Regiospecific free radical annulation reactions of diethylbenzylmalonate with unsymmetrical 1,4-naphthoquinones: A direct approach to ring A aromatic angucyclinones

Tetrahedron Letters

Volumn 37, Issue 42, 1996, Pages 7615-7618

  Murphy, William S ^a   Neville, Daniel ^a   Ferguson, George ^b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; ANGUCYCLINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030583497     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01675-9     Document Type: Article

References (19)

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15. -1. Some 2106 reflections were measured of which 839 had I > 2(sigma)I. Structure solved by direct methods using SHELXS86 (Sheldrick, G.M. A program for the solution of crystal structures, University of Gottingen, Germany) using all 2106 measured reflections and SHELXL93(idem, ibid). H atoms allowed for as riding atoms and non-H atoms allowed anisotropic motion. Final R-factors on the 839 "observed" data are R=0.0619, wR(Fsquared) = 0.1212. The molecular geometry is entirely in accord with expectations: full details available in Crystallographic Information File (CIF) format from the authors; these details have also been deposited with the Cambridge Crystallographic Data Centre.
16. 10. All new compounds reported gave satisfactory spectroscopic and analytical data.
17. 11. Kirby, A.J. Stereoelectronic Effects; Oxford University Press Inc.: New York, 1996; pp. 82-84.
18. 13, the nature of the DEM residue -possibly a Fischer Mn-stabilised carbene complex - remains unknown.
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