Heterogeneous transcripts of RIME/ingi retroposons in Trypanosoma brucei are unspliced

Molecular and Biochemical Parasitology

Volumn 82, Issue 1, 1996, Pages 131-135

  Vassella, Erik ^a,b   Roditi, Isabel ^a   Braun, Richard ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Retroposon; Trans splicing; Trypanosama brucei; Variant surface glycoprotein

Indexed keywords

CELL SURFACE PROTEIN; GLYCOPROTEIN; MESSENGER RNA;

ARTICLE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RETROPOSON; RNA SPLICING; TRYPANOSOMA BRUCEI;

TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0030581702     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-6851(96)02726-0     Document Type: Article

References (14)

1. [1] Doolittle, R.F., Feng, D.-F., Johnson, M.S. and McClure, M.A. (1989) Origins and evolutionary relationships of retroviruses. The Q. Rev. Biol. 64, 1-30.
2. [2] Kimmel, B.E., Onesmo, K., Ole-Moiyoi and Young J.R. (1987) Ingi, a 5.2 kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian LINEs. Mol. Cell. Biol. 7, 1465-1475
3. [3] Murphy, N.B., Pays, A., Tebabi, P., Coquelet, H., Guyaux, M., Steinert, M. and Pays, E. (1987) Trypanosoma brucei repeated element with unusual structure and transcriptional properties. J. Mol. Biol. 195, 855-871.
4. [4] Hasan, G., Turner, M. and Cordingley, J.S. (1984) Complete nucleotide sequence of an unusual mobile element from Trypanosoma brucei. Cell 37, 333-341.
5. [5] Skowronski, J., Fanning, T.G. and Singer, M.F. (1988) Unit length Line-1 transcripts in human teratocarcinoma cells. Mol. Cell. Biol. 1988, 1385-1397.
6. [6] Agabian, N. (1990) Trans-splicing of nuclear pre-mR-NAs. Cell 61, 1157-1160.
7. [7] Frohman, M.A., Dush, M.K. and Martin, G.R. (1988) Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 85, 8998-9002.
8. [8] Hehl, A., Vassella, E., Braun, R. and Roditi, I. (1994) A conserved stem-loop structure in the 3′ untranslated region of procyclin mRNAs regulates expression in Trypanosoma brucei. Proc. Natl. Acad. Sci. USA 91, 370-374.
9. [9] Carrington, M., Miller, N., Blum, M., Roditi, I., Wiley, D. and Turner. M. (1991) Variant specific glycoprotein of Trypanosoma brucei consists of two domains each having an independently conserved pattern of cysteine residues. J. Mol. Biol. 221, 823-835.
10. [10] Marin, F., Maranon, C., Olivares, M., Alonso, C. and Lopez, C. (1995) Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: homology of the first ORF with the Ape family of DNA repair enzymes. J. Mol. Biol. 247, 49-59.
11. [11] Eickbush, T.H. (1992) Transposing without ends: the non-LTR retrotransposable elements. New Biol. 4, 430-440.
12. [12] Mizrokhi, L.J., Georgieva, S.G. and Ilyin, Y.V. (1988) Jockey, a mobile Drosophila element similar to mammalian LINEs, is transcribed from the internal promoter by RNA polymerase II. Cell 54, 685-691.
13. [13] Huang, J. and Van der Ploeg, L.H. (1991) Requirement of a polypyrimidine tract for trans-splicing in trypanosomes: discrininating the PARP promoter from the immediately adjacent 3′ splice acceptor site. EMBO J. 10, 3877-3885.
14. [14] Maga, J.A., Widmer, G. and LeBowitz, J.H. (1995) Leishmania RNA virus 1-mediated cap-independent translation. Mol. Cell Biol. 15, 4884-4889.