-
1
-
-
0026649231
-
Directed evolution of an RNA enzyme
-
Beaudry, A. A. & Joyce, G. F. (1992). Directed evolution of an RNA enzyme. Science, 257, 635-641.
-
(1992)
Science
, vol.257
, pp. 635-641
-
-
Beaudry, A.A.1
Joyce, G.F.2
-
2
-
-
0025877764
-
Group I intron self-splicing with adenosine: Evidence for a single nucleoside-binding site
-
Been, M. D. & Perotta, A. T. (1991). Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site. Science, 252, 434-437.
-
(1991)
Science
, vol.252
, pp. 434-437
-
-
Been, M.D.1
Perotta, A.T.2
-
3
-
-
0026347806
-
Comparison of binding of mixed ribose-deoxyribose analogues of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: Evidence for ribozyme specific interactions with 2′-OH groups
-
Bevilacqua, P. C. & Turner, D. H. (1991). Comparison of binding of mixed ribose-deoxyribose analogues of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: evidence for ribozyme specific interactions with 2′-OH groups. Biochemistry, 30, 10632-10640.
-
(1991)
Biochemistry
, vol.30
, pp. 10632-10640
-
-
Bevilacqua, P.C.1
Turner, D.H.2
-
4
-
-
0026678180
-
Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods
-
Bevilacqua, P. C., Kierzek, R., Johnson, K. A. & Turner, D. H. (1992). Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods. Science, 258, 1355-1358.
-
(1992)
Science
, vol.258
, pp. 1355-1358
-
-
Bevilacqua, P.C.1
Kierzek, R.2
Johnson, K.A.3
Turner, D.H.4
-
5
-
-
0028472621
-
Inventing and improving ribozyme function: Rational design versus iterative selection methods
-
Breaker, R. R. & Joyce, G. F. (1994). Inventing and improving ribozyme function: rational design versus iterative selection methods. Trends Biotech. 12, 268-275.
-
(1994)
Trends Biotech.
, vol.12
, pp. 268-275
-
-
Breaker, R.R.1
Joyce, G.F.2
-
6
-
-
0020326042
-
Bacteriophage SP6-specific RNA polymerase. Isolation and characterization of the enzyme
-
Butler, E. T. & Chamberlin, M. J. (1982). Bacteriophage SP6-specific RNA polymerase. Isolation and characterization of the enzyme. J. Biol. Chem. 257, 5772-5778.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 5772-5778
-
-
Butler, E.T.1
Chamberlin, M.J.2
-
7
-
-
85045502002
-
Randomization of genes by PCR mutagenesis
-
Cadwell, R. C. & Joyce, G. F. (1992). Randomization of genes by PCR mutagenesis. PCR Methods Applic. 2, 28-33.
-
(1992)
PCR Methods Applic.
, vol.2
, pp. 28-33
-
-
Cadwell, R.C.1
Joyce, G.F.2
-
9
-
-
0028441183
-
Representation of the secondary and tertiary structure of group I introns
-
Cech, T. R., Damberger, S. H. & Gutell, R. R. (1994) Representation of the secondary and tertiary structure of group I introns. Nature Struct. Biol. 1(5), 273-280.
-
(1994)
Nature Struct. Biol.
, vol.1
, Issue.5
, pp. 273-280
-
-
Cech, T.R.1
Damberger, S.H.2
Gutell, R.R.3
-
10
-
-
0000696532
-
Cloning and expression of the gene for bacteriophage T7 RNA polymerase
-
Davanloo, P., Rosenberg, A. H., Dunn, J. J. & Studier, F. W. (1984). Cloning and expression of the gene for bacteriophage T7 RNA polymerase. Proc. Natl Acad. Sci. USA, 81, 2035-2039.
-
(1984)
Proc. Natl Acad. Sci. USA
, vol.81
, pp. 2035-2039
-
-
Davanloo, P.1
Rosenberg, A.H.2
Dunn, J.J.3
Studier, F.W.4
-
11
-
-
0029379551
-
Let's get specific: The relationship between specificity and affinity
-
Eaton, B. E., Gold, L. & Zichi, D. A. (1995). Let's get specific: the relationship between specificity and affinity. Chemistry & Biology, 2, 633-638.
