Gonadal hormones and picrotoxin-induced convulsions in male and female rats

Brain Research

Volumn 736, Issue 1-2, 1996, Pages 174-179

  Peričić, Danka ^a   Manev, Hari ^a   Bujas, Maja ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

convulsion; gonadal hormone; picrotoxin; picrotoxin induced; rat; sex difference; TBOB binding

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ESTRADIOL; PICROTOXIN; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVULSION; FEMALE; GABAERGIC SYSTEM; GONADECTOMY; HORMONE BLOOD LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SEX DIFFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030583626     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00677-4     Document Type: Article

References (40)

1. [1] Canonaco, M., Tavolaro, R. and Maggi, A., Steroid hormones and receptors of the GABA supramolecular complex, Neuroendocrinology, 57 (1993) 974-984.
2. [2] Earley, C.J. and Leonard, B.E., GABA and gonadal hormones, Brain Res., 155 (1978) 27-34.
3. [3] Fink, G., Sarkar, D.K., Dow, R.C., Dick, H., Borthwick, N., Malnick, S. and Twine, M., Sex differences in response to alphaxalone anaesthesia may be oestrogen dependent, Nature, 298 (1982) 270-272.
4. [4] Finn, D.A. and Gee, K.W., The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid, J. Pharmacol. Exp. Ther., 271 (1994) 164-170.
5. [5] Finney, D.J., Latscha, R., Bennett, B.M., Hsu, P. and Pearson, E.S., Tables for Testing Significance in a 2 × 2 Contingency Table, Cambridge University Press, Cambridge, 1963.
6. [6] Fiszer de Plazas, S., Seilicovich, A., Duvilanski, B., Gonzales, N.N. and Rettori, V., Sex related differences in GABA binding sites of rat anterior pituitary and hypothalamus, IRCS Med. Sci., 11 (1983) 976.
7. [7] Frankfurt, M., Fuchs, E. and Wuttke, W., Sex differences in γ-aminobutyric acid and glutamate concentrations in discrete rat brain nuclei, Neurosci. Lett., 50 (1984) 245-250.
8. [8] Guillet, R. and Dunham, L., Neonatal caffeine exposure and seizure susceptibility in adult rats, Epilepsia, 36 (1995) 743-749.
9. [9] Hamon, M., Goetz, C., Euvrard, C., Pasqualini, C., Le Dafneit, M., Kerdelhere, B., Cesbini, F. and Peillon, F., Biochemical and functional alterations of central GABA receptors during chronic estradiol treatment, Brain Res., 279 (1983) 141-152.
10. [10] Juptner, M. and Hiemke, C., Sex difference in GABA receptor binding in rat brain measured by an improved in vitro binding assay, Exp. Brain. Res., 81 (1990) 297-302.
11. [11] Kellogg, C.K., Primus, R.J. and Bitran, D., Sexually dimorphic influence of prenatal exposure to diazepam on behavioral responses to environmental challenge and on γ-aminobutyric acid (GABA)-stimulated chloride uptake in the brain, J. Pharmacol. Exp. Ther., 256 (1991) 259-265.
12. [12] Kokka, N., Sapp, D.W., Witte, U. and Olsen, R.W., Sex differences in sensitivity to pentylenetetrazol but not in GABA receptor binding, Pharmacol. Biochem. Behav., 43 (1992) 441-447.
13. [13] Lasaga, M., Duvilanski, B.H., Seilicovich, A., Afione, S. and Debeljuk, L., Effects of sex steroids on GABA receptors in the rat hypothalamus and anterior pituitary gland, Eur. J. Pharmacol., 155 (1988) 163-166.
14. 3H]Butylbicycloorthobenzoate: new radioligand probe for the γ-aminobutyric acid-regulated chloride ionophore, J. Neurochem., 45 (1985) 798-804.
15. [15] Maggi, A. and Perez. J., Progesterone and estrogens in rat brain: Modulation of GABA (γ-aminobutyric acid) receptor activity, Eur. J. Pharmacol., 103 (1984) 165-168.
16. [16] Maggi, A. and Perez, J., Role of female gonadal hormones in the CNS: Clinical and experimental aspects, Life Sci., 37 (1985) 893-906.
