDYLTRANSFERASES; PROTEIN CONFORMATION;

EID: 0030585422     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(96)00070-6     Document Type: Article

References (10)

1. Wei, Y., et al., & Lindahl, T. (1995). Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol. Cell. Biol. 15, 3206-3216.
2. Subramanya, H.S., Doherty, A. J., Ashford, S.R., & Wigley, D.B. (1996). Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7. Cell 85, 607-615.
3. Lehman, I.R. (1974). DNA ligase: structure, mechanism, and function. Science 186, 790-797.
4. Shuman, S. & Schwer, B. (1995). RNA capping enzyme and DNA ligase - a superfamily of covalent nucleotidyl transferases. Mol. Microbiol. 17, 405-410.
5. Shuman, S., Liu, Y. & Schwer, B. (1994). Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases. Proc. Natl. Acad. Sci. USA 91, 12046-12050.
6. Cong, P. & Shuman, S. (1995). Mutational analysis of mRNA capping enzyme identifies amino acids involved in GTP binding, enzyme - guanylate complex formation, and GMP transfer to RNA. Mol. Cell. Biol. 15, 6222-6231.
7. Kodama, K., Barnes, D.E. & Lindahl, T. (1991). In vitro mutagenesis and functional expression in Escherichia coli of a cDNA encoding the catalytic domain of human DNA ligase I. Nucleic Acids Res. 19, 6093-6099.
8. Shuman, S. & Ru, X. (1995). Mutational analysis of vaccinia DNA ligase defines residues essential for covalent catalysis. Virology 211, 73-83.
9. Shuman, S. (1995). Vaccinia DNA ligase: specificity, fidelity, and inhibition. Biochemistry 34, 16138-16147.
10. Montecucco, A., et al., & Biamonti, G. (1995) The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication. EMBO J. 14, 5379-5386.