Modulation of membrane currents and mechanical activity by niflumic acid in rat vascular smooth muscle

European Journal of Pharmacology

Volumn 317, Issue 1, 1996, Pages 165-174

  Kirkup, Anthony J ^a,b   Edwards, Gillian ^a   Green, Michelle E ^a   Miller, Martin ^a   Walker, Simon D ^a   Weston, Arthur H ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Caffeine; Cl current; Glibenclamide; Niflumic acid; Noradrenaline; Smooth muscle

Indexed keywords

CAFFEINE; GLIBENCLAMIDE; NIFLUMIC ACID; NORADRENALIN;

ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONCENTRATION RESPONSE; CONDUCTANCE; CONTROLLED STUDY; MALE; MEMBRANE CURRENT; MODULATION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAFFEINE; CELL MEMBRANE; CHLORIDE CHANNELS; ELECTROPHYSIOLOGY; ION CHANNELS; MALE; MEMBRANE POTENTIALS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NIFLUMIC ACID; NOREPINEPHRINE; PATCH-CLAMP TECHNIQUES; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030581734     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00713-3     Document Type: Article

References (47)

1. 36Cl efflux and micro-electrodes, J. Physiol. 326, 139.
2. Aickin, C.C. and N.A. Vermue, 1983, Microelectrode measurement of intracellular chloride activity in smooth muscle cells of guinea pig ureter, Pflügers Arch. 397, 25.
3. Amédée, T. and W.A. Large, 1989, Microelectrode study on the ionic mechanisms which contribute to the noradrenaline-induced depolarisation in isolated cells of the rabbit portal vein, Br. J. Pharmacol. 97, 1331.
4. Amédée, T., C.D. Benham, T.B. Bolton, N.G. Byrne and W.A. Large. 1990, Potassium, chloride and non-selective cation conductances opened by noradrenaline in rabbit ear artery cells, J. Physiol. 423, 551.
5. Beech, D.J. and T.B. Bolton, 1989, Properties of the cromakalim-induced potassium conductance in smooth muscle cells isolated from the rabbit portal vein, Br. J. Pharmacol. 98, 851.
6. Boissier, J.R., J. Fichele-Pagny and Z. Horakova, 1967, Dérivés phénylaminonicotiniques anti-inflammatoires. Thérapie 22, 157.
7. Byrne, N.G. and W.A. Large, 1988, Membrane ionic mechanisms activated by noradrenaline in cells isolated from the rabbit portal vein, J. Physiol. 404, 557.
8. Cousin, J.-L. and R. Motais, 1979, Inhibition of anion permeability by amphiphilic compounds in human red cell: evidence for an interaction of niflumic acid with the band 3 protein, J. Membr. Biol. 46, 125.
9. Criddle, D.N., R. Soares de Moura, I.A. Greenwood. R.M. Helliwell and W.A. Large, 1995, Inhibitory actions of niflumic acid and nifedipine on noradrenaline-induced contraction of the isolated rat aorta, Br. J. Pharmacol. 114, 423P.
10. - currents in rat sensory neurones by flash photolysis of DM-nitrophen, J. Physiol. 482, 291.
11. + channels reveal the effects of intracellular chloride variations on cytoplasmic ATP concentrations and mitochondrial function, Biochem. Biophys. Res. Commun. 168, 113.
12. Edwards, G., T. Ibbotson and A.H. Weston, 1993. Levcromakalim may induce a voltage-independent K-current in rat portal veins by modifying the gating properties of the delayed rectifier, Br. J. Pharmacol. 110, 1037.
13. Ca channel opener, in vascular smooth muscle, Br. J. Pharmacol. 113, 1538.
14. Edwards, G., P.M. Zygmunt, E.D. Högestätt and A.H. Weston. 1996, Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein, Br. J. Pharmacol. 119, 691.
15. Greenwood, I.A. and W.A. Large, 1995, Comparison of the effects of fenamates on Ca-activated chloride and potassium currents in rabbit portal vein smooth muscle cell, Br. J. Pharmacol. 116, 2939.
16. Ham, E.A., K.J. Cirillo, M. Zanetti, T.Y. Shen and F.A. Kuehl, 1972, Studies on the mode of action of non-steroidal, anti-inflammatory agents, in: Prostaglandins in Cellular Biology, eds. P.W. Ramwell and B.B. Pharris (Plenum Press, New York) p. 345.
17. Hamill, O.P., A. Marty, E. Neher, B. Sakmann and F.J. Sigworth, 1981, Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflüg. Arch. 391, 85.
18. Hoffman, C. and A. Faure, 1966, Réactions de l'acide chloro-2-nicotinique (ler mémoire). Condensations avec les amines aromatiques, Bull. Soc. Chim. Fr. 7, 2316.
19. Hogg, R.C., Q. Wang, R.M. Helliwell and W.A. Large, 1993a, Properties of spontaneous inward currents in rabbit pulmonary artery smooth muscle cells. Pflüg. Arch. 425, 233.
