Use of alternative polyadenylation sites in the synthesis of mRNAs encoding the interferon-induced tryptophanyl tRNA synthetase

Gene

Volumn 179, Issue 2, 1996, Pages 225-229

  Shen, Tong ^a,b   Anderson, Sylvia L ^a   Rubin, Berish Y ^a  

^a FORDHAM UNIVERSITY   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Differential display analysis; Northern blot; PCR; Recombinant DNA

Indexed keywords

MESSENGER RNA; TRYPTOPHAN TRANSFER RNA LIGASE;

ALTERNATIVE RNA SPLICING; ARTICLE; DNA LIBRARY; HUMAN; MESSENGER RNA SYNTHESIS; NORTHERN BLOTTING; POLYADENYLATION; PRIORITY JOURNAL; STEM CELL;

ALTERNATIVE SPLICING; BASE SEQUENCE; DNA, COMPLEMENTARY; GENE EXPRESSION; HUMANS; INTERFERONS; MOLECULAR SEQUENCE DATA; POLY A; RNA, MESSENGER; TRYPTOPHAN-TRNA LIGASE;

EID: 0030583748     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00361-7     Document Type: Article

References (18)

1. Anderson, S.L., Shen, T., Lou, J., Xing, L., Blachere, N.E., Srivastava, P.K. and Rubin, B.Y. (1994) The endoplasmic reticular heat shock protein gp96 is transcriptionally upregulated in interferon-treated cells. J. Exp. Med. 180, 1565-1569.
2. Buwitt, U., Flohr, T. and Bottger, E.C. (1992a) Molecular cloning and characterization of an interferon induced human cDNA with sequence homology to a mammalian peptide chain release factor. EMBO J. 11, 489-496.
3. Buwitt, U., Flohr, T. and Bottger, E.C. (1992b) Molecular cloning and characterization of an interferon induced human cDNA with sequence homology to a mammalian peptide chain release factor. GenBank Locus HSIFP53.
4. Fleckner, J., Rasmussen, H.H. and Justesen, J. (1991) Human interferon gamma potently induces the synthesis of a 55-kDa protein (gamma 2) highly homologous to rabbit peptide chain release factor and bovine tryptophanyl-tRNA synthetase. Proc. Natl. Acad. Sci. USA 88, 11520-11524.
5. Francke, U., Denney, R.M., and Ruddle, F.N. (1977) Intrachromosomal gene mapping in man: the gene for tryptophanyl-tRNA synthetase maps in region q21-qter of chromosome 14. Somat. Cell. Genet. 3, 381-389.
6. Frovola, L.Y., Grigorieva, A.Y., Sudomoina, M.A., and Kisselev, L.L. (1993) The human gene encoding tryptophanyl-tRNA synthetase: interferon-response elements and exon-intron organization. Gene 128, 237-245.
7. Hesketh, J., Campbell, G., Piechaczyk, M. and Blanchard, J.M. (1994) Targeting of c-myc and beta-globin coding sequences to cytoskeletal-bound polysemes by c-myc 3′ untranslated region. Biochem. J. 298, 143-148.
8. Johnson, H.M. (1987) Interferon-mediated modulation of the immune system. In: L.M. Pfeffer (Ed.), Mechanisms of IFN Actions, Vol. II. CRC Press, Boca Raton, FL, pp. 59-77.
9. Kislauskis, E.H., Li, Z.F., Singer, R.H. and Taneja, K.L. (1993) Isoform-specific 3′-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments. J. Cell Biol. 123, 165-172.
10. Liang, P. and Pardee, A.B. (1992) Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257, 967-970.
11. Pajot, B., Sarger, C., Bonnet, J. and Garret, M. (1994) An alternative splicing modifies the C-terminal end of tryptophanyl-tRNA synthetase in murine embryonic stem cells. J. Mol. Biol. 242, 599-603.
12. Pestka, S., Langer, J.A., Zoon, K.C. and Samuel, C.E. (1987) Interferons and their actions. Annu. Rev. Biochem. 56, 727-777.
13. Rubin, B.Y., Anderson, S.L., Xing, L., Powell, R.J. and Tate, W.P. (1991) Interferon induces tryptophanyl-tRNA synthetase expression in human fibroblasts. J. Biol. Chem. 266, 24245-24248.
14. Sen, G.C. (1991) Transcriptional regulation of interferon-inducible genes. In: Cohen, P. and Foulkes, J.G. (Eds.), The Hormonal Control of Gene Transcription. Elsevier, Amsterdam, pp. 349-374.
15. Sen, G.C. and Lengyel, P. (1992) The interferon system. A bird's eye view of its biochemistry. J. Biol. Chem. 267, 5017-5020.
16. Staeheli, P. (1990) Interferon-induced proteins and the antiviral state. Adv. Virus Res. 38, 147-200.
17. Sun, J., Pilch, D.R. and Marzluff, W.F. (1992) The histone mRNA 3′ end is required for localization of histone mRNA to polyribosomes. Nucleic Acids Res. 20, 6057-6066.
18. Tolstrup, A.B., Bejder, J.F., Fleckner, J. and Justesen, J. (1995) Transcriptional regulation of the interferon-γ-inducible tryptophanyl-tRNA synthetase includes alternative splicing. J. Biol. Chem. 270, 397-403.