-
(1995)
Chemistry & Biology
, vol.2
, pp. 633-638
-
-
Eaton, B.E.1
Gold, L.2
Zichi, D.A.3
-
12
-
-
0026556769
-
Crystal structure of an Okazaki fragment at 2-Å resolution
-
Egli, M., Usman, N., Zhang, S. & Rich, A. (1992). Crystal structure of an Okazaki fragment at 2-Å resolution. Proc. Natl Acad. Sci. USA, 89, 534-538.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 534-538
-
-
Egli, M.1
Usman, N.2
Zhang, S.3
Rich, A.4
-
13
-
-
0025084575
-
In vitro genetic analysis of the Tetrahymena self-splicing intron
-
Green, R., Ellington, A. D. & Szostak, J. W. (1990). In vitro genetic analysis of the Tetrahymena self-splicing intron. Nature, 347, 406-408.
-
(1990)
Nature
, vol.347
, pp. 406-408
-
-
Green, R.1
Ellington, A.D.2
Szostak, J.W.3
-
14
-
-
0026580844
-
Evidence for processivity and two-step binding of the RNA substrate from studies of the J1/2 mutants of the Tetrahymena ribozyme
-
Herschlag, D. (1992). Evidence for processivity and two-step binding of the RNA substrate from studies of the J1/2 mutants of the Tetrahymena ribozyme. Biochemistry, 31, 1386-1399.
-
(1992)
Biochemistry
, vol.31
, pp. 1386-1399
-
-
Herschlag, D.1
-
15
-
-
0025085590
-
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site
-
Herschlag, D. & Cech, T. R. (1990). Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. Biochemistry, 29, 10159-10171.
-
(1990)
Biochemistry
, vol.29
, pp. 10159-10171
-
-
Herschlag, D.1
Cech, T.R.2
-
16
-
-
0027209722
-
The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction
-
Herschlag, D., Eckstein, F. & Cech, T. R. (1993). The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Biochemistry, 32, 8312-8321.
-
(1993)
Biochemistry
, vol.32
, pp. 8312-8321
-
-
Herschlag, D.1
Eckstein, F.2
Cech, T.R.3
-
17
-
-
0024592256
-
A novel technique for the rapid preparation of mutant RNAs. Nucl
-
Joyce, G. F. & Inoue, T. (1989). A novel technique for the rapid preparation of mutant RNAs. Nucl. Acids Res. 17, 711-722.
-
(1989)
Acids Res.
, vol.17
, pp. 711-722
-
-
Joyce, G.F.1
Inoue, T.2
-
18
-
-
0023462809
-
Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena
-
Kim, S.-H. & Cech, T. R. (1987). Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena. Proc. Natl Acad. Sci. USA, 84, 8788-8792.
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 8788-8792
-
-
Kim, S.-H.1
Cech, T.R.2
-
19
-
-
0027525989
-
Evolution in vitro of an RNA enzyme with altered metal dependence
-
Lehman, N. & Joyce, G. (1993). Evolution in vitro of an RNA enzyme with altered metal dependence. Nature, 361, 182-185.
-
(1993)
Nature
, vol.361
, pp. 182-185
-
-
Lehman, N.1
Joyce, G.2
-
20
-
-
0030072640
-
Chance and necessity in the selection of nucleic acid catalysts
-
Lorsch, J. R. & Szostak, J. W. (1996). Chance and necessity in the selection of nucleic acid catalysts. Acc. Chem. Res. 29(2), 103-110.
-
(1996)
Acc. Chem. Res.
, vol.29
, Issue.2
, pp. 103-110
-
-
Lorsch, J.R.1
Szostak, J.W.2
-
21
-
-
0029882895
-
Mechanistic investigations of a ribozyme derived from the Tetrahymena group I intron. Insights into catalysis and the second step of splicing
-
Mei, R. & Herschlag, D. (1996). Mechanistic investigations of a ribozyme derived from the Tetrahymena group I intron. Insights into catalysis and the second step of splicing. Biochemistry, 35, 5796-5809.
-
(1996)
Biochemistry
, vol.35
, pp. 5796-5809
-
-
Mei, R.1
Herschlag, D.2
-
22
-
-
0024427177
-
The guanosine binding site of the Tetrahymena ribozyme
-
Michel, F., Hanna, M., Green, R., Bartel, D. P. & Szostak, J. W. (1989). The guanosine binding site of the Tetrahymena ribozyme. Nature, 342, 391-395.
