Slow-binding inhibition: The general case

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1298, Issue 1, 1996, Pages 78-86

  Sculley, Michael J ^a,c   Morrison, John F ^a   Cleland, W Wallace ^b  

^a Australian National University   (Australia)

^b UNIVERSITY OF WISCONSIN   (United States)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Enzyme inhibition; Kinetic mechanism; Slow binding; Theoretical analysis

Indexed keywords

ARTICLE; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ENZYME MECHANISM; KINETICS; PRIORITY JOURNAL; TECHNIQUE; THEORY;

CHEMISTRY; ENZYME INHIBITORS; KINETICS; MODELS, CHEMICAL; PROTEIN BINDING;

EID: 0030583729     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(96)00118-5     Document Type: Article

References (7)

1. [1] Morrison, J.F. (1982) Trends Biochem. Sci. 7, 102-105.
2. [2] Morrison, J.F. and Walsh, C.T. (1988) Adv. Enzymol. 61, 201-301.
3. [3] Morrison, J.F. and Stone, S.R. (1985) Comments Mol. Cell Biophys. 2, 347-368.
4. [4] Sculley, M.J. and Morrison, J.F. (1986) Biochim. Biophys. Acta 874, 44-53.
5. [5] Appleman, J.R., Howell, E.E., Kraut, J., Kuhl, M. and Blakley, R.L. (1988) J. Biol. Chem. 263, 9187-9198.
6. [6] Frost, A.A. and Pearson, R.G. (1961) Kinetics and Mechanism, 2nd ed., 175 pp., Wiley, New York.
7. [7] Cleland, W.W. (1979) Methods Enzymol. 63, 103-138.