20. Hogg, R.C., Q. Wang and W.A. Large, 1993b, Time course of spontaneous calcium-activated chloride currents in smooth muscle cells from the rabbit portal vein, J. Physiol. 464, 15.
21. Hogg, R.C., Q. Wang and W.A. Large, 1994a, Effects of Cl channel blockers on Ca-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein, Br. J. Pharmacol. 111, 1333.
22. Hogg, R.C., Q. Wang and W.A. Large, 1994b, Action of niflumic acid on evoked and spontaneous calcium-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein, Br. J. Pharmacol. 112, 977.
23. Horn, R. and A. Marty, 1988. Muscarinic activation of ionic currents measured by a new whole-cell recording method. J. Gen. Physiol. 92, 145.
24. Hughes, B.A. and Y. Segawa, 1993, cAMP-activated chloride currents in amphibian retinal pigment epithelial cells, J. Physiol. 466, 749.
25. Ibbotson, T., G. Edwards, Th. Noack and A.H. Weston, 1993a, Effects of P1060 and aprikalim on whole-cell currents in rat portal vein; inhibition by glibenclamide and phentolamine, Br. J. Pharmacol. 108, 991.
26. Ibbotson, T., G. Edwards and A.H. Weston, 1993b, Antagonism of levcromakalim by imidazoline-and guanidine derivatives in rat portal vein: involvement of the delayed rectifier, Br. J. Pharmacol. 110, 1556.
27. 2+ channels but not the ryanodine receptor, Biochem. J. 306, 679.
28. Jetley, M. and A.H. Weston, 1980, Some effects of sodium nitroprusside, methoxyverapamil (D600) and nifedipine on rat portal vein, Br. J. Pharmacol. 68, 311.
29. Kirkup, A.J., G. Edwards and A.H. Weston, 1994, The effects of niflumic acid on noradrenaline-induced chloride currents and mechanical responses of the rat portal vein, Br. J. Pharmacol. 112, 56P.
30. Kirkup. A.J., G. Edwards and A.H. Weston, 1996. Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid on membrane currents in rat portal vein, Br. J. Pharmacol. 117, 175.
31. 2+-dependent chloride current in mouse pituitary cells, J. Physiol. 439, 423.
32. Lamb, F.S., K.A. Volk and E.F. Shibata, 1994. Calcium-activated chloride current in rabbit coronary artery myocytes. Circ. Res. 75, 742.
33. Leprêtre, N., J. Mironneau, S. Arnaudeau, Z. Tanfin, S. Harbon, G. Guillon and J. Ibarrondo, 1994, Activation of alpha-1A adrenoceptors mobilises calcium from the intracellular stores in myocytes from rat portal vein, J. Pharmacol. Exp. Ther. 268, 167.
34. - channels in rat portal vein myocytes, J. Biol. Chem. 267, 4312.
35. Lukacs, G.L., A. Nanda, O.D. Rotstein and S. Grinstein, 1991, The chloride channel blocker 5-nitro-2-(3-phenylpropyl-amino) benzoic acid (NPPB) uncouples mitochondria and increases the proton permeability of the plasma membrane in phagocytic cells, FEBS Lett. 288, 17.
36. - current in avian salt gland cells, Regul. Pept. 52, 205.
37. Marty, A., Y.P. Tan and A. Trautmann, 1984, Three types of calcium-dependent channel in rat lacrimal glands, J. Physiol. 357, 293.
38. Noack, Th., P. Deitmer and K. Golenhofen, 1990, Features of a calcium independent, caffeine sensitive outward current in single smooth muscle cells from guinea-pig portal vein, Pflüg. Arch. 416, 467.
39. Noack, Th., P. Deitmer, G. Edwards and A.H. Weston, 1992, Characterisation of potassium currents modulated by BRL 38227 in rat portal vein, Br. J. Pharmacol. 106, 717.
40. Pacaud, P., G. Loirand, J.L. Lavie, C. Mironneau and J. Mironneau, 1989a, Calcium-activated chloride current in rat vascular smooth muscle cells in short-term primary culture, Pflüg. Arch. 413, 629.
41. Pacaud, P., G. Loirand, C. Mironneau and J. Mironneau, 1989b, Noradrenaline activates a calcium-dependent chloride conductance and increases the voltage-dependent calcium current in cultured single cells of rat portal vein, Br. J. Pharmacol. 97, 139.
42. - channels in response to noradrenaline in vascular myocytes, Br. J. Pharmacol. 104, 1000.
43. 2+ store in portal vein smooth muscle cells, J. Biol. Chem. 268, 3866.
44. Rae, J., K. Cooper, P. Gates and M. Watsky, 1991, Low access resistance perforated-patch recordings using amphotericin B. J. Neurosci. Methods 37, 15.
45. 1-adrenoceptor subtypes and noradrenaline-induced contraction in rat portal vein smooth muscle, Br. J. Pharmacol. 110, 207.
46. Terada, H. and S. Murakoa, 1972, Physicochemical properties and uncoupling activity of 3′-substituted analogues of N-phenylanthranilic acid, Mol. Pharmacol. 8, 95.
47. - channels in Xenopus oocytes, Mol. Pharmacol. 37, 720.