-
(1989)
Nature
, vol.342
, pp. 391-395
-
-
Michel, F.1
Hanna, M.2
Green, R.3
Bartel, D.P.4
Szostak, J.W.5
-
23
-
-
0026427239
-
Ribozyme recognition of RNA by tertiary interactions with specific ribose 2′-OH groups
-
Pyle, A. M. & Cech, T. R. (1991). Ribozyme recognition of RNA by tertiary interactions with specific ribose 2′-OH groups. Nature, 350, 628-631.
-
(1991)
Nature
, vol.350
, pp. 628-631
-
-
Pyle, A.M.1
Cech, T.R.2
-
24
-
-
0026729278
-
RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme
-
Pyle, A. M., Murphy, F. L. & Cech, T. R. (1992). RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme. Nature, 358, 123-128.
-
(1992)
Nature
, vol.358
, pp. 123-128
-
-
Pyle, A.M.1
Murphy, F.L.2
Cech, T.R.3
-
25
-
-
0027089978
-
Stability and properties of double and triple helices: Dramatic effects of RNA or DNA backbone composition
-
Roberts, R. W. & Crothers, D. M. (1993). Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition. Science, 258, 1463-1466.
-
(1993)
Science
, vol.258
, pp. 1463-1466
-
-
Roberts, R.W.1
Crothers, D.M.2
-
27
-
-
0029160643
-
How to search for RNA structures. Theoretical concepts in evolutionary biotechnology
-
Schuster, P. (1995). How to search for RNA structures. Theoretical concepts in evolutionary biotechnology. J. Biotech. 41, 239-257.
-
(1995)
J. Biotech.
, vol.41
, pp. 239-257
-
-
Schuster, P.1
-
28
-
-
0028196714
-
From sequences to shapes and back. A case study in RNA secondary structures
-
Schuster, P., Fontana, W., Stadler, P. F. & Hofacker, I. L. (1994). From sequences to shapes and back. A case study in RNA secondary structures. Proc. Roy. Soc. ser. B, 255, 279-284.
-
(1994)
Proc. Roy. Soc. Ser. B
, vol.255
, pp. 279-284
-
-
Schuster, P.1
Fontana, W.2
Stadler, P.F.3
Hofacker, I.L.4
-
29
-
-
0028233951
-
Evolutionary optimization of a DNA-cleaving ribozyme
-
Tsang, J. & Joyce, G. F. (1994). Evolutionary optimization of a DNA-cleaving ribozyme. Biochemistry, 33, 5966-5973.
-
(1994)
Biochemistry
, vol.33
, pp. 5966-5973
-
-
Tsang, J.1
Joyce, G.F.2
-
30
-
-
0020317728
-
Molecular structure of r(GCG)d(TATACGC): A DNA-RNA hybrid helix joined to double helical DNA
-
Wang, A. H.-J., Fujii, S., van Boom, J. H., van der Marel, G. A., van Boeckel, S. A. A. & Rich, A. (1982). Molecular structure of r(GCG)d(TATACGC): a DNA-RNA hybrid helix joined to double helical DNA. Nature, 299, 601-604.
-
(1982)
Nature
, vol.299
, pp. 601-604
-
-
Wang, A.H.-J.1
Fujii, S.2
Van Boom, J.H.3
Van Der Marel, G.A.4
Van Boeckel, S.A.A.5
Rich, A.6
-
31
-
-
0022975535
-
The Tetrahymena ribozyme acts like an RNA restriction endonuclease
-
Zaug, A. J., Been, M. D. & Cech, T. R. (1986). The Tetrahymena ribozyme acts like an RNA restriction endonuclease. Nature, 324, 429-433.
-
(1986)
Nature
, vol.324
, pp. 429-433
-
-
Zaug, A.J.1
Been, M.D.2
Cech, T.R.3
-
32
-
-
0022649937
-
The intervening sequence RNA of Tetrahymena is an enzyme
-
Zaug, A. J. & Cech, T. R. (1986). The intervening sequence RNA of Tetrahymena is an enzyme. Science, 231, 470-475.
-
(1986)
Science
, vol.231
, pp. 470-475
-
-
Zaug, A.J.1
Cech, T.R.2
|