Overexpression of nerve growth factor in epidermis of transgenic mice preserves excess sensory neurons but does not alter the somatotopic organization of cutaneous nerve projections

Neuroscience Letters

Volumn 211, Issue 1, 1996, Pages 68-72

  Mendelson, Bruce ^a,c   Albers, Kathryn M ^b   Goodness, Thomas P ^b   Davis, Brian M ^b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF CENTRAL ARKANSAS   (United States)

Author keywords

Cell death; Dorsal horn; Neurotrophins; Sensory neuron

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; NERVE GROWTH FACTOR;

ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; EPIDERMIS; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; MOUSE; NERVE PROJECTION; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE; SPINAL CORD DORSAL HORN; TRANSGENIC MOUSE;

EID: 0030583107     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12641-0     Document Type: Article

References (22)

1. [1] Albers, K.M., Wright, D.E. and Davis, B.M., Overexpression of nerve growth factor in epidermis of transgenic mice causes hypertrophy of the peripheral nervous system, J. Neurosci., 14 (1994) 1422-1432.
2. [2] Brown, P.B., Koerber, H.R. and Ritz, L.A., Somatotopic organization of primary afferent projections in the spinal cord. In S.A. Scott (Ed.), Sensory Neurons: Diversity, Development and Plasticity, Oxford University Press, New York, 1992, pp. 116-130.
3. [3] Byrne, C., Tainsky, M. and Fuchs, E., Programming gene expression in developing epidermis. Development, 120 (1994) 2369-2383.
4. [4] Coggeshall, R.E., Chung, K., Greenwood, D. and Hulsebosch, C., An empirical method for converting nucleolar counts to neuronal numbers, J. Neurosei. Methods, 12 (1984) 125-132.
5. [5] Coggeshall, R.E., La Forte, R. and Klein, C.M., Calibration of methods for determining numbers of dorsal root ganglion cells, J. Neurosci. Methods, 35 (1990) 187-194.
6. [6] Davies, A.M., Cell death and the trophic requirements of developing sensory neurons. In S.A. Scott (Ed.), Sensory Neurons: Diversity, Development and Plasticity, Oxford University Press, New York, 1992, pp. 194-214.
7. [7] Davies, A.M., Bandtlow, C., Heumann, R., Korsching, S., Rohrer, H. and Thoenen, H., Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor, Nature, 326 (1986) 353-358.
8. [8] Davis, B.M., Lewin, G.R., Mendell, L.M., Jones, M.E. and Albers, K.M., Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli, Neuroscience, 56 (1993) 789-792.
9. [9] Fitzgerald, M., Butcher, T. and Shortland, P., Developmental changes in the laminar termination of A fibre cutaneous sensory afferents in the rat spinal cord dorsal horn, J. Comp. Neurol., 348 (1994) 225-233.
10. [10] Fyffe, R.E.W., Laminar organization of primary afferent terminations in the mammalian spinal cord. In S.A. Scott (Ed.), Sensory Neurons: Diversity, Development and Plasticity, Oxford University Press, New York, 1992, pp. 131-139.
11. [11] Gibson, S.J., Polak, J.M., Bloom, S.R., Sabate, I.M., Mulderry, P.M., Ghatei, M.A., McGregor, G.P., Morrison, J.F.B., Kelly, J.S., Evans, R.M. and Rosenfeld, M.G., Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species, J. Neurosci., 12 (1984) 3101-3111.
12. [12] Goodman, C.S. and Shatz, C.J., Developmental mechanisms that generate precise patterns of neuronal connectivity, Neuron, 10 (1993) 77-98.
13. [13] Henderson, T.A., Johnson, E.M.J., Osborne, P.A. and Jacquin, M.F., Fetal NGF augmentation preserves excess trigeminal ganglion cells and interrupts whisker-related pattern formation, J. Neurosci., 14 (1994) 3399-3403.
14. [14] Lewin, G.R., McKintosh, E. and McMahon, S.B., NMDA receptors and activity-dependent tuning of the receptive fields of spinal cord neurons, Nature, 369 (1994) 482-485.
15. [15] Lindsay, R.M. and Harmar, A.J., Nerve growth factor regulates the expression of neuropeptide genes in adult sensory neurons, Nature, 337 (1989) 362-364.
16. [16] Mendelson, B., Chronic embryonic MK-801 exposure disrupts the somatotopic organization of cutaneous nerve projections in the chick spinal cord, Dev. Brain Res., 82 (1994) 152-166.
17. [17] Mendelson, B., Koerber, H.R. and Frank, E., Development of cutaneous and proprioceptive afferent projections in the chick spinal cord, Neurosci. Lett., 138 (1992) 72-76.
18. [18] Mimics, K. and Koerber, H.R., Prenatal development of rat primary afferent fibers, II: central projections, J. Comp. Neurol., 355 (1995) 601-614.
19. [19] O'Leary, D.D.M., Fawcett, J.W. and Cowan, W.M., Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death, J. Neurosci., 6 (1986) 3692-3705.
20. [20] Scott, S.A., The development of peripheral sensory innervation patterns. In S.A. Scott (Ed.), Sensory Neurons: Diversity, Development and Plasticity, Oxford University Press, New York, 1992, pp. 242-263.
21. [21] Silos-Santiago, I., Jeng, B. and Snider, W.D., Sensory afferents show appropriate somatotopy at the earliest stage of projection to the dorsal horn, NeuroReport, 6 (1995) 861-865.
22. [22] Smith, C.L., The development and postnatal organization of primary afferent projections to the rat thoracic spinal cord, J. Comp. Neurol., 220 (1983) 29-43.