17. [17] Maggi, A. and Perez, J., Estrogen-induced up-regulation of gamma-aminobutyric acid receptors in the CNS of rodents, J. Neurochem., 47 (1986) 1793-1797.
18. [18] Majewska, M.D., Harrison, N.L., Schwartz, R.D., Barker, J.L. and Paul, S.M., Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor, Science, 232 (1986) 1004-1007.
19. [19] Majewska, M.D. and Schwartz, R.D., Pregnenolone-sulfate: An endogenous antagonist of the γ-aminobutyric acid receptor complex in brain?, Brain Res., 404 (1987) 355-360.
20. [20] Manev, H. and Peričić, D., Sex difference in the turnover of GABA in the rat substantia nigra, J. Neural.Transm., 70 (1987) 321-328.
21. [21] Manev, H., Peričić, D. and Anić-Stojiljković, S., Sex differences in the sensitivity of CBA mice to convulsions induced by GABA antagonists are age-dependent, Psychopharmacology, 91 (1987) 226-229.
22. [22] Manyam, B.V. and Hare, T.A., Cerebrospinal fluid GABA measurements: Basic and clinic consideration, Clin. Neuropharmacol., 6 (1983) 25-36.
23. 3H]muscimol binding in the spinal cord of the rat, Brain Res., 556 (1991) 321-323.
24. [24] McGinnis, M.Y., Gordon, J.H. and Gorski, R.A., Time course and localization of the effects of estrogen on glutamic acid decarboxylase activity, J. Neurochem., 34 (1980) 785-792.
25. [25] McPherson, G.A., A practical computer-based approach to the analysis of radioligand binding experiments, Comput. Progr. Biomed., 17 (1983) 107-114.
26. [26] Nicoletti, F. and Meek, J.L., Estradiol decreases nigral GABAergic activity in male rats, Brain Res., 332 (1985) 179-183.
27. [27] O'Connor, L.H., Nock, B. and McEwen, B.S., Regional specificity of gamma-aminobutyric acid receptor regulation by estradiol, Neuroendocrinology, 47 (1988) 473-481.
28. [28] Olsen, R.W., Ticku, M.K., Van Ness, P.L. and Greenlee, D., Effects of drugs on γ-aminobutyric acid receptors, uptake, release and synthesis in vitro, Brain Res., 139 (1978) 277-294.
29. [29] Perez, J., Zucchi, I. and Maggi, A., Sexual dimorphism in the response of the GABAergic system to estrogen administration, J. Neurochem., 47 (1986) 1798-1803.
30. [30] Peričić, D. and Manev, H., Effect of dihydroergosine on the susceptibility of rats to convulsions produced by different convulsant agents, Psychopharmacology, 80 (1983) 171-173.
31. [31] Peričić, D., Manev, H. and Geber, J., Sex related differences in the response of mice, rats and cats to administration of picrotoxin, Life Sci., 38 (1986) 905-913.
32. [32] Peričić, D., Manev, H. and Lakić, N., Sex differences in the response of rats to drugs affecting GABAergic transmission, Life Sci., 36 (1985) 541-547.
33. [33] Pfaff, D.W. and McEwen, B.S., Action of estrogens and progestins on nerve cells, Science, 219 (1983) 808-814.
34. [34] Rastogi, S.K. and Ticku, M.K., Anticonvulsant profile of drugs which facilitate GABAergic transmission on convulsions mediated by a GABAergic mechanisms, Neuropharmacology, 25 (1986) 175-185.
35. [35] Schumacher, M., Coirini, H. and McEwen, B.S., Regulation of high-affinity GABA receptors in specific brain regions by ovarian hormones, Neuroendocrinology, 50 (1989) 315-320.
36. [36] Schwartz-Giblin, S., Korotzer, A. and Pfaff, D.W., Steroid hormone effects on picrotoxin-induced seizures in female and male rats, Brain Res., 476 (1989) 240-247.
37. 3H-flunitrazepam cortical binding following stressful manipulations in rats, Brain Res., 189 (1980) 505-517.
38. [38] Thomas, J. and Yang, Y.-C., Allylglycine-induced seizures in male and female rats, Physiol. Behav., 49 (1991) 1181-1183.
39. [39] Tunnicliff, G., Welborn, K.L. and Noo, T.T., Identification of potential GABA-mimetics by their actions on brain GABA recognition sites, Gen. Pharmacol., 16 (1985) 25-29.
40. - ionophore in mouse brain, Eur. J. Pharmacol., 221 (1992) 